Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

Analysis of the Bacterial Response to Ru(CO)3Cl(Glycinate) (CORM-3) and the Inactivated Compound Identifies the Role Played by the Ruthenium Compound and Reveals Sulfur-Containing Species as a Major Target of CORM-3 Action

(2013) Samantha McLean et al.   ANTIOXIDANTS & REDOX SIGNALING

Cytochrome bd-I in Escherichia coli is less sensitive than cytochromes bd-II or bo′' to inhibition by the carbon monoxide-releasing molecule, CORM-3

(2013) Helen E. Jesse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Metal carbonyls supported on iron oxide nanoparticles to trigger the CO-gasotransmitter release by magnetic heating

(2013) Peter C. Kunz et al.   CHEMICAL COMMUNICATIONS

Enzyme-triggered CO-releasing molecules (ET-CORMs): Evaluation of biological activity in relation to their structure

(2013) S. Romanski et al.   FREE RADICAL BIOLOGY AND MEDICINE

CO and CO-releasing molecules in medicinal chemistry

(2013) Fabio Zobi   Future Medicinal Chemistry

Next Generation PhotoCORMs: Polynuclear Tricarbonylmanganese(I)-Functionalized Polypyridyl Metallodendrimers

(2013) Preshendren Govender et al.   INORGANIC CHEMISTRY

Synthesis, Spectroscopic Properties, and Photoinduced CO-Release Studies of Functionalized Ruthenium(II) Polypyridyl Complexes: Versatile Building Blocks for Development of CORM–Peptide Nucleic Acid Bioconjugates

(2013) Caroline Bischof et al.   INORGANIC CHEMISTRY

Live-Fibroblast IR Imaging of a Cytoprotective PhotoCORM Activated with Visible Light

(2013) Fabio Zobi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal-Free CO Releasing Molecule Activated by Green Light

(2013) Lovely Angel Panamparambil Antony et al.   ORGANIC LETTERS

Synthesis and Performance of Acyloxy-diene-Fe(CO)3 Complexes with Variable Chain Lengths as Enzyme-Triggered Carbon Monoxide-Releasing Molecules

(2013) Svetlana Botov et al.   ORGANOMETALLICS

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

A Selective Fluorescent Probe for Carbon Monoxide Imaging in Living Cells

(2012) Jing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lighting up Carbon Monoxide: Fluorescent Probes for Monitoring CO in Living Cells

(2012) Lin Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ru(CO)3Cl(Glycinate) (CORM-3): A Carbon Monoxide–Releasing Molecule with Broad-Spectrum Antimicrobial and Photosensitive Activities Against Respiration and Cation Transport in Escherichia coli

(2012) Jayne Louise Wilson et al.   ANTIOXIDANTS & REDOX SIGNALING

CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)3(tpm)]+

(2012) G. Dördelmann et al.   CHEMICAL COMMUNICATIONS

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Theoretical Insights into the Mechanism of Carbon Monoxide (CO) Release from CO-Releasing Molecules

(2012) Sai Vikrama Chaitanya Vummaleti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antibacterial Effects of Carbon Monoxide

(2012) Jayne Louise Wilson et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study

(2012) Steffen Romanski et al.   DALTON TRANSACTIONS

Characterization of a versatile organometallic pro-drug (CORM) for experimental CO based therapeutics

(2012) João D. Seixas et al.   DALTON TRANSACTIONS

A Comparative Study of Tricarbonylmanganese Photoactivatable CO Releasing Molecules (PhotoCORMs) by Using the Myoglobin Assay and Time-Resolved IR Spectroscopy

(2012) Wilhelm Huber et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Syntheses, Structures, and Properties of New Manganese Carbonyls as Photoactive CO-Releasing Molecules: Design Strategies That Lead to CO Photolability in the Visible Region

(2012) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme

(2012) M.F.A. Santos et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Bioorthogonal oxime ligation of a Mo(CO)4(N–N) CO-releasing molecule (CORM) to a TGF β-binding peptide

(2012) Hendrik Pfeiffer et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation

(2012) Brian W. Michel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron Dienylphosphate Tricarbonyl Complexes as Water-Soluble Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2012) Steffen Romanski et al.   ORGANOMETALLICS

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

(2012) Ana R. Marques et al.   ORGANOMETALLICS

A peptide-based material for therapeutic carbon monoxide delivery

(2012) John B. Matson et al.   Soft Matter

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

(2011) Ana C. Pena et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules

(2011) Mathieu Desmard et al.   ANTIOXIDANTS & REDOX SIGNALING

Photochemically activated carbon monoxide release for biological targets. Toward developing air-stable photoCORMs labilized by visible light

(2011) R. Dale Rimmer et al.   COORDINATION CHEMISTRY REVIEWS

Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins

(2011) T. Santos-Silva et al.   CURRENT MEDICINAL CHEMISTRY

[Mn(CO)4{S2CNMe(CH2CO2H)}], a new water-soluble CO-releasing molecule

(2011) Sian H. Crook et al.   DALTON TRANSACTIONS

Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes

(2011) Anthony J. Atkin et al.   DALTON TRANSACTIONS

Polymer Conjugates of Photoinducible CO-Releasing Molecules

(2011) Nadine E. Brückmann et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Silicium Dioxide Nanoparticles As Carriers for Photoactivatable CO-Releasing Molecules (PhotoCORMs)

(2011) Gregor Dördelmann et al.   INORGANIC CHEMISTRY

PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications

(2011) Ulrich Schatzschneider   INORGANICA CHIMICA ACTA

Investigation of light-triggered carbon monoxide release from two manganese photoCORMs by IR, UV–Vis and EPR spectroscopy

(2011) Hans-Martin Berends et al.   INORGANICA CHIMICA ACTA

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex

(2011) Teresa Santos-Silva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Potential photoactivated metallopharmaceuticals: from active molecules to supported drugs

(2010) Daniel Crespy et al.   CHEMICAL COMMUNICATIONS

CO Releasing Properties and Cytoprotective Effect ofcis-trans- [ReII(CO)2Br2L2]nComplexes

(2010) Fabio Zobi et al.   INORGANIC CHEMISTRY

Group 6 Carbon Monoxide-Releasing Metal Complexes with Biologically-Compatible Leaving Groups

(2010) Wei-Qiang Zhang et al.   INORGANIC CHEMISTRY

Dicarbonyl-bis(cysteamine)iron(II): A light induced carbon monoxide releasing molecule based on iron (CORM-S1)

(2010) Robert Kretschmer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

High throughput headspace GC-MS quantitative method to measure the amount of carbon monoxide in treated tuna fish

(2010) Gianluca Bartolucci et al.   JOURNAL OF MASS SPECTROMETRY

Carbon monoxide releasing molecule-3 inhibits concurrent tumor necrosis factor-α- and interleukin-1β-induced expression of adhesion molecules on human gingival fibroblasts

(2010) H. Song et al.   JOURNAL OF PERIODONTAL RESEARCH

Carbon Monoxide-Releasing Micelles for Immunotherapy

(2010) Urara Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]− derivatives

(2010) Tamil Selvi Pitchumony et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diversity and design of metal-based carbon monoxide-releasing molecules (CO-RMs) in aqueous systems: revealing the essential trends

(2009) Wei-Qiang Zhang et al.   DALTON TRANSACTIONS

Sonogashira and “Click” reactions for the N-terminal and side-chain functionalization of peptides with [Mn(CO)3(tpm)]+-based CO releasing molecules (tpm = tris(pyrazolyl)methane)

(2009) Hendrik Pfeiffer et al.   DALTON TRANSACTIONS

Therapeutic applications of the gaseous mediators carbon monoxide and hydrogen sulfide

(2009) Gerard L Bannenberg et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A Photochemical Precursor for Carbon Monoxide Release in Aerated Aqueous Media

(2009) R. Dale Rimmer et al.   INORGANIC CHEMISTRY

A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

(2008) Mathieu Desmard et al.   FASEB JOURNAL

Carbon Monoxide-releasing Antibacterial Molecules Target Respiration and Global Transcriptional Regulators

(2008) Kelly S. Davidge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes

(2008) M. I. Guillen et al.   RHEUMATOLOGY