Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors

Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer

(2011) M. Ferrando et al.   ANGIOGENESIS

Therapeutic Potential of Pegylated Hemin for Reactive Oxygen Species-Related Diseases via Induction of Heme Oxygenase-1: Results from a Rat Hepatic Ischemia/Reperfusion Injury Model

(2011) J. Fang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects

(2010) Hiroshi Maeda   BIOCONJUGATE CHEMISTRY

Heme Oxygenase-1/Carbon Monoxide Induces Vascular Endothelial Growth Factor Expression via p38 Kinase-dependent Activation of Sp1

(2010) Heng-Huei Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: Analogy between angina pectoris and solid tumors and enhancement of the EPR effect

(2010) Hiroshi Maeda   JOURNAL OF CONTROLLED RELEASE

Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder

(2010) Miyake   ONCOLOGY REPORTS

Polymer therapeutics: Clinical applications and challenges for development

(2009) María J. Vicent et al.   ADVANCED DRUG DELIVERY REVIEWS

Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application

(2009) Takahiro Seki et al.   CANCER SCIENCE

Preclinical and clinical studies of anticancer agent-incorporating polymer micelles

(2009) Yasuhiro Matsumura et al.   CANCER SCIENCE

Dual Pathways of Carbon Monoxide–Mediated Vasoregulation

(2009) Brian D. Lamon et al.   CIRCULATION RESEARCH

Elevating Blood Pressure as a Strategy to Increase Tumor-targeted Delivery of Macromolecular Drug SMANCS: Cases of Advanced Solid Tumors

(2009) Akinori Nagamitsu et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both

(2009) Atsunori Nakao et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Heme Oxygenase-1 and Carbon Monoxide in Vascular Pathobiology

(2008) Jozef Dulak et al.   CIRCULATION

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS