标题
Involvement of Nrf2 in Ocular Diseases
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2017, Issue -, Pages 1-18
出版商
Hindawi Limited
发表日期
2017-04-04
DOI
10.1155/2017/1703810
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Apoptosis and Oxidative Stress in Neurodegenerative Diseases
- (2018) Elena Radi et al. JOURNAL OF ALZHEIMERS DISEASE
- Inter-rater and intra-rater reliability outcomes of a rapid bacteria counting system with pressure ulcer samples
- (2017) G. Nakagami et al. Journal of Wound Care
- Feeding preference of Plutella xylostella for leaves treated with plant extracts
- (2016) IRYS F.S. COUTO et al. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
- Heme oxygenase 1 controls early innate immune response of macrophages toSalmonellaTyphimurium infection
- (2016) Anna-Maria Mitterstiller et al. CELLULAR MICROBIOLOGY
- A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment
- (2016) Xiangyang Wu et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Quercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathway
- (2016) Xin-Rong Xu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Tools to fight the cataract epidemic: A review of experimental animal models that mimic age related nuclear cataract
- (2016) Julie C. Lim et al. EXPERIMENTAL EYE RESEARCH
- Protein profiles in cortical and nuclear regions of aged human donor lenses: A confocal Raman microspectroscopic and imaging study
- (2016) Gijs F.J.M. Vrensen et al. EXPERIMENTAL EYE RESEARCH
- Assessment of structure, stability and aggregation of soluble lens proteins and alpha-crystallin upon non-enzymatic glycation: The pathomechanisms underlying cataract development in diabetic patients
- (2016) Reza Yousefi et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- The Outflow Pathway: A Tissue With Morphological and Functional Unity
- (2016) Sergio Claudio Saccà et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Simultaneous activation of Nrf2 and elevation of antioxidant compounds for reducing oxidative stress and chronic inflammation in human Alzheimer's disease
- (2016) Kedar N. Prasad MECHANISMS OF AGEING AND DEVELOPMENT
- Cell line donor genotype and its influence on experimental phenotype: Toll-like receptor SNPs and potential variability in innate immunity
- (2016) Sara A. Tokarz et al. MOLECULAR GENETICS AND METABOLISM
- The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults
- (2016) Małgorzata Nita et al. Oxidative Medicine and Cellular Longevity
- DL-3-n-butylphthalide delays the onset and progression of diabetic cataract by inhibiting oxidative stress in rat diabetic model
- (2016) Fuxu Wang et al. Scientific Reports
- The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation
- (2016) Xiaobin Liu et al. Redox Biology
- Oxidative Lipidomics Coming of Age: Advances in Analysis of Oxidized Phospholipids in Physiology and Pathology
- (2015) Corinne M. Spickett et al. ANTIOXIDANTS & REDOX SIGNALING
- Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases
- (2015) Olga Gorelenkova Miller et al. ARCHIVES OF TOXICOLOGY
- Escin activates AKT-Nrf2 signaling to protect retinal pigment epithelium cells from oxidative stress
- (2015) Kaijun Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic
- (2015) Maria A. O’Connell et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues
- (2015) Bijaya Upadhyaya et al. EXPERIMENTAL EYE RESEARCH
- Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing
- (2015) Lars Bellner et al. FASEB JOURNAL
- Oxidative stress response and Nrf2 signaling in aging
- (2015) Hongqiao Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular basis of the Keap1–Nrf2 system
- (2015) Takafumi Suzuki et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2—a therapeutic target for the treatment of neurodegenerative diseases
- (2015) Delinda A. Johnson et al. FREE RADICAL BIOLOGY AND MEDICINE
- Protective Effects of Resveratrol against UVA-Induced Damage in ARPE19 Cells
- (2015) Chi-Ming Chan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Activation of the UPR Protects against Cigarette Smoke-induced RPE Apoptosis through Up-Regulation of Nrf2
- (2015) Chuangxin Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion
- (2015) Zhenhua Xu et al. JOURNAL OF NEUROCHEMISTRY
- Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration
- (2015) M. R. Terluk et al. JOURNAL OF NEUROSCIENCE
- Unfolded protein response is activated in aged retinas
- (2015) Austin R. Lenox et al. NEUROSCIENCE LETTERS
- Photo-damage, photo-protection and age-related macular degeneration
- (2015) Melisa D. Marquioni-Ramella et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- Antioxidant responses and cellular adjustments to oxidative stress
- (2015) Cristina Espinosa-Diez et al. Redox Biology
- Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells
- (2015) SHUI-PING YANG et al. Molecular Medicine Reports
- Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells
- (2014) Periyasamy Palsamy et al. EXPERIMENTAL EYE RESEARCH
- Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts
- (2014) Periyasamy Palsamy et al. FREE RADICAL BIOLOGY AND MEDICINE
- Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling
- (2014) Hui Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Curcumin inhibits human retinal pigment epithelial cell proliferation
- (2014) YUN SUN et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Loss of Thiol Repair Systems in Human Cataractous Lenses
- (2014) M. Wei et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- Glutaredoxin 2 (Grx2) Gene Deletion Induces Early Onset of Age-dependent Cataracts in Mice
- (2014) Hongli Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The mechanism of UVB irradiation induced-apoptosis in cataract
- (2014) Yinghong Ji et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Nrf2 Amplifies Oxidative Stress via Induction of Klf9
- (2014) Shoshanna N. Zucker et al. MOLECULAR CELL
- Human age-related cataracts: Epigenetic suppression of the nuclear factor erythroid 2-related factor 2-mediated antioxidant system
- (2014) YUNXIA GAO et al. Molecular Medicine Reports
- Polymorphism of GST and FTO Genes in Risk Prediction of Cataract among a North Indian Population
- (2014) Anu Chandra et al. OPHTHALMIC GENETICS
- Oxidative Stress and Mitochondrial Dysfunction across Broad-Ranging Pathologies: Toward Mitochondria-Targeted Clinical Strategies
- (2014) Giovanni Pagano et al. Oxidative Medicine and Cellular Longevity
- The Proteomics of Drusen
- (2014) J. W. Crabb Cold Spring Harbor Perspectives in Medicine
- The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress
- (2014) Yun-Ching Chang et al. Frontiers in Aging Neuroscience
- Oxidative stress and its downstream signaling in aging eyes
- (2014) Maria Pinazo-duran et al. Clinical Interventions in Aging
- Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization
- (2014) Y. Li et al. Redox Biology
- NRF2 plays a protective role in diabetic retinopathy in mice
- (2013) Zhenhua Xu et al. DIABETOLOGIA
- Nrf2 signaling is impaired in the aging RPE given an oxidative insult
- (2013) Mira M. Sachdeva et al. EXPERIMENTAL EYE RESEARCH
- Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death
- (2013) Noriko Himori et al. JOURNAL OF NEUROCHEMISTRY
- Environmental light and endogenous antioxidants as the main determinants of non-cancer ocular diseases
- (2013) Sergio C. Saccà et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Self-assembly of protein aggregates in ageing disorders: the lens and cataract model
- (2013) J. I. Clark PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Cytotoxic Effects of Curcumin in Human Retinal Pigment Epithelial Cells
- (2013) Margrit Hollborn et al. PLoS One
- Promoter demethylation of Keap1 gene in human diabetic cataractous lenses
- (2012) Periyasamy Palsamy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Is sunlight exposure a risk factor for age-related macular degeneration? A systematic review and meta-analysis
- (2012) Guo-Yuan Sui et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- How does the macula protect itself from oxidative stress?
- (2012) James T. Handa MOLECULAR ASPECTS OF MEDICINE
- Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity
- (2012) Tracy P. Williamson et al. NEUROTOXICOLOGY
- Redox Proteomics in Selected Neurodegenerative Disorders: From Its Infancy to Future Applications
- (2011) D. Allan Butterfield et al. ANTIOXIDANTS & REDOX SIGNALING
- Posttranslational Modification of Cysteine in Redox Signaling and Oxidative Stress: Focus on S-Glutathionylation
- (2011) John J. Mieyal et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: Old perspective with a new angle
- (2011) Geeta Negi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- AGEs, RAGE, and Diabetic Retinopathy
- (2011) Hongliang Zong et al. Current Diabetes Reports
- Epigenetic Changes in Mitochondrial Superoxide Dismutase in the Retina and the Development of Diabetic Retinopathy
- (2011) Q. Zhong et al. DIABETES
- Corneal damage and lacrimal gland dysfunction in a smoking rat model
- (2011) Akihiro Higuchi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells
- (2011) HongLi Wu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia–reperfusion injury
- (2011) Yanhong Wei et al. FREE RADICAL BIOLOGY AND MEDICINE
- NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway
- (2011) Narimasa Yoshinaga et al. LABORATORY INVESTIGATION
- An association between polymorphism of the heme oxygenase-1 and -2 genes and age-related macular degeneration
- (2011) Ewelina Synowiec et al. MOLECULAR BIOLOGY REPORTS
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Duffy Antigen Receptor for Chemokines Mediates Chemokine Endocytosis through a Macropinocytosis-Like Process in Endothelial Cells
- (2011) Yani Zhao et al. PLoS One
- Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis
- (2011) Usha Chakravarthy et al. BMC Ophthalmology
- Glutaredoxin 2 prevents H2O2-induced cell apoptosis by protecting complex I activity in the mitochondria
- (2010) Hongli Wu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Protective effect of sulforaphane against oxidative stress: Recent advances
- (2010) Carlos Enrique Guerrero-Beltrán et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- Oxidation and age-related macular degeneration: insights from molecular biology
- (2010) Sam Khandhadia et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Compositional studies of human RPE lipofuscin
- (2010) L. S. Murdaugh et al. JOURNAL OF MASS SPECTROMETRY
- Compositional studies of human RPE lipofuscin: mechanisms of molecular modifications
- (2010) L. S. Murdaugh et al. JOURNAL OF MASS SPECTROMETRY
- α-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells
- (2010) Zhihui Feng et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract
- (2010) Malin von Otter et al. MECHANISMS OF AGEING AND DEVELOPMENT
- A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
- (2010) A. Lau et al. MOLECULAR AND CELLULAR BIOLOGY
- The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants
- (2010) Kyeong-Ah Jung et al. MOLECULES
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- The Importance of Mitochondria in Age-Related and Inherited Eye Disorders
- (2010) Stuart G. Jarrett et al. OPHTHALMIC RESEARCH
- Free Radicals, Antioxidants and Eye Diseases: Evidence from Epidemiological Studies on Cataract and Age-Related Macular Degeneration
- (2010) A.E. Fletcher OPHTHALMIC RESEARCH
- Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration
- (2009) Kurt M. Bertram et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Using LC3 to monitor autophagy flux in the retinal pigment epithelium
- (2009) Ai Ling Wang et al. Autophagy
- Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice
- (2009) Takumi Satoh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Absence of glutaredoxin1 increases lens susceptibility to oxidative stress induced by UVR-B
- (2009) Linda M. Meyer et al. EXPERIMENTAL EYE RESEARCH
- Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance
- (2009) Suryakant K. Niture et al. JOURNAL OF CELL SCIENCE
- NRF2 Cysteine Residues Are Critical for Oxidant/Electrophile-Sensing, Kelch-Like ECH-Associated Protein-1-Dependent Ubiquitination-Proteasomal Degradation, and Transcription Activation
- (2009) X. He et al. MOLECULAR PHARMACOLOGY
- Chylomicrons Promote Intestinal Absorption and Systemic Dissemination of Dietary Antigen (Ovalbumin) in Mice
- (2009) Yuehui Wang et al. PLoS One
- Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species
- (2009) Scott A. Reisman et al. TOXICOLOGICAL SCIENCES
- Tobacco Smoke: Involvement of Reactive Oxygen Species and Stable Free Radicals in Mechanisms of Oxidative Damage, Carcinogenesis and Synergistic Effects with Other Respirable Particles
- (2009) Athanasios Valavanidis et al. International Journal of Environmental Research and Public Health
- Further Observations on the Association Between Smoking and the Long-term Incidence and Progression of Age-related Macular Degeneration
- (2008) Ronald Klein ARCHIVES OF OPHTHALMOLOGY
- Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors
- (2008) Y.-A. Cao et al. BLOOD
- Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
- (2008) Assam El-Osta et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Epidemiology of Diabetes and Diabetes-Related Complications
- (2008) Anjali D Deshpande et al. PHYSICAL THERAPY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started