Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera
出版年份 2017 全文链接
标题
Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera
作者
关键词
-
出版物
ONCOGENE
Volume 36, Issue 23, Pages 3300-3311
出版商
Springer Nature
发表日期
2017-01-10
DOI
10.1038/onc.2016.478
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
- (2014) Raajit Rampal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concise Review: Cancer Cells Escape from Oncogene Addiction: Understanding the Mechanisms Behind Treatment Failure for More Effective Targeting
- (2014) Francesca Pellicano et al. STEM CELLS
- Treatment outcomes following leukemic transformation in Philadelphia-negative myeloproliferative neoplasms
- (2013) J. A. Kennedy et al. BLOOD
- Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
- (2013) J. Nangalia et al. NEW ENGLAND JOURNAL OF MEDICINE
- Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms
- (2013) Thorsten Klampfl et al. NEW ENGLAND JOURNAL OF MEDICINE
- How close are we to targeting the leukemia stem cell?
- (2012) Shanshan Pei et al. BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera
- (2012) A. Mullally et al. BLOOD
- The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans
- (2012) V. Pant et al. BLOOD
- JAK inhibitors for myeloproliferative neoplasms: clarifying facts from myths
- (2012) A. Tefferi BLOOD
- Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome
- (2012) S.-J. Zhang et al. BLOOD
- Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model
- (2012) H. Xu et al. BLOOD
- Decoupling of Tumor-Initiating Activity from Stable Immunophenotype in HoxA9-Meis1-Driven AML
- (2012) Kenneth D. Gibbs et al. Cell Stem Cell
- The Role of JAK Pathway Dysregulation in the Pathogenesis and Treatment of Acute Myeloid Leukemia
- (2012) H. J. Lee et al. CLINICAL CANCER RESEARCH
- A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
- (2012) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
- (2012) Claire Harrison et al. NEW ENGLAND JOURNAL OF MEDICINE
- Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia
- (2011) Nicolas Goardon et al. CANCER CELL
- p53 Lesions in Leukemic Transformation
- (2011) Ashot Harutyunyan et al. NEW ENGLAND JOURNAL OF MEDICINE
- JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms
- (2011) M Nakatake et al. ONCOGENE
- Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knock-in mice
- (2010) C. Marty et al. BLOOD
- Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells
- (2010) Ann Mullally et al. CANCER CELL
- Genetic Analysis of Transforming Events That Convert Chronic Myeloproliferative Neoplasms to Leukemias
- (2010) O. Abdel-Wahab et al. CANCER RESEARCH
- p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal
- (2010) Z. Zhao et al. GENES & DEVELOPMENT
- Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice
- (2010) Jean-Emmanuel Sarry et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells
- (2010) Y. Saito et al. Science Translational Medicine
- Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm
- (2009) P. A. Beer et al. BLOOD
- p53 Regulates Hematopoietic Stem Cell Quiescence
- (2009) Yan Liu et al. Cell Stem Cell
- A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q– syndrome
- (2009) Jillian L Barlow et al. NATURE MEDICINE
- Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells
- (2009) M Shimabe et al. ONCOGENE
- Mutant p53 Gain-of-Function in Cancer
- (2009) M. Oren et al. Cold Spring Harbor Perspectives in Biology
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
- Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice
- (2008) Jichun Chen et al. EXPERIMENTAL HEMATOLOGY
- Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
- (2008) Omobolaji O. Akala et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now