Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway

Caloric restriction: beneficial effects on brain aging and Alzheimer’s disease

(2016) Caroline Van Cauwenberghe et al.   MAMMALIAN GENOME

Melatonin Attenuates Memory Impairment Induced by Klotho Gene Deficiency Via Interactive Signaling Between MT2 Receptor, ERK, and Nrf2-Related Antioxidant Potential

(2015) Eun-Joo Shin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases

(2015) Margarita R. Ramis et al.   MECHANISMS OF AGEING AND DEVELOPMENT

NPY antagonism reduces adiposity and attenuates age-related imbalance of adipose tissue metabolism

(2014) Seongjoon Park et al.   FASEB JOURNAL

Diet-induced obesity accelerates the onset of terminal phenotypes in α-synuclein transgenic mice

(2014) Carola Rotermund et al.   JOURNAL OF NEUROCHEMISTRY

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

(2014) Takanobu Yamamoto et al.   PLoS One

The Cyclin-Dependent Kinase Inhibitor p27kip1Regulates Radial Stem Cell Quiescence and Neurogenesis in the Adult Hippocampus

(2014) Zoraida Andreu et al.   STEM CELLS

A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction

(2014) Takuya Chiba et al.   Scientific Reports

WISP1 Neuroprotection Requires FoxO3a Post-Translational Modulation with Autoregulatory Control of SIRT1

(2013) Shaohui Wang et al.   CURRENT NEUROVASCULAR RESEARCH

A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration

(2013) J. Graff et al.   JOURNAL OF NEUROSCIENCE

Nutrition and the biology of human ageing: Cognitive decline/food intake & caloric restriction

(2013) J. Le Coutre et al.   Journal of Nutrition Health & Aging

Nicotinamide Phosphoribosyltransferase Is Required for the Calorie Restriction-Mediated Improvements in Oxidative Stress, Mitochondrial Biogenesis, and Metabolic Adaptation

(2013) J. Song et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model

(2013) Cai-Xia Peng et al.   NEUROBIOLOGY OF AGING

Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging

(2013) Seok-Joo Park et al.   NEUROPSYCHOPHARMACOLOGY

Neuronale Insulinrezeptor-Substrat-2 Überexpression führt zu einem verminderten Aktivitätsverhalten, einem erhöhten Körperfettanteil sowie einer gestörten Glukosetoleranz während des Alterns

(2012) J Zemva et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Resveratrol and diabetic cardiac function: focus on recent in vitro and in vivo studies

(2012) Belma Turan et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling

(2012) Dingbo Shi et al.   JOURNAL OF PINEAL RESEARCH

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Greater filamin C, GSK3α, and GSK3β serine phosphorylation in insulin-stimulated isolated skeletal muscles of calorie restricted 24 month-old rats

(2012) Donel A. Sequea et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Age-associated decrease of SIRT1 expression in rat hippocampus

(2011) Ana Quintas et al.   EXPERIMENTAL GERONTOLOGY

Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol

(2011) Rosa Cristòfol et al.   JOURNAL OF PINEAL RESEARCH

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

(2011) C Anacker et al.   MOLECULAR PSYCHIATRY

Neuroprotection by neuropeptide Y in cell and animal models of Parkinson's disease

(2011) Mickael Decressac et al.   NEUROBIOLOGY OF AGING

Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet

(2010) Jill K. Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Preventing NAD+ Depletion Protects Neurons against Excitotoxicity

(2010) Dong Liu et al.   Annals of the New York Academy of Sciences

WNT1 inducible signaling pathway protein 1 (WISP1): A novel mediator linking development and disease

(2010) Barbara Berschneider et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways

(2010) Kyoung Ja Kwon et al.   Journal of Clinical Neurology

Agrp Neurons Mediate Sirt1's Action on the Melanocortin System and Energy Balance: Roles for Sirt1 in Neuronal Firing and Synaptic Plasticity

(2010) M. O. Dietrich et al.   JOURNAL OF NEUROSCIENCE

Multiple Pathways Regulating the Calorie Restriction Response in Yeast

(2010) Ofer Rahat et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes

(2010) Pil-Jae Kong et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Spatial Memory Consolidation is Associated with Induction of Several Lysine-Acetyltransferase (Histone Acetyltransferase) Expression Levels and H2B/H4 Acetylation-Dependent Transcriptional Events in the Rat Hippocampus

(2010) Olivier Bousiges et al.   NEUROPSYCHOPHARMACOLOGY

Regulation of yeast sirtuins by NAD+ metabolism and calorie restriction

(2009) Shu-Ping Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Converging Pathways in Lifespan Regulation

(2009) Sri Devi Narasimhan et al.   CURRENT BIOLOGY

An evaluation of the neuroprotective effects of melatonin in an in vitro experimental model of age-induced neuronal apoptosis

(2009) Marta Tajes Orduña et al.   JOURNAL OF PINEAL RESEARCH

Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats

(2009) Hung-Ming Chang et al.   JOURNAL OF PINEAL RESEARCH

Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway

(2009) M. Tajes et al.   JOURNAL OF PINEAL RESEARCH

Overexpression of FOXO1 in skeletal muscle does not alter longevity in mice

(2009) Tsuyoshi Chiba et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Neuroprotective effects of neuropeptide Y-Y2 and Y5 receptor agonists in vitro and in vivo

(2009) Maria Śmiałowska et al.   NEUROPEPTIDES

Calorie restriction minimizes activation of insulin signaling in response to glucose: Potential involvement of the growth hormone-insulin-like growth factor 1 axis

(2008) Hiroko Hayashi et al.   EXPERIMENTAL GERONTOLOGY

Melatonin prevents the injury-induced decline of Akt/forkhead transcription factors phosphorylation

(2008) Phil-Ok Koh   JOURNAL OF PINEAL RESEARCH

Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model

(2008) Javier Gutierrez-Cuesta et al.   JOURNAL OF PINEAL RESEARCH

Hungry for life: How the arcuate nucleus and neuropeptide Y may play a critical role in mediating the benefits of calorie restriction

(2008) Robin K. Minor et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Calorie restriction ameliorates neurodegenerative phenotypes in forebrain-specific presenilin-1 and presenilin-2 double knockout mice

(2007) Pu Wu et al.   NEUROBIOLOGY OF AGING

Effects of pinealectomy and exogenous melatonin on ghrelin and peptide YY in gastrointestinal system and neuropeptide Y in hypothalamic arcuate nucleus: Immunohistochemical studies in male rats

(2007) Mehmet Aydin et al.   REGULATORY PEPTIDES