Melatonin Attenuates Memory Impairment Induced by Klotho Gene Deficiency Via Interactive Signaling Between MT2 Receptor, ERK, and Nrf2-Related Antioxidant Potential

The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging

(2016) C-C Hsieh et al.   Aging-US

Physiology and pharmacology of melatonin in relation to biological rhythms

(2014) Jolanta B. Zawilska et al.   Pharmacological Reports

Melatonin Receptors Mediate Improvements of Survival in a Model of Polymicrobial Sepsis

(2013) Tobias Fink et al.   CRITICAL CARE MEDICINE

A novel melatonin agonist Neu-P11 facilitates memory performance and improves cognitive impairment in a rat model of Alzheimer' disease

(2013) Pingping He et al.   HORMONES AND BEHAVIOR

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

(2013) Esther Parada et al.   JOURNAL OF PINEAL RESEARCH

Role of adult neurogenesis in hippocampus-dependent memory, contextual fear extinction and remote contextual memory: New insights from ERK5 MAP kinase

(2013) Yung-Wei Pan et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging

(2013) Seok-Joo Park et al.   NEUROPSYCHOPHARMACOLOGY

Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ

(2012) Eun-Joo Shin et al.   BEHAVIOURAL BRAIN RESEARCH

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model

(2012) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes

(2012) Seithikurippu R. Pandi-Perumal et al.   NEUROTOXICITY RESEARCH

The hormonal Zeitgeber melatonin: role as a circadian modulator in memory processing

(2012) Oliver Rawashdeh et al.   Frontiers in Molecular Neuroscience

Protective potential of IL-6 against trimethyltin-induced neurotoxicity in vivo

(2011) Hoang-Yen Phi Tran et al.   FREE RADICAL BIOLOGY AND MEDICINE

Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light–dark cycle

(2011) Sergio Domínguez-López et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death

(2011) M. Narasimhan et al.   MOLECULAR PHARMACOLOGY

Effects of N-acetyl-cysteine treatment on glutathione depletion and a short-term spatial memory deficit in 2-cyclohexene-1-one-treated rats

(2010) Kwok Ho Christopher Choy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A potential link between phosphate and aging—Lessons from Klotho-deficient mice

(2010) Makoto Kuro-o   MECHANISMS OF AGEING AND DEVELOPMENT

Melatonin: Signaling mechanisms of a pleiotropic agent

(2009) Rüdiger Hardeland   BIOFACTORS

Fustin flavonoid attenuates β-amyloid (1-42)-induced learning impairment

(2009) Chun-Hui Jin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Klotho as a regulator of oxidative stress and senescence

(2008) Makoto Kuro-o   BIOLOGICAL CHEMISTRY

Melatonin signaling in mouse cerebellar granule cells with variable native MT1 and MT2 melatonin receptors

(2008) Marta Imbesi et al.   BRAIN RESEARCH

Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice

(2008) M. Shiozaki et al.   NEUROSCIENCE