标题
Protein O-GlcNAcylation: emerging mechanisms and functions
作者
关键词
-
出版物
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 18, Issue 7, Pages 452-465
出版商
Springer Nature
发表日期
2017-05-10
DOI
10.1038/nrm.2017.22
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- O -GlcNAc Transferase Is Essential for Sensory Neuron Survival and Maintenance
- (2017) Cathy Su et al. JOURNAL OF NEUROSCIENCE
- Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode
- (2017) Baobin Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- O-GlcNAc transferase regulates excitatory synapse maturity
- (2017) Olof Lagerlöf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic analysis reveals O-GlcNAc modification on proteins with key regulatory functions inArabidopsis
- (2017) Shou-Ling Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode
- (2017) Baobin Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells?
- (2016) Zebulon G. Levine et al. Annual Review of Biochemistry
- Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins
- (2016) R. Trapannone et al. BIOCHEMICAL JOURNAL
- RETRACTED: Modification of TAK1 by O-linked N -acetylglucosamine facilitates TAK1 activation and promotes M1 macrophage polarization
- (2016) Dongmei Zhang et al. CELLULAR SIGNALLING
- O-GlcNAcase deficiency suppresses skeletal myogenesis and insulin sensitivity in mice through the modulation of mitochondrial homeostasis
- (2016) Xun Wang et al. DIABETOLOGIA
- Role of TET enzymes in DNA methylation, development, and cancer
- (2016) Kasper Dindler Rasmussen et al. GENES & DEVELOPMENT
- Human RNA Polymerase II Promoter Recruitmentin VitroIs Regulated byO-LinkedN-Acetylglucosaminyltransferase (OGT)
- (2016) Brian A. Lewis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DrosophilaO-GlcNAcase Deletion Globally Perturbs ChromatinO-GlcNAcylation
- (2016) Ilhan Akan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity
- (2016) S. Kim et al. JOURNAL OF NEUROSCIENCE
- Genome-wide chemical mapping of O-GlcNAcylated proteins in Drosophila melanogaster
- (2016) Ta-Wei Liu et al. Nature Chemical Biology
- Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
- (2016) Mahima Swamy et al. NATURE IMMUNOLOGY
- Loss ofO-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration
- (2016) Andrew C. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesis
- (2016) Qinghua Zeng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The nutrient sensor OGT in PVN neurons regulates feeding
- (2016) O. Lagerlof et al. SCIENCE
- SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells
- (2016) Samuel A Myers et al. eLife
- Regulatory O-GlcNAcylation sites on FoxO1 are yet to be identified
- (2015) Yann Fardini et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phosphoinositides: Key modulators of energy metabolism
- (2015) Dave Bridges et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- O-GlcNAc signaling in cancer metabolism and epigenetics
- (2015) Jay Prakash Singh et al. CANCER LETTERS
- O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster
- (2015) Sujin Park et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice
- (2015) Yong Ryoul Yang et al. DIABETOLOGIA
- Global increase in O-linked N-acetylglucosamine modification promotes osteoblast differentiation
- (2015) Takahiro Koyama et al. EXPERIMENTAL CELL RESEARCH
- A little sugar goes a long way: The cell biology of O-GlcNAc
- (2015) Michelle R. Bond et al. JOURNAL OF CELL BIOLOGY
- O-GlcNAc occurs cotranslationally to stabilize nascent polypeptide chains
- (2015) Yanping Zhu et al. Nature Chemical Biology
- O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease
- (2015) Nicholas P. Marotta et al. Nature Chemistry
- The active site of O-GlcNAc transferase imposes constraints on substrate sequence
- (2015) Shalini Pathak et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Diabetes-associated dysregulation ofO-GlcNAcylation in rat cardiac mitochondria
- (2015) Partha S. Banerjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth
- (2015) Xiongjian Rao et al. Nature Communications
- The active site of O-GlcNAc transferase imposes constraints on substrate sequence
- (2015) Shalini Pathak et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure
- (2015) Emilyn U. Alejandro et al. Cell Reports
- O-GlcNAcylation regulates ischemia-induced neuronal apoptosis through AKT signaling
- (2015) Jianhua Shi et al. Scientific Reports
- Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway
- (2014) Zhao V. Wang et al. CELL
- Glucose Regulates Mitochondrial Motility via Milton Modification by O-GlcNAc Transferase
- (2014) Gulcin Pekkurnaz et al. CELL
- O-GlcNAc Transferase Enables AgRP Neurons to Suppress Browning of White Fat
- (2014) Hai-Bin Ruan et al. CELL
- O-GlcNAcylation Prevents Aggregation of the Polycomb Group Repressor Polyhomeotic
- (2014) Maria Cristina Gambetta et al. DEVELOPMENTAL CELL
- O-GlcNAcase: Promiscuous Hexosaminidase or Key Regulator ofO-GlcNAc Signaling?
- (2014) Jana Alonso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TargetingO-Glycosyltransferase (OGT) to Promote Healing of Diabetic Skin Wounds
- (2014) Kasper Runager et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-GlcNAc and the Epigenetic Regulation of Gene Expression
- (2014) Brian A. Lewis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential Regulation of the Ten-Eleven Translocation (TET) Family of Dioxygenases byO-Linked β-N-Acetylglucosamine Transferase (OGT)
- (2014) Qiao Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Making of a Sweet Modification: Structure and Function ofO-GlcNAc Transferase
- (2014) John Janetzko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High Glucose-inducedO-GlcNAcylated Carbohydrate Response Element-binding Protein (ChREBP) Mediates Mesangial Cell Lipogenesis and Fibrosis
- (2014) Min-Jung Park et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Emerging Link betweenO-GlcNAc and Alzheimer Disease
- (2014) Yanping Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of keratinocyte differentiation by O-GlcNAcylation
- (2014) Kyung-Cheol Sohn et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- O-GlcNAcylation of AMPA Receptor GluA2 Is Associated with a Novel Form of Long-Term Depression at Hippocampal Synapses
- (2014) E. W. Taylor et al. JOURNAL OF NEUROSCIENCE
- O-GlcNAc Modification of therunt-Related Transcription Factor 2 (Runx2) Links Osteogenesis and Nutrient Metabolism in Bone Marrow Mesenchymal Stem Cells
- (2014) Alexis K. Nagel et al. MOLECULAR & CELLULAR PROTEOMICS
- O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling via Regulation of the HIF-1 Pathway
- (2014) Christina M. Ferrer et al. MOLECULAR CELL
- O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation
- (2014) Bin Guo et al. NATURE CELL BIOLOGY
- O-GlcNAcylation regulates EZH2 protein stability and function
- (2014) C.-S. Chu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-GlcNAc reports ambient temperature and confers heat resistance on ectotherm development
- (2014) P. T. Radermacher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glycosylation of the Nuclear Pore
- (2014) Bin Li et al. TRAFFIC
- O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease
- (2013) Michelle R. Bond et al. Annual Review of Nutrition
- Requirement of decreased O-GlcNAc glycosylation of Mef2D for its recruitment to the myogenin promoter
- (2013) Mitsutaka Ogawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination
- (2013) Min-Dian Li et al. Cell Metabolism
- Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock
- (2013) Krista Kaasik et al. Cell Metabolism
- TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
- (2013) Rachel Deplus et al. EMBO JOURNAL
- Insulin signaling controls the expression of O-GlcNAc transferase and its interaction with lipid microdomains
- (2013) Yobana Perez-Cervera et al. FASEB JOURNAL
- Deciphering post-translational modification codes
- (2013) Adam P. Lothrop et al. FEBS LETTERS
- Defining the structural origin of the substrate sequence independence of O-GlcNAcase using a combination of molecular docking and dynamics simulation
- (2013) Joanne C Martin et al. GLYCOBIOLOGY
- Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR)
- (2013) Wahiba Berrabah et al. HEPATOLOGY
- Epigenetic Switching by the Metabolism-sensing Factors in the Generation of Orexin Neurons from Mouse Embryonic Stem Cells
- (2013) Koji Hayakawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ten-Eleven Translocation 1 (Tet1) Is Regulated byO-LinkedN-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells
- (2013) Feng-Tao Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Protein Degradation by O-GlcNAcylation: Crosstalk with Ubiquitination
- (2013) Hai-Bin Ruan et al. MOLECULAR & CELLULAR PROTEOMICS
- Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells
- (2013) Pietro Vella et al. MOLECULAR CELL
- Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
- (2013) Jeffrey R. Erickson et al. NATURE
- FOXOs: signalling integrators for homeostasis maintenance
- (2013) Astrid Eijkelenboom et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase
- (2013) M. B. Lazarus et al. SCIENCE
- Activation of the Transcriptional Function of the NF- B Protein c-Rel by O-GlcNAc Glycosylation
- (2013) P. Ramakrishnan et al. Science Signaling
- Cracking the O-GlcNAc code in metabolism
- (2013) Hai-Bin Ruan et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability
- (2012) Hai-Bin Ruan et al. Cell Metabolism
- O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network
- (2012) Hyonchol Jang et al. Cell Stem Cell
- Synergy of Peptide and Sugar in O-GlcNAcase Substrate Recognition
- (2012) Marianne Schimpl et al. CHEMISTRY & BIOLOGY
- A role for O-GlcNAcylation in setting circadian clock speed
- (2012) E. Y. Kim et al. GENES & DEVELOPMENT
- Modification of STIM1 byO-linkedN-Acetylglucosamine (O-GlcNAc) Attenuates Store-operated Calcium Entry in Neonatal Cardiomyocytes
- (2012) Xiaoyuan Zhu-Mauldin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of Dynamin-related Protein 1 (DRP1) Function by IncreasedO-linked-β-N-acetylglucosamine Modification (O-GlcNAc) in Cardiac Myocytes
- (2012) Thomas Gawlowski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Increase inO-LinkedN-Acetylglucosamine Protein Modification Stimulates Chondrogenic Differentiation Bothin Vitroandin Vivo
- (2012) Jessica Andrés-Bergós et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-GlcNAc Transferase Is Involved in Glucocorticoid Receptor-mediated Transrepression
- (2012) Min-Dian Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TET2 promotes histone O-GlcNAcylation during gene transcription
- (2012) Qiang Chen et al. NATURE
- Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation
- (2012) Jessica E Rexach et al. Nature Chemical Biology
- Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
- (2012) Scott A Yuzwa et al. Nature Chemical Biology
- linking metabolism to epigenetics through O-GlcNAcylation
- (2012) John A. Hanover et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases
- (2012) P. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF- B acetylation and transcription
- (2012) D. F. Allison et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism
- (2012) W. Yi et al. SCIENCE
- Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease
- (2011) Gerald W. Hart et al. Annual Review of Biochemistry
- O-GlcNAc modification of PPARγ reduces its transcriptional activity
- (2011) Suena Ji et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Terminal differentiation program of skeletal myogenesis is negatively regulated by O-GlcNAc glycosylation
- (2011) Mitsutaka Ogawa et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- O-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver
- (2011) C. Guinez et al. DIABETES
- Pleiotropic and Age-dependent Effects of Decreased Protein Modification byO-LinkedN-Acetylglucosamine on Pancreatic β-Cell Function and Vascularization
- (2011) Yudi Soesanto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of human O-GlcNAc transferase and its complex with a peptide substrate
- (2011) Michael B. Lazarus et al. NATURE
- Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death
- (2011) Domagoj Vucic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- O-GlcNAc-Specific Antibody CTD110.6 Cross-Reacts with N-GlcNAc2-Modified Proteins Induced under Glucose Deprivation
- (2011) Takahiro Isono PLoS One
- Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway
- (2011) S. Daou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells
- (2011) S. A. Myers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes
- (2010) Matthew S. Macauley et al. CHEMISTRY & BIOLOGY
- Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy
- (2010) S. Yokoe et al. GLYCOBIOLOGY
- BlockingO-Linked GlcNAc Cycling inDrosophilaInsulin-producing Cells Perturbs Glucose-Insulin Homeostasis
- (2010) Osamu Sekine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
- (2010) Johanna C. Scheuermann et al. NATURE
- Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
- (2010) S A Caldwell et al. ONCOGENE
- O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart
- (2010) Lewis J. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity
- (2010) D. C. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-GlcNAc protein modification in plants: Evolution and function
- (2009) Neil E. Olszewski et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Regulation of Insulin Receptor Substrate 1 (IRS-1)/AKT Kinase-mediated Insulin Signaling byO-Linked β-N-Acetylglucosamine in 3T3-L1 Adipocytes
- (2009) Stephen A. Whelan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-LinkedN-Acetylglucosamine Modification on CCAAT Enhancer-binding Protein β
- (2009) Xi Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)
- (2009) D. A. R. Sinclair et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Essential Role of the Glycosyltransferase Sxc/Ogt in Polycomb Repression
- (2009) Maria Cristina Gambetta et al. SCIENCE
- Regulation of Akt signaling by O-GlcNAc in euglycemia
- (2008) Yudi A. Soesanto et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Cardioprotection by N -Acetylglucosamine Linkage to Cellular Proteins
- (2008) Steven P. Jones et al. CIRCULATION
- Up-regulation ofO-GlcNAc Transferase with Glucose Deprivation in HepG2 Cells Is Mediated by Decreased Hexosamine Pathway Flux
- (2008) Rodrick P. Taylor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucose Deprivation StimulatesO-GlcNAc Modification of Proteins through Up-regulation ofO-LinkedN-Acetylglucosaminyltransferase
- (2008) Rodrick P. Taylor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-GlcNAc Regulates FoxO Activation in Response to Glucose
- (2008) Michael P. Housley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMP-activated Protein Kinase and p38 MAPK ActivateO-GlcNAcylation of Neuronal Proteins during Glucose Deprivation
- (2008) Win D. Cheung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased Enzymatic O-GlcNAcylation of Mitochondrial Proteins Impairs Mitochondrial Function in Cardiac Myocytes Exposed to High Glucose
- (2008) Yong Hu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of theO-Linked β-N-Acetylglucosamine Transferase by Insulin Signaling
- (2008) Stephen A. Whelan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
- (2008) Xiaoyong Yang et al. NATURE
- NF B activation is associated with its O-GlcNAcylation state under hyperglycemic conditions
- (2008) W. H. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatic Glucose Sensing via the CREB Coactivator CRTC2
- (2008) R. Dentin et al. SCIENCE
- o-GlcNAc transferase is activated by CaMKIV-dependent phosphorylation under potassium chloride-induced depolarization in NG-108-15 cells
- (2007) Minseok Song et al. CELLULAR SIGNALLING
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started