Myocardial stress and autophagy: mechanisms and potential therapies

MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy

(2017) Lei Lai et al.   LIFE SCIENCES

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts

(2016) Ying Ann Chiao et al.   Aging-US

Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance

(2016) Allen M. Andres et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Posttranslational modulation of FoxO1 contributes to cardiac remodeling in post-ischemic heart failure

(2016) Ben Arpad Kappel et al.   ATHEROSCLEROSIS

Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis

(2016) Tsunenori Saito et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Lin28a protects against diabetic cardiomyopathy via the PKA/ROCK2 pathway

(2016) Shuhong Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes

(2016) Purvi C. Trivedi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1

(2016) J. Mo et al.   BIOSCIENCE REPORTS

Mitochondrial remodeling: Rearranging, recycling, and reprogramming

(2016) Roberta A. Gottlieb et al.   CELL CALCIUM

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE

(2016) Dan L. Li et al.   CIRCULATION

Aging and Autophagy in the Heart

(2016) Akihiro Shirakabe et al.   CIRCULATION RESEARCH

UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised HeartsNovelty and Significance

(2016) Manish K. Gupta et al.   CIRCULATION RESEARCH

Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice

(2016) J. Zhang et al.   CLINICAL SCIENCE

Lysosomal signaling in control of degradation pathways

(2016) Lukas A Huber et al.   CURRENT OPINION IN CELL BIOLOGY

MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice

(2016) Mingming Zhang et al.   DIABETOLOGIA

Aging is associated with hypermethylation of autophagy genes in macrophages

(2016) Hany Khalil et al.   Epigenetics

Cellular proteostasis: degradation of misfolded proteins by lysosomes

(2016) M. P. Jackson et al.   Essays in Biochemistry

Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress

(2016) Bao Li et al.   EXPERIMENTAL PHYSIOLOGY

Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles

(2016) Rosalind F. Roberts et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway

(2016) Pujika Emani Munasinghe et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats

(2016) Chao-Hung Lai et al.   International Journal of Medical Sciences

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

(2016) Thomas G. McWilliams et al.   JOURNAL OF CELL BIOLOGY

Regulation of autophagy by Beclin 1 in the heart

(2016) Yasuhiro Maejima et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart

(2016) Aleksandr Stotland et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals

(2016) Valerie P. Tan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system

(2016) Virgilio J. J. Cadete et al.   JOURNAL OF PHYSIOLOGY-LONDON

Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction

(2016) Shashi Kumar Gupta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Epigenetics and obesity cardiomyopathy: From pathophysiology to prevention and management

(2016) Yingmei Zhang et al.   PHARMACOLOGY & THERAPEUTICS

Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

(2016) Cyndi R. Morales et al.   Science Signaling

Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice

(2016) Gen-Shui Zhang et al.   Drug Design Development and Therapy

Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36

(2016) Shiguo Li et al.   Open Biology

Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

(2016) Cyndi R. Morales et al.   Science Signaling

MicroRNA-145 repairs infarcted myocardium by accelerating cardiomyocyte autophagy

(2015) Kenshi Higashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes

(2015) Hiromitsu Kanamori et al.   Autophagy

Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux

(2015) Hong Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Mechanisms of Mitochondrial Autophagy/Mitophagy in the Heart

(2015) T. Saito et al.   CIRCULATION RESEARCH

Untangling Autophagy Measurements: All Fluxed Up

(2015) R. A. Gottlieb et al.   CIRCULATION RESEARCH

Myocardial glycogen dynamics: New perspectives on disease mechanisms

(2015) Chanchal Chandramouli et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

PINK1/Parkin-mediated mitophagy in mammalian cells

(2015) Akinori Eiyama et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy and Ubiquitination in Cardiovascular Diseases

(2015) Tania Martins-Marques et al.   DNA AND CELL BIOLOGY

Time-dependent cellular response in the liver and heart in a dietary-induced obese mouse model: the potential role of ER stress and autophagy

(2015) Hsiu-Ching Hsu et al.   EUROPEAN JOURNAL OF NUTRITION

Acute effects of statin on reduction of angiopoietin-like 2 and glyceraldehyde-derived advanced glycation end-products levels in patients with acute myocardial infarction: a message from SAMIT (Statin for Acute Myocardial Infarction Trial)

(2015) Mitsuhiro Shimomura et al.   HEART AND VESSELS

The AMPK Agonist PT1 and mTOR Inhibitor 3HOI-BA-01 Protect Cardiomyocytes After Ischemia Through Induction of Autophagy

(2015) Ling Huang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Development of autophagy inducers in clinical medicine

(2015) Beth Levine et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapamycin protects cardiomyocytes against anoxia/reoxygenation injury by inducing autophagy through the PI3k/Akt pathway

(2015) Lu-qiao Wang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

This old heart: Cardiac aging and autophagy

(2015) Phyllis-Jean Linton et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of the Transcription Factor EB-PGC1α Axis by Beclin-1 Controls Mitochondrial Quality and Cardiomyocyte Death under Stress

(2015) Xiucui Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Measuring In Vivo Mitophagy

(2015) Nuo Sun et al.   MOLECULAR CELL

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

(2015) Jin-Mi Heo et al.   MOLECULAR CELL

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Decreased autophagy: a major factor for cardiomyocyte death induced by β1-adrenoceptor autoantibodies

(2015) L Wang et al.   Cell Death & Disease

Changing Shapes of Glycogen–Autophagy Nexus in Neurons: Perspective from a Rare Epilepsy

(2015) Pankaj Kumar Singh et al.   Frontiers in Neurology

Protective effects of desacyl ghrelin on diabetic cardiomyopathy

(2014) Xiao M. Pei et al.   ACTA DIABETOLOGICA

The Cardioprotection of the Insulin-Mediated PI3K/Akt/mTOR Signaling Pathway

(2014) Hong Yao et al.   American Journal of Cardiovascular Drugs

Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose

(2014) Kimberley M. Mellor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Myocardial Contractile Dysfunction Is Associated With Impaired Mitochondrial Function and Dynamics in Type 2 Diabetic but Not in Obese Patients

(2014) David Montaigne et al.   CIRCULATION

Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy

(2014) Min Xie et al.   CIRCULATION

Insulin Regulation of Myocardial Autophagy

(2014) Christian Riehle et al.   CIRCULATION JOURNAL

Adiponectin receptor 1 overexpression reduces lipid accumulation and hypertrophy in the heart of diet-induced obese mice – possible involvement of oxidative stress and autophagy

(2014) I-Pin Chou et al.   ENDOCRINE RESEARCH

(–)-Epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto–Kakizaki rats

(2014) J. Liu et al.   FREE RADICAL RESEARCH

Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease

(2014) J. Duran et al.   HUMAN MOLECULAR GENETICS

Macrophage migration inhibitory factor (MIF) knockout preserves cardiac homeostasis through alleviating Akt-mediated myocardial autophagy suppression in high-fat diet-induced obesity

(2014) X Xu et al.   INTERNATIONAL JOURNAL OF OBESITY

Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction

(2014) Qiaoling Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

(2014) Bo Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity

(2014) Bharat Jaishy et al.   JOURNAL OF LIPID RESEARCH

Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles

(2014) Zoltán Giricz et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

(2014) Takanobu Yamamoto et al.   PLoS One

Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation

(2014) Samuel E. Senyo et al.   Stem Cell Research

Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

(2014) Ahmed Gamal-Eldin Ibrahim et al.   Stem Cell Reports

Mitophagy Is Required for Acute Cardioprotection by Simvastatin

(2013) Allen M. Andres et al.   ANTIOXIDANTS & REDOX SIGNALING

Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy

(2013) Asli F. Ceylan-Isik et al.   BASIC RESEARCH IN CARDIOLOGY

Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading

(2013) Jota Oyabu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: Role of autophagy

(2013) Rui Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Essential role for UVRAG in autophagy and maintenance of cardiac function

(2013) Zongpei Song et al.   CARDIOVASCULAR RESEARCH

Fluorescence Tomography of Rapamycin-Induced Autophagy and Cardioprotection In Vivo

(2013) Howard H. Chen et al.   Circulation-Cardiovascular Imaging

Diminished Autophagy Limits Cardiac Injury in Mouse Models of Type 1 Diabetes

(2013) Xianmin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Autophagy in Ischemic Postconditioning Contributes to Cardioprotective Effects Against Ischemia/Reperfusion Injury in Rat Hearts

(2013) Chao Wei et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

(2013) Christian Riehle et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhanced autophagy ameliorates cardiac proteinopathy

(2013) Md. Shenuarin Bhuiyan et al.   JOURNAL OF CLINICAL INVESTIGATION

RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy

(2013) Oktay F. Rifki et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocardial glycophagy — A specific glycogen handling response to metabolic stress is accentuated in the female heart

(2013) M.E. Reichelt et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

miR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy

(2013) Xuesong Yin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy

(2013) Yanli Zhao et al.   PLoS One

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

(2013) Aditi U. Gurkar et al.   Nature Communications

Role of Autophagy in Glycogen Breakdown and Its Relevance to Chloroquine Myopathy

(2013) Jonathan Zirin et al.   PLOS BIOLOGY

Glycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion

(2012) Peiyong Zhai et al.   Autophagy

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

Early statin treatment prior to primary PCI for acute myocardial infarction: REPERATOR, a randomized placebo-controlled pilot trial

(2012) Simone Post et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

(2012) Xiucui Ma et al.   CIRCULATION

Rheb is a Critical Regulator of Autophagy During Myocardial Ischemia

(2012) Sebastiano Sciarretta et al.   CIRCULATION

Dissociation of Bcl-2-Beclin1 Complex by Activated AMPK Enhances Cardiac Autophagy and Protects Against Cardiomyocyte Apoptosis in Diabetes

(2012) C. He et al.   DIABETES

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

(2012) J. Korac et al.   JOURNAL OF CELL SCIENCE

Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes

(2012) Sarah Brice Russo et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart

(2012) Susan A. Marsh et al.   LIFE SCIENCES

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Ischemia-Reperfusion Injury Leads to Distinct Temporal Cardiac Remodeling in Normal versus Diabetic Mice

(2012) Megumi Eguchi et al.   PLoS One

Carbon Monoxide Improves Cardiac Function and Mitochondrial Population Quality in a Mouse Model of Metabolic Syndrome

(2012) Steve Lancel et al.   PLoS One

Verapamil stereoisomers induce antiproliferative effects in vascular smooth muscle cells via autophagy

(2012) Joshua K. Salabei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation

(2012) Xihui Xu et al.   Journal of Molecular Cell Biology

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

(2012) Ahmet Ucar et al.   Nature Communications

Autophagy anomalies in the diabetic myocardium

(2011) Kimberley M. Mellor et al.   Autophagy

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Chronic akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy

(2011) Yinan Hua et al.   BASIC RESEARCH IN CARDIOLOGY

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1

(2011) Sixin Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

(2011) Rodrigo Troncoso et al.   CARDIOVASCULAR RESEARCH

Microautophagy: lesser-known self-eating

(2011) Wen-wen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

(2011) Z. Xie et al.   DIABETES

Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy

(2011) Andrew J. Boyle et al.   EXPERIMENTAL GERONTOLOGY

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

(2011) Saskia Schlossarek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice

(2011) Kimberley M. Mellor et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

(2011) Chengqun Huang et al.   PLoS One

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

(2011) D. J. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative Stress Stimulates Autophagic Flux During Ischemia/Reperfusion

(2010) Nirmala Hariharan et al.   ANTIOXIDANTS & REDOX SIGNALING

Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells

(2010) Raquel S. Carreira et al.   Autophagy

Inhibition of autophagy in the heart induces age-related cardiomyopathy

(2010) Manabu Taneike et al.   Autophagy

Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation

(2010) Pablo Aránguiz-Urroz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism

(2010) Sixin Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy basics

(2010) Isei Tanida   MICROBIOLOGY AND IMMUNOLOGY

The administration of nonmetabolizable glucose analogues fails to suppress the development of glycogen autophagy in newborn rat hepatocytes

(2010) Stefanos A. Kalamidas et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

The origin of the autophagosomal membrane

(2010) Sharon A. Tooze et al.   NATURE CELL BIOLOGY

Autophagy Induced by Ischemic Preconditioning is Essential for Cardioprotection

(2010) Chengqun Huang et al.   Journal of Cardiovascular Translational Research

Cardiomyocyte autophagy is regulated by angiotensin II type 1 and type 2 receptors

(2009) Enzo R. Porrello et al.   Autophagy

Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA

(2009) Smadar Yitzhaki et al.   BASIC RESEARCH IN CARDIOLOGY

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

(2009) Narasimman Gurusamy et al.   CARDIOVASCULAR RESEARCH

Suppression of Phosphoinositide 3-Kinase Prevents Cardiac Aging in Mice

(2009) Yasutaka Inuzuka et al.   CIRCULATION

Autophagy in Ischemic Heart Disease

(2009) Åsa B. Gustafsson et al.   CIRCULATION RESEARCH

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

(2009) Einat Zalckvar et al.   EMBO REPORTS

Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor–Mediated Cardiomyocyte Autophagy

(2009) Enzo R. Porrello et al.   HYPERTENSION

Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis

(2009) Asli F. Ceylan-Isik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection

(2008) Hua Yuan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy in Load-Induced Heart Disease

(2008) Beverly A. Rothermel et al.   CIRCULATION RESEARCH

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Autophagy is an adaptive response in desmin-related cardiomyopathy

(2008) P. Tannous et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA