Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling

(2015) Anindita Das et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of Hypertrophy Is a Good Therapeutic Strategy in Ventricular Pressure Overload

(2015) G. G. Schiattarella et al.   CIRCULATION

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Readers, Writers, and Erasers

(2015) Thomas G. Gillette et al.   CIRCULATION RESEARCH

KATs in cancer: functions and therapies

(2015) A Farria et al.   ONCOGENE

Cycloheximide inhibits starvation-induced autophagy through mTORC1 activation

(2014) Takako Watanabe-Asano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy

(2014) Min Xie et al.   CIRCULATION

A Human Pluripotent Stem Cell Surface N-Glycoproteome Resource Reveals Markers, Extracellular Epitopes, and Drug Targets

(2014) Kenneth R. Boheler et al.   Stem Cell Reports

Switched on with magnets

(2013) Sanjay Kumar   Nature Nanotechnology

HDAC-dependent ventricular remodeling

(2013) Min Xie et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Metabolic stress–induced activation of FoxO1 triggers diabetic cardiomyopathy in mice

(2012) Pavan K. Battiprolu et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin Inhibits Cardiac Mesoderm, Not Mesendoderm, Formation During Cardiac Differentiation of Human Pluripotent Stem Cells and Modulation of Canonical Wnt Signaling Can Rescue This Inhibition

(2012) Xiaojun Lian et al.   STEM CELLS

Therapeutic Potential for HDAC Inhibitors in the Heart

(2011) Timothy A. McKinsey   Annual Review of Pharmacology and Toxicology

Reversibility of Adverse, Calcineurin-Dependent Cardiac Remodeling

(2011) Jeff M. Berry et al.   CIRCULATION RESEARCH

Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells

(2011) Steffen Wedel et al.   CLINICAL & EXPERIMENTAL METASTASIS

Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin

(2011) A. J. Malhowski et al.   HUMAN MOLECULAR GENETICS

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

(2011) D. J. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulating the Regulators: The Post-Translational Code of Class I HDAC1 and HDAC2

(2010) Chiara V. Segré et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

(2010) Denghong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment

(2010) Claudia Colussi et al.   PHARMACOLOGICAL RESEARCH

The Methylation of the TSC2 Promoter Underlies the Abnormal Growth of TSC2 Angiomyolipoma-Derived Smooth Muscle Cells

(2009) Elena Lesma et al.   AMERICAN JOURNAL OF PATHOLOGY

REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch

(2009) Mitsunori Miyazaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Vorinostat in solid and hematologic malignancies

(2009) David Siegel et al.   Journal of Hematology & Oncology

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

(2008) Pasquale Gallo et al.   CARDIOVASCULAR RESEARCH