Mitochondrial DNA in the regulation of innate immune responses

Basophils exhibit antibacterial activity through extracellular trap formation

(2015) S. Yousefi et al.   ALLERGY

Innate Immune Recognition of mtDNA—An Undercover Signal?

(2015) Thirumala-Devi Kanneganti et al.   Cell Metabolism

Cationic nanocarriers induce cell necrosis through impairment of Na+/K+-ATPase and cause subsequent inflammatory response

(2015) Xiawei Wei et al.   CELL RESEARCH

Viral RNA detection by RIG-I-like receptors

(2015) Mitsutoshi Yoneyama et al.   CURRENT OPINION IN IMMUNOLOGY

Mitochondrial DNA stress primes the antiviral innate immune response

(2015) A. Phillip West et al.   NATURE

Mitochondria: diversity in the regulation of the NLRP3 inflammasome

(2015) Prajwal Gurung et al.   TRENDS IN MOLECULAR MEDICINE

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

(2014) L. H. Boudreau et al.   BLOOD

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

(2014) Michael J. White et al.   CELL

Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

(2014) Anthony Rongvaux et al.   CELL

NADPH Oxidase-Independent Formation of Extracellular DNA Traps by Basophils

(2014) M. Morshed et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial DNA damage and atherosclerosis

(2014) Emma P.K. Yu et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

(2014) Tiffany Horng   TRENDS IN IMMUNOLOGY

Unravelling mitochondrial pathways to Parkinson's disease

(2013) I Celardo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of NOD-like Receptor-Associated Inflammasome Activation

(2013) Haitao Wen et al.   IMMUNITY

Gene Deletion of Gabarap Enhances Nlrp3 Inflammasome-Dependent Inflammatory Responses

(2013) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Transcription Factor A, an Endogenous Danger Signal, Promotes TNFα Release via RAGE- and TLR9-Responsive Plasmacytoid Dendritic Cells

(2013) Mark W. Julian et al.   PLoS One

Translation of hemodynamic stress to sterile inflammation in the heart

(2013) Hiroyuki Nakayama et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis

(2013) Zufeng Ding et al.   Scientific Reports

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure

(2012) Pedro E. Marques et al.   HEPATOLOGY

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Mitochondrial DNA and inflammatory diseases

(2011) Germaine Escames et al.   HUMAN GENETICS

Increased plasma levels of extracellular mitochondrial DNA during HIV infection: A new role for mitochondrial damage-associated molecular patterns during inflammation

(2011) Andrea Cossarizza et al.   MITOCHONDRION

Somatic Mitochondrial DNA Mutations in Mammalian Aging

(2010) Nils-Göran Larsson   Annual Review of Biochemistry

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps

(2009) Maren von Köckritz-Blickwede et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE