标题
Rational design of proteins that exchange on functional timescales
作者
关键词
-
出版物
Nature Chemical Biology
Volume 13, Issue 12, Pages 1280-1285
出版商
Springer Nature
发表日期
2017-10-24
DOI
10.1038/nchembio.2503
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Principles for designing proteins with cavities formed by curved β sheets
- (2017) Enrique Marcos et al. SCIENCE
- Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell
- (2016) Guanghong Wei et al. CHEMICAL REVIEWS
- The role of protein dynamics in the evolution of new enzyme function
- (2016) Eleanor Campbell et al. Nature Chemical Biology
- The energy landscape of adenylate kinase during catalysis
- (2015) S Jordan Kerns et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Optimization of rotamers prior to template minimization improves stability predictions made by computational protein design
- (2015) James A. Davey et al. PROTEIN SCIENCE
- Prediction of Stable Globular Proteins Using Negative Design with Non-native Backbone Ensembles
- (2015) James A. Davey et al. STRUCTURE
- The energy landscape of adenylate kinase during catalysis
- (2015) S Jordan Kerns et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Protein design algorithms predict viable resistance to an experimental antifolate
- (2015) Stephanie M. Reeve et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improving the accuracy of protein stability predictions with multistate design using a variety of backbone ensembles
- (2013) James A. Davey et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Principles for designing ideal protein structures
- (2012) Nobuyasu Koga et al. NATURE
- Iterative approach to computational enzyme design
- (2012) H. K. Privett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Computational Design of a PDZ Domain Peptide Inhibitor that Rescues CFTR Activity
- (2012) Kyle E. Roberts et al. PLoS Computational Biology
- Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
- (2011) Guillaume Bouvignies et al. NATURE
- Ultrahigh resolution protein structures using NMR chemical shift tensors
- (2011) B. J. Wylie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis
- (2011) G. Bhabha et al. SCIENCE
- An introduction to NMR-based approaches for measuring protein dynamics
- (2010) Ian R. Kleckner et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- RosettaBackrub--a web server for flexible backbone protein structure modeling and design
- (2010) F. Lauck et al. NUCLEIC ACIDS RESEARCH
- Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles
- (2010) B. D. Allen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries
- (2010) R. A. Chica et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- WW: An isolated three-stranded antiparallel β-sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state
- (2010) Edward K. Koepf et al. PROTEIN SCIENCE
- Structural origins of pH-dependent chemical shifts in the B1 domain of protein G
- (2010) Jennifer H. Tomlinson et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Role of conformational sampling in computing mutation-induced changes in protein structure and stability
- (2010) Elizabeth H. Kellogg et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Two-point anchoring of a lanthanide-binding peptide to a target protein enhances the paramagnetic anisotropic effect
- (2009) Tomohide Saio et al. JOURNAL OF BIOMOLECULAR NMR
- TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts
- (2009) Yang Shen et al. JOURNAL OF BIOMOLECULAR NMR
- Dynamic activation of an allosteric regulatory protein
- (2009) Shiou-Ru Tzeng et al. NATURE
- Interconversion between two unrelated protein folds in the lymphotactin native state
- (2008) Robbyn L. Tuinstra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NMR-detected conformational exchange observed in a computationally designed variant of protein G 1
- (2008) K. A. Crowhurst et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Protonate3D: Assignment of ionization states and hydrogen coordinates to macromolecular structures
- (2008) Paul Labute PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
- Characterization of Specific Protein Association by15N CPMG Relaxation Dispersion NMR: The GB1A34FMonomer−Dimer Equilibrium†
- (2007) JunGoo Jee et al. JOURNAL OF PHYSICAL CHEMISTRY B
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