Experimental library screening demonstrates the successful application of computational protein design to large structural ensembles

Design of protein-interaction specificity gives selective bZIP-binding peptides

(2009) Gevorg Grigoryan et al.   NATURE

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

X-ray vs. NMR structures as templates for computational protein design

(2009) Michael Schneider et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Protein Design by Directed Evolution

(2008) Christian Jäckel et al.   Annual Review of Biophysics

Advances in laboratory evolution of enzymes

(2008) Shimon Bershtein et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Design of Protein–Ligand Binding Based on the Molecular-Mechanics Energy Model

(2008) F. Edward Boas et al.   JOURNAL OF MOLECULAR BIOLOGY

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE

Thoroughly sampling sequence space: Large-scale protein design of structural ensembles

(2002) Stefan M. Larson et al.   PROTEIN SCIENCE