A non-coding function of TYRP1 mRNA promotes melanoma growth

Definition and identification of small RNA sponges: Focus on miRNA sequestration

(2017) Mélodie Migault et al.   METHODS

MAPK Pathway Inhibitors Sensitize BRAF-Mutant Melanoma to an Antibody-Drug Conjugate Targeting GPNMB

(2016) A. A. N. Rose et al.   CLINICAL CANCER RESEARCH

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

(2016) Richard S Finkel et al.   LANCET

Melanoma addiction to the long non-coding RNA SAMMSON

(2016) Eleonora Leucci et al.   NATURE

General rules for functional microRNA targeting

(2016) Doyeon Kim et al.   NATURE GENETICS

A microRNA switch regulates the rise in hypothalamic GnRH production before puberty

(2016) Andrea Messina et al.   NATURE NEUROSCIENCE

Endogenous microRNA sponges: evidence and controversy

(2016) Daniel W. Thomson et al.   NATURE REVIEWS GENETICS

Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4

(2016) Petra Hartmann et al.   Nature Communications

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

SNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma

(2015) P El Hajj et al.   BRITISH JOURNAL OF CANCER

The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo

(2015) Florian A. Karreth et al.   CELL

Hepatitis C Virus RNA Functionally Sequesters miR-122

(2015) Joseph M. Luna et al.   CELL

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma

(2015) Wei Kang et al.   Molecular Cancer

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

(2015) Miguel Vizoso et al.   NATURE MEDICINE

Inhibiting plant microRNA activity: molecularSPONGEs, targetMIMICsand STTMs all display variable efficacies against target microRNAs

(2015) Marlene Reichel et al.   PLANT BIOTECHNOLOGY JOURNAL

The Whereabouts of microRNA Actions: Cytoplasm and Beyond

(2015) Anthony K.L. Leung   TRENDS IN CELL BIOLOGY

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

(2015) Annelien Verfaillie et al.   Nature Communications

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway

(2014) Direna Alonso-Curbelo et al.   CANCER CELL

Role of miR-15/16 in CLL

(2014) Y Pekarsky et al.   CELL DEATH AND DIFFERENTIATION

Prominent role of cyclic adenosine monophosphate signalling pathway in the sensitivity of WTBRAF/WTNRAS melanoma cells to vemurafenib

(2014) Mohammad Krayem et al.   EUROPEAN JOURNAL OF CANCER

Unambiguous Identification of miRNA:Target Site Interactions by Different Types of Ligation Reactions

(2014) Stefanie Grosswendt et al.   MOLECULAR CELL

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

Identification and consequences of miRNA–target interactions — beyond repression of gene expression

(2014) Jean Hausser et al.   NATURE REVIEWS GENETICS

MicroRNA-9 controls dendritic development by targeting REST

(2014) Sebastian A Giusti et al.   eLife

Tyrosinase-related protein 1 mRNA expression in lymph node metastases predicts overall survival in high-risk melanoma patients

(2013) P El Hajj et al.   BRITISH JOURNAL OF CANCER

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

High expression of glycolytic and pigment proteins is associated with worse clinical outcome in stage III melanoma

(2013) Johan Falkenius et al.   MELANOMA RESEARCH

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets

(2013) Mohsen Khorshid et al.   NATURE METHODS

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting

(2012) Gabriel B. Loeb et al.   MOLECULAR CELL

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Functional Screen Identifies Specific MicroRNAs Capable of Inhibiting Human Melanoma Cell Viability

(2012) Jos B. Poell et al.   PLoS One

TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome

(2011) F Journe et al.   BRITISH JOURNAL OF CANCER

Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

(2011) Yvonne Tay et al.   CELL

In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma

(2011) Florian A. Karreth et al.   CELL

In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model

(2011) Stephanie David et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Competitive Regulation of Nucleolin Expression by HuR and miR-494

(2011) K. Tominaga et al.   MOLECULAR AND CELLULAR BIOLOGY

Tyrosinase related protein 1 (TYRP1/gp75) in human cutaneous melanoma

(2011) Ghanem Ghanem et al.   Molecular Oncology

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

(2011) David M Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNAi-Based Screening Identifies Kinases Interfering with Dioxin-Mediated Up-Regulation of CYP1A1 Activity

(2011) David Gilot et al.   PLoS One

An Illegitimate microRNA Target Site within the 3' UTR of MDM4 Affects Ovarian Cancer Progression and Chemosensitivity

(2010) J. Wynendaele et al.   CANCER RESEARCH

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

(2010) Frederick J Raal et al.   LANCET

Target mRNA abundance dilutes microRNA and siRNA activity

(2010) Aaron Arvey et al.   Molecular Systems Biology

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

MicroRNA sponges: Progress and possibilities

(2010) M. S. Ebert et al.   RNA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes

(2008) Q. Liu et al.   NUCLEIC ACIDS RESEARCH