Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

(2014) F. J. Carmona et al.   CANCER RESEARCH

Melanoma as a model for precision medicine in oncology

(2014) Howard L Kaufman   LANCET ONCOLOGY

Tissue prognostic biomarkers in primary cutaneous melanoma

(2014) Mario Mandalà et al.   VIRCHOWS ARCHIV

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

(2014) Paula Lopez-Serra et al.   Nature Communications

The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming

(2014) Stéphanie Cunha et al.   Cell Reports

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Phase II Trial of MEK Inhibitor Selumetinib (AZD6244, ARRY-142886) in Patients with BRAFV600E/K-Mutated Melanoma

(2013) F. Catalanotti et al.   CLINICAL CANCER RESEARCH

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis

(2013) Diego M. Marzese et al.   HUMAN MOLECULAR GENETICS

Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer

(2013) Catia Moutinho et al.   JNCI-Journal of the National Cancer Institute

Cutaneous melanoma

(2013) Alexander MM Eggermont et al.   LANCET

The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma

(2013) Howard L. Kaufman et al.   Nature Reviews Clinical Oncology

Regional Activation of the Cancer Genome by Long-Range Epigenetic Remodeling

(2012) Saul A. Bert et al.   CANCER CELL

Melanoma: from mutations to medicine

(2012) H. Tsao et al.   GENES & DEVELOPMENT

Rab5c promotes AMAP1–PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion

(2012) Yasuhito Onodera et al.   JOURNAL OF CELL BIOLOGY

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

(2012) Anirudh Prahallad et al.   NATURE

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

In melanoma ulceration, size matters

(2012) M. Teresa Villanueva   Nature Reviews Clinical Oncology

DNA methylation profiling in the clinic: applications and challenges

(2012) Holger Heyn et al.   NATURE REVIEWS GENETICS

Erratum: Illuminating the functional and structural repertoire of human TBC/RABGAPs

(2012) Marieke A. M. Frasa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling

(2012) B. S. Goueli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct DNA methylomes of newborns and centenarians

(2012) H. Heyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF -Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib

(2012) Ryan B. Corcoran et al.   Cancer Discovery

Inhibiting EGF Receptor or SRC Family Kinase Signaling Overcomes BRAF Inhibitor Resistance in Melanoma

(2012) Maria R. Girotti et al.   Cancer Discovery

Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration

(2012) Douglas G. Altman et al.   PLOS MEDICINE

Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes

(2011) Rajendra Kedlaya et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

(2011) G. C. Hon et al.   GENOME RESEARCH

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

Targeting protein-trafficking pathways alters melanoma treatment sensitivity

(2011) Z.-m. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic modeling of the effects of myoferlin on tumor cell invasion

(2011) M. C. Eisenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis

(2011) F. Fang et al.   Science Translational Medicine

An Integrated Approach to Uncover Drivers of Cancer

(2010) Uri David Akavia et al.   CELL

Epidemiology of invasive cutaneous melanoma

(2009) R. M. MacKie et al.   ANNALS OF ONCOLOGY

Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition

(2009) O. K. Mirzoeva et al.   CANCER RESEARCH

Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells

(2009) Y.-K. Yoon et al.   MOLECULAR CANCER THERAPEUTICS

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA