Structure and allosteric inhibition of excitatory amino acid transporter 1

Late-onset episodic ataxia associated with SLC1A3 mutation

(2016) Kwang-Dong Choi et al.   JOURNAL OF HUMAN GENETICS

Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk

(2016) Albert Guskov et al.   Nature Communications

Transport Rates of a Glutamate Transporter Homologue Are Influenced by the Lipid Bilayer

(2015) Benjamin C. McIlwain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development

(2015) Qian Wang et al.   JOURNAL OF PATHOLOGY

Transport domain unlocking sets the uptake rate of an aspartate transporter

(2015) Nurunisa Akyuz et al.   NATURE

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer

(2015) M van Geldermalsen et al.   ONCOGENE

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

(2015) Darragh P. O’Brien et al.   Scientific Reports

ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer

(2014) K Shimizu et al.   BRITISH JOURNAL OF CANCER

Targeting glutamine transport to suppress melanoma cell growth

(2014) Qian Wang et al.   INTERNATIONAL JOURNAL OF CANCER

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Glutamate-Based Antidepressants: Preclinical Psychopharmacology

(2013) Andrzej Pilc et al.   BIOLOGICAL PSYCHIATRY

Glutamate transporters in the biology of malignant gliomas

(2013) Stephanie M. Robert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Allosteric Modulation of an Excitatory Amino Acid Transporter: The Subtype-Selective Inhibitor UCPH-101 Exerts Sustained Inhibition of EAAT1 through an Intramonomeric Site in the Trimerization Domain

(2013) B. Abrahamsen et al.   JOURNAL OF NEUROSCIENCE

Binding thermodynamics of a glutamate transporter homolog

(2013) Nicolas Reyes et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A point mutation associated with episodic ataxia 6 increases glutamate transporter anion currents

(2012) Natalie Winter et al.   BRAIN

Opposite Movement of the External Gate of a Glutamate Transporter Homolog upon Binding Cotransported Sodium Compared with Substrate

(2011) P. J. Focke et al.   JOURNAL OF NEUROSCIENCE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hydrogen exchange mass spectrometry for studying protein structure and dynamics

(2010) Lars Konermann et al.   CHEMICAL SOCIETY REVIEWS

Regulation of Glial Glutamate Transporters by C-terminal Domains

(2010) Ariane Leinenweber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Cation Binding to the Glutamate Transporter EAAC1 Probed with Mutation of the Conserved Amino Acid Residue Thr101

(2010) Zhen Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria

(2010) Charles G. Bailey et al.   JOURNAL OF CLINICAL INVESTIGATION

The position of an arginine residue influences substrate affinity and K+ coupling in the human glutamate transporter, EAAT1

(2010) Renae M. Ryan et al.   JOURNAL OF NEUROCHEMISTRY

The Role of Excitatory Amino Acid Transporters in Cerebral Ischemia

(2010) Xiao-dong Chao et al.   NEUROCHEMICAL RESEARCH

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model

(2010) H. P. Larsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Discovery of the First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1

(2009) Anders A. Jensen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transport mechanism of a bacterial homologue of glutamate transporters

(2009) Nicolas Reyes et al.   NATURE

Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats

(2009) T. J. Crisman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate transporter blockers for elucidation of the function of excitatory neurotransmission systems

(2008) Keiko Shimamoto   CHEMICAL RECORD

Substrates and Non-transportable Analogues Induce Structural Rearrangements at the Extracellular Entrance of the Glial Glutamate Transporter GLT-1/EAAT2

(2008) Shaogang Qu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY