标题
Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases
作者
关键词
-
出版物
MOLECULES
Volume 22, Issue 12, Pages 2045
出版商
MDPI AG
发表日期
2017-11-24
DOI
10.3390/molecules22122045
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors
- (2017) Jin-Yi Zhu et al. JOURNAL OF MEDICINAL CHEMISTRY
- ATM, ATR, CHK1, CHK2 and WEE1 inhibitors in cancer and cancer stem cells
- (2017) Cyril Ronco et al. MedChemComm
- Identification of peptidic substrates for the human kinase Myt1 using peptide microarrays
- (2015) Alexander Rohe et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells
- (2015) Chad M. Toledo et al. Cell Reports
- Application of Docking and QM/MM-GBSA Rescoring to Screen for Novel Myt1 Kinase Inhibitors
- (2014) Kanin Wichapong et al. Journal of Chemical Information and Modeling
- Targeting the wee1 kinase for treatment of pediatric Down syndrome acute myeloid leukemia
- (2014) J. Timothy Caldwell et al. PEDIATRIC BLOOD & CANCER
- Pyrimidine-Based Tricyclic Molecules as Potent and Orally Efficacious Inhibitors of Wee1 Kinase
- (2014) Yunsong Tong et al. ACS Medicinal Chemistry Letters
- A Fluorescence Anisotropy–Based Myt1 Kinase Binding Assay
- (2013) Alexander Rohe et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Tumour selective targeting of cell cycle kinases for cancer treatment
- (2013) Marieke Aarts et al. CURRENT OPINION IN PHARMACOLOGY
- RNAi screening of the kinome with cytarabine in leukemias
- (2012) R. Tibes et al. BLOOD
- MEK1 inactivates Myt1 to regulate Golgi membrane fragmentation and mitotic entry in mammalian cells
- (2012) Julien Villeneuve et al. EMBO JOURNAL
- Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay
- (2012) Alexander Rohe et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery
- (2012) J P H Chow et al. ONCOGENE
- WEE1 Kinase Targeting Combined with DNA-Damaging Cancer Therapy Catalyzes Mitotic Catastrophe
- (2011) P. C. De Witt Hamer et al. CLINICAL CANCER RESEARCH
- Coupling of T161 and T14 phosphorylations protects cyclin B–CDK1 from premature activation
- (2011) Katia Coulonval et al. MOLECULAR BIOLOGY OF THE CELL
- Comprehensive analysis of kinase inhibitor selectivity
- (2011) Mindy I Davis et al. NATURE BIOTECHNOLOGY
- Checkpoint control and cancer
- (2011) R H Medema et al. ONCOGENE
- Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis
- (2011) M. R. Domingo-Sananes et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil
- (2010) Hiroshi Hirai et al. CANCER BIOLOGY & THERAPY
- Protein kinase signaling networks in cancer
- (2010) John Brognard et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Human kinome drug discovery and the emerging importance of atypical allosteric inhibitors
- (2010) Richard M Eglen et al. Expert Opinion on Drug Discovery
- Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis
- (2010) Olivier Gavet et al. JOURNAL OF CELL BIOLOGY
- Positive-feedback loops in cell cycle progression
- (2009) Joseph R. Pomerening FEBS LETTERS
- The decision to enter mitosis: feedback and redundancy in the mitotic entry network
- (2009) Arne Lindqvist et al. JOURNAL OF CELL BIOLOGY
- Through the “Gatekeeper Door”: Exploiting the Active Kinase Conformation
- (2009) Fabio Zuccotto et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor
- (2009) Shinji Mizuarai et al. Molecular Cancer
- Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
- (2009) H. Hirai et al. MOLECULAR CANCER THERAPEUTICS
- Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
- (2009) A Satyanarayana et al. ONCOGENE
- G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer
- (2008) N Bucher et al. BRITISH JOURNAL OF CANCER
- Uncovering mechanisms of bistability in biological systems
- (2008) Joseph R Pomerening CURRENT OPINION IN BIOTECHNOLOGY
- Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit
- (2008) Hiroyuki Nakajima et al. JOURNAL OF CELL BIOLOGY
- Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF
- (2008) Joseph R. Pomerening et al. MOLECULAR BIOLOGY OF THE CELL
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