Fucoidan ameliorates pancreatic β-cell death and impaired insulin synthesis in streptozotocin-treated β cells and mice via a Sirt-1-dependent manner

Exenatide exerts direct protective effects on endothelial cells through the AMPK/Akt/eNOS pathway in a GLP-1 receptor-dependent manner

(2016) Rui Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism

(2016) Francesco Andreozzi et al.   Journal of Translational Medicine

The neuroprotective effects of the anti-diabetic drug linagliptin against Aß-induced neurotoxicity

(2016) Chien-Ning Huang et al.   Neural Regeneration Research

Modulation of SIRT1-Foxo1 Signaling axis by Resveratrol: Implications in Skeletal Muscle Aging and Insulin Resistance

(2015) Thomas K. Sin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Therapies from Fucoidan: An Update

(2015) Janet Fitton et al.   Marine Drugs

Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia

(2015) Meng-Chuan Chen et al.   Marine Drugs

AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation

(2015) Chunmei Chang et al.   MOLECULAR CELL

The Protective Effect of Fucoidan in Rats with Streptozotocin-Induced Diabetic Nephropathy

(2014) Jing Wang et al.   Marine Drugs

SIRT1 Deacetylates FOXA2 and Is Critical for Pdx1 Transcription and β-Cell Formation

(2013) Rui-Hong Wang et al.   International Journal of Biological Sciences

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

(2013) Munehiro Kitada et al.   Diabetes & Metabolism Journal

Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction

(2012) Ling Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Regulation of FOXO protein stability via ubiquitination and proteasome degradation

(2011) Haojie Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel GLP-1 receptor agonists for diabetes

(2011) Alan J Garber   EXPERT OPINION ON INVESTIGATIONAL DRUGS

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

(2011) Goodarz Danaei et al.   LANCET

Two incretin hormones GLP-1 and GIP: Comparison of their actions in insulin secretion and β cell preservation

(2011) Daisuke Yabe et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy

(2011) N. R. Sundaresan et al.   Science Signaling

The diverse functions of GAPDH: Views from different subcellular compartments

(2010) Carlos Tristan et al.   CELLULAR SIGNALLING

Transcription factors involved in glucose-stimulated insulin secretion of pancreatic beta cells

(2009) Shiying Shao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY

Overexpression of SIRT1 Protects Pancreatic  -Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor- B Signaling Pathway

(2008) J.-H. Lee et al.   DIABETES

PDX-1 and MafA Play a Crucial Role in Pancreatic β-Cell Differentiation and Maintenance of Mature β-Cell Function

(2008) Hideaki KANETO et al.   ENDOCRINE JOURNAL

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

(2008) N. Gao et al.   GENES & DEVELOPMENT

Preservation of β-cell function by targeting β-cell mass

(2008) E DEKONING et al.   TRENDS IN PHARMACOLOGICAL SCIENCES