Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

The broad-spectrum chemokine inhibitor NR58-3.14.3 modulates macrophage-mediated inflammation in the diseased retina

(2016) Nilisha Fernando et al.   Journal of Neuroinflammation

Interleukin 1α and the inflammatory process

(2016) Nelson C Di Paolo et al.   NATURE IMMUNOLOGY

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

(2016) Chiara M Eandi et al.   eLife

CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

(2016) Kyoko Tomita et al.   Scientific Reports

IL-1β reciprocally regulates chemokine and insulin secretion in pancreatic β-cells via NF-κB

(2015) Susan J. Burke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

CXCL10 induces the recruitment of monocyte-derived macrophages into kidney, which aggravate puromycin aminonucleoside nephrosis

(2015) D. Petrovic-Djergovic et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

(2015) L. Zhao et al.   EMBO Molecular Medicine

IL-1β Induces IL-6 production in retinal Müller cells predominantly through the activation of P38 MAPK/NF-κB signaling pathway

(2015) Xiufen Liu et al.   EXPERIMENTAL CELL RESEARCH

Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium

(2015) Matt Rutar et al.   Journal of Neuroinflammation

Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1  Secretion and Photoreceptor Neurodegeneration

(2015) S. J. Hu et al.   JOURNAL OF NEUROSCIENCE

Interleukin-1β Level Is Increased in Vitreous of Patients with Neovascular Age-Related Macular Degeneration (nAMD) and Polypoidal Choroidal Vasculopathy (PCV)

(2015) Min Zhao et al.   PLoS One

Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death

(2015) K Kataoka et al.   Cell Death & Disease

Spatiotemporal Cadence of Macrophage Polarisation in a Model of Light-Induced Retinal Degeneration

(2015) Haihan Jiao et al.   PLoS One

Cutting Edge: IL-1α Is a Crucial Danger Signal Triggering Acute Myocardial Inflammation during Myocardial Infarction

(2014) Jérôme Lugrin et al.   JOURNAL OF IMMUNOLOGY

Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina

(2014) Matt Rutar et al.   PLoS One

CCR2+monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation inCx3cr1deficient mice

(2013) Florian Sennlaub et al.   EMBO Molecular Medicine

Protective Role of Commensals against Clostridium difficile Infection via an IL-1 -Mediated Positive-Feedback Loop

(2012) M. Hasegawa et al.   JOURNAL OF IMMUNOLOGY

Regulation of the CCL2 Gene in Pancreatic β-Cells by IL-1β and Glucocorticoids: Role of MKP-1

(2012) Susan J. Burke et al.   PLoS One

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks

(2012) Aaron M Newman et al.   Genome Medicine

Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration

(2011) Sophie Lavalette et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

IL-1  and IL-1  Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

(2011) P. Rider et al.   JOURNAL OF IMMUNOLOGY

Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina

(2011) Minhua Wang et al.   Journal of Neuroinflammation

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Brief Exposure to Damaging Light Causes Focal Recruitment of Macrophages, and Long-Term Destabilization of Photoreceptors in the Albino Rat Retina

(2010) Matt Rutar et al.   CURRENT EYE RESEARCH

Chemokines and Chemokine Receptors: Standing at the Crossroads of Immunobiology and Neurobiology

(2009) Richard M. Ransohoff   IMMUNITY

Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

(2009) Wenxin Ma et al.   PLoS One