Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Rod-Derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis

(2015) Najate Aït-Ali et al.   CELL

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

(2015) O. Levy et al.   EMBO Molecular Medicine

Abundance of infiltrating CD163+ cells in the retina of postmortem eyes with dry and neovascular age-related macular degeneration

(2015) Eleonora M. Lad et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1  Secretion and Photoreceptor Neurodegeneration

(2015) S. J. Hu et al.   JOURNAL OF NEUROSCIENCE

CX3CL1 (Fractalkine) Protein Expression in Normal and Degenerating Mouse Retina: In Vivo Studies

(2014) Marina Zieger et al.   PLoS One

Geographic Atrophy

(2014) Alan C. Bird et al.   JAMA Ophthalmology

CCR2+monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation inCx3cr1deficient mice

(2013) Florian Sennlaub et al.   EMBO Molecular Medicine

Comment on “Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration” by Luhmann et al. (Exp. Eye Res. 2013; 107: 80.doi: 10.1016)

(2013) Christophe Combadière et al.   EXPERIMENTAL EYE RESEARCH

Adaptive Optics Imaging of Geographic Atrophy

(2013) K. Gocho et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal

(2013) Hideo Kohno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration

(2013) Matt Rutar et al.   Journal of Neuroinflammation

Photoreceptor Impairment and Restoration on Optical Coherence Tomographic Image

(2013) Yoshinori Mitamura et al.   Journal of Ophthalmology

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

(2012) M. Suzuki et al.   JOURNAL OF CELL SCIENCE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration

(2011) Sophie Lavalette et al.   AMERICAN JOURNAL OF PATHOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

(2009) Wenxin Ma et al.   PLoS One

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Role of the chemokine receptor CX3CR1 in the mobilization of phagocytic retinal microglial cells

(2008) William Raoul et al.   JOURNAL OF NEUROIMMUNOLOGY

Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa

(2008) Claudio Punzo et al.   NATURE NEUROSCIENCE