Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin

Evolution and diversity of cadherins and catenins

(2017) Ismail Sahin Gul et al.   EXPERIMENTAL CELL RESEARCH

APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission

(2017) Sandra Schilling et al.   JOURNAL OF NEUROSCIENCE

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

(2017) Xia Hu et al.   Frontiers in Neuroanatomy

LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State

(2017) Uta-Mareike Herr et al.   Frontiers in Molecular Neuroscience

Functional Roles of the Interaction of APP and Lipoprotein Receptors

(2017) Theresa Pohlkamp et al.   Frontiers in Molecular Neuroscience

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry

(2017) Jakob V. Larsen et al.   Jove-Journal of Visualized Experiments

Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease

(2016) Olav M. Andersen et al.   ACTA NEUROPATHOLOGICA

Conventional kinesin: Biochemical heterogeneity and functional implications in health and disease

(2016) Gerardo Morfini et al.   BRAIN RESEARCH BULLETIN

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

(2016) Ragna Sannerud et al.   CELL

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease

(2016) Claudio Villegas-Llerena et al.   CURRENT OPINION IN NEUROBIOLOGY

Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells

(2016) Stine C. Klinger et al.   FEBS Journal

Do Microglia Default on Network Maintenance in Alzheimer’s Disease?

(2016) Katherine A. Southam et al.   JOURNAL OF ALZHEIMERS DISEASE

A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer’s Disease

(2016) Carl-Henrik Andersson et al.   JOURNAL OF ALZHEIMERS DISEASE

Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments

(2016) Xavier Meckler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Greek Tragedy: The Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis

(2016) Robert J. Andrew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein

(2016) Timothy Y. Huang et al.   JOURNAL OF NEUROSCIENCE

Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover

(2016) Jakob Vejby Larsen et al.   MOLECULAR AND CELLULAR BIOLOGY

Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site

(2016) Caroline Schönherr et al.   Molecular Neurodegeneration

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Control of neuronal synapse specification by a highly dedicated alternative splicing program

(2016) L. Traunmuller et al.   SCIENCE

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

(2015) Felix Jäckle et al.   BIOCHEMICAL JOURNAL

New tricks from an old dog: Another synaptotoxic fragment from APP

(2015) Sheue-Houy Tyan et al.   CELL RESEARCH

Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

(2015) Steffen E. Storck et al.   JOURNAL OF CLINICAL INVESTIGATION

SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport

(2015) Guido Hermey et al.   JOURNAL OF NEUROCHEMISTRY

Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain

(2015) S. B. Dumanis et al.   JOURNAL OF NEUROSCIENCE

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

(2015) Michael Willem et al.   NATURE

Structural basis for amyloidogenic peptide recognition by sorLA

(2015) Yu Kitago et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors

(2015) Jeffrey N. Savas et al.   NEURON

Microglial Malfunction: The Third Rail in the Development of Alzheimer's Disease

(2015) Siddhita D. Mhatre et al.   TRENDS IN NEUROSCIENCES

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease

(2015) Zhentao Zhang et al.   Nature Communications

Structural basis for amyloidogenic peptide recognition by sorLA

(2015) Yu Kitago et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Calsyntenin-3 Molecular Architecture and Interaction with Neurexin 1α

(2014) Zhuoyang Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SorLA Complement-type Repeat Domains Protect the Amyloid Precursor Protein against Processing

(2014) Arnela Mehmedbasic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CELSR2–PSRC1–SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort

(2014) Prathima Arvind et al.   Journal of Cardiology

Spatiotemporal expression analysis of the growth factor receptor SorCS3

(2014) Sandra Oetjen et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Amyloid Precursor Protein Dimerization and Synaptogenic Function Depend on Copper Binding to the Growth Factor-Like Domain

(2014) F. Baumkotter et al.   JOURNAL OF NEUROSCIENCE

Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport

(2014) Kyoko Chiba et al.   MOLECULAR BIOLOGY OF THE CELL

More than Cholesterol Transporters: Lipoprotein Receptors in CNS Function and Neurodegeneration

(2014) Courtney Lane-Donovan et al.   NEURON

Lysosomal Sorting of Amyloid-  by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation

(2014) S. Caglayan et al.   Science Translational Medicine

Shedding of APP limits its synaptogenic activity and cell adhesion properties

(2014) Ronny Stahl et al.   Frontiers in Cellular Neuroscience

Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins

(2014) Ji Won Um et al.   Cell Reports

The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease

(2014) Takahisa Kanekiyo et al.   Frontiers in Aging Neuroscience

Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

(2014) Gary W. Beecham et al.   PLoS Genetics

Calsyntenin-3 C-Terminal Fragment Accumulates in Dystrophic Neurites Surrounding Aβ Plaques in Tg2576 Mouse and Alzheimer Disease Brains

(2013) Yoko Uchida et al.   AMERICAN JOURNAL OF PATHOLOGY

Human sorCS1 binds sortilin and hampers its cellular functions

(2013) Jakob Vejby Larsen et al.   BIOCHEMICAL JOURNAL

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

(2013) Alessio Vagnoni et al.   HUMAN MOLECULAR GENETICS

A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm

(2013) Gregory T. Jones et al.   HUMAN MOLECULAR GENETICS

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

(2013) Meng-meng Fu et al.   JOURNAL OF CELL BIOLOGY

Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease

(2013) T. E. Willnow et al.   JOURNAL OF CELL SCIENCE

A genome-wide association study of a coronary artery disease risk variant

(2013) Ji-Young Lee et al.   JOURNAL OF HUMAN GENETICS

Amyloid beta1-42(Aβ42) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway

(2013) Khalil Saadipour et al.   JOURNAL OF NEUROCHEMISTRY

The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-  Peptide in the Brain

(2013) A.-S. Carlo et al.   JOURNAL OF NEUROSCIENCE

Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein

(2013) C. Gustafsen et al.   JOURNAL OF NEUROSCIENCE

SORLA-Dependent and -Independent Functions for PACS1 in Control of Amyloidogenic Processes

(2013) T. Burgert et al.   MOLECULAR AND CELLULAR BIOLOGY

Activity-Induced Convergence of APP and BACE-1 in Acidic Microdomains via an Endocytosis-Dependent Pathway

(2013) Utpal Das et al.   NEURON

The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development

(2013) Katherine L. Pettem et al.   NEURON

No association of SORT1 gene polymorphism with sporadic Alzheimer’s disease in the Chinese Han population

(2013) Fan Zeng et al.   NEUROREPORT

The Intracellular Domain of Sortilin Interacts with Amyloid Precursor Protein and Regulates Its Lysosomal and Lipid Raft Trafficking

(2013) Miao Yang et al.   PLoS One

The Genetic Variation of SORCS1 Is Associated with Late-Onset Alzheimer’s Disease in Chinese Han Population

(2013) Wei Xu et al.   PLoS One

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

(2013) D. M. Holtzman et al.   Cold Spring Harbor Perspectives in Medicine

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

(2013) C Reitz et al.   Translational Psychiatry

Proteomic Changes in Cerebrospinal Fluid of Presymptomatic and Affected Persons Carrying Familial Alzheimer Disease Mutations

(2012) John M. Ringman   ARCHIVES OF NEUROLOGY

SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population

(2012) Hui-Fu Wang et al.   BRAIN RESEARCH

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates A  production

(2012) A. Vagnoni et al.   HUMAN MOLECULAR GENETICS

The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species

(2012) Jessica Bien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

(2012) A. W. Fjorback et al.   JOURNAL OF NEUROSCIENCE

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

(2012) Jeremy H. Herskowitz et al.   MOLECULAR BIOLOGY OF THE CELL

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

(2012) J-C Lambert et al.   MOLECULAR PSYCHIATRY

Advances in understanding the molecular basis of frontotemporal dementia

(2012) Rosa Rademakers et al.   Nature Reviews Neurology

Constitutive Cleavage of the Single-Pass Transmembrane Protein Alcadeinα Prevents Aberrant Peripheral Retention of Kinesin-1

(2012) Chiaki Maruta et al.   PLoS One

Association of Genetic Variants Influencing Lipid Levels with Coronary Artery Disease in Japanese Individuals

(2012) Fumihiko Takeuchi et al.   PLoS One

Structural basis for the sheddase function of human meprin   metalloproteinase at the plasma membrane

(2012) J. L. Arolas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor

(2012) M. Prudencio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Do GGA Adaptors Bind Internal DXXLL Motifs?

(2012) Balraj Doray et al.   TRAFFIC

Molecular consequences of amyloid precursor protein and presenilin mutations causing autosomal-dominant Alzheimer's disease

(2012) Sascha Weggen et al.   Alzheimers Research & Therapy

LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE – carrying lipoproteins

(2011) J. Haas et al.   ATHEROSCLEROSIS

Genetic Risk Score and Risk of Myocardial Infarction in Hispanics

(2011) Lu Qi et al.   CIRCULATION

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

(2011) Vanessa Schmidt et al.   EMBO JOURNAL

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

(2011) Aspasia Angelakopoulou et al.   EUROPEAN HEART JOURNAL

Phosphorylation of LRP1 regulates the interaction with Fe65

(2011) Wilfried Klug et al.   FEBS LETTERS

Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragmentsin Vivo

(2011) Tamara Jefferson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Revisited

(2011) Qinxi Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal Brain-derived Neurotrophic Factor Is Synthesized in Excess, with Levels Regulated by Sortilin-mediated Trafficking and Lysosomal Degradation

(2011) Sarah Felice Evans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BACE1 Retrograde Trafficking Is Uniquely Regulated by the Cytoplasmic Domain of Sortilin

(2011) Gina M. Finan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology

(2011) Lei Wen et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1

(2011) A. Vagnoni et al.   JOURNAL OF CELL SCIENCE

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking

(2011) S. C. Klinger et al.   JOURNAL OF CELL SCIENCE

Potential Mechanisms of Progranulin-deficient FTLD

(2011) Michael Emmerson Ward et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing

(2011) Stefan F. Lichtenthaler et al.   JOURNAL OF NEUROCHEMISTRY

Sorting nexins provide diversity for retromer-dependent trafficking events

(2011) Peter J. Cullen et al.   NATURE CELL BIOLOGY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

(2011) Magdalini Polymenidou et al.   NATURE NEUROSCIENCE

C-Terminus of Progranulin Interacts with the Beta-Propeller Region of Sortilin to Regulate Progranulin Trafficking

(2011) Yanqiu Zheng et al.   PLoS One

Impact of Genetic Variation in SORCS1 on Memory Retention

(2011) Christiane Reitz et al.   PLoS One

The role of lipoprotein receptors on the physiological function of APP

(2011) Timo Wagner et al.   EXPERIMENTAL BRAIN RESEARCH

Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells

(2011) Silke Brunholz et al.   EXPERIMENTAL BRAIN RESEARCH

Genome-wide Screen Identifies rs646776 near Sortilin as a Regulator of Progranulin Levels in Human Plasma

(2010) Minerva M. Carrasquillo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and alzheimer's disease: Evidence for γ-secretase dysfunction

(2010) Saori Hata et al.   ANNALS OF NEUROLOGY

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

(2010) Christiane Reitz et al.   ANNALS OF NEUROLOGY

Lipoprotein receptors – an evolutionarily ancient multifunctional receptor family

(2010) Marco Dieckmann et al.   BIOLOGICAL CHEMISTRY

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

The role of low-density receptor-related protein 1 (LRP1) as a competitive substrate of the amyloid precursor protein (APP) for BACE1

(2010) Bjoern von Einem et al.   EXPERIMENTAL NEUROLOGY

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk

(2010) Chandra A. Reynolds et al.   HUMAN MOLECULAR GENETICS

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

(2010) Benjamin E.L. Lauffer et al.   JOURNAL OF CELL BIOLOGY

Alpha-secretase in Alzheimer’s disease: molecular identity, regulation and therapeutic potential

(2010) Stefan F. Lichtenthaler   JOURNAL OF NEUROCHEMISTRY

Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-  Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex

(2010) R. F. Lane et al.   JOURNAL OF NEUROSCIENCE

Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor   Heterodimer

(2010) J. V. Larsen et al.   MOLECULAR AND CELLULAR BIOLOGY

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

(2010) Thorsten Pflanzner et al.   NEUROBIOLOGY OF AGING

Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin

(2010) Fenghua Hu et al.   NEURON

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease

(2010) Elliott J. Mufson et al.   NEUROSCIENCE LETTERS

Molecular characterization of a trafficking organelle: Dissecting the axonal paths of calsyntenin-1 transport vesicles

(2010) Martin Steuble et al.   PROTEOMICS

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis

(2009) Sara M. Reekmans et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose

(2009) A. D. Paterson et al.   DIABETES

Alcadein Cleavages by Amyloid β-Precursor Protein (APP) α- and γ-Secretases Generate Small Peptides, p3-Alcs, Indicating Alzheimer Disease-related γ-Secretase Dysfunction

(2009) Saori Hata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

 -Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of  -Carboxyl Terminal Fragment

(2009) M. Takami et al.   JOURNAL OF NEUROSCIENCE

APP Anterograde Transport Requires Rab3A GTPase Activity for Assembly of the Transport Vesicle

(2009) A. Szodorai et al.   JOURNAL OF NEUROSCIENCE

The  -Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

(2009) R. Vassar et al.   JOURNAL OF NEUROSCIENCE

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain

(2009) Esben M Quistgaard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Calsyntenins Mediate TGN Exit of APP in a Kinesin-1-Dependent Manner

(2009) Alexander Ludwig et al.   TRAFFIC

Sortilin mediates the lysosomal targeting of cathepsins D and H

(2008) Maryssa Canuel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conventional Kinesin Holoenzymes Are Composed of Heavy and Light Chain Homodimers†

(2008) Scott R. DeBoer et al.   BIOCHEMISTRY

Functional Role of Lipoprotein Receptors in Alzheimers Disease

(2008) Claus Pietrzik et al.   Current Alzheimer Research

Genomic convergence to identify candidate genes for Alzheimer Disease on chromosome 10

(2008) Xueying Liang et al.   HUMAN MUTATION

Endocytosis of Apolipoprotein A-V by Members of the Low Density Lipoprotein Receptor and the Vps10p Domain Receptor Families

(2008) Stefan K. Nilsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

(2008) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons

(2008) A. Schneider et al.   JOURNAL OF NEUROSCIENCE

LRP1 modulates APP trafficking along early compartments of the secretory pathway

(2008) Elaine Waldron et al.   NEUROBIOLOGY OF DISEASE

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNX1 Defines an Early Endosomal Recycling Exit for Sortilin and Mannose 6-Phosphate Receptors

(2008) Muriel Mari et al.   TRAFFIC

Different Motifs Regulate Trafficking of SorCS1 Isoforms

(2008) Morten S. Nielsen et al.   TRAFFIC

Mint3/X11γ Is an ADP-Ribosylation Factor-dependent Adaptor that Regulates the Traffic of the Alzheimer's Precursor Protein from the Trans-Golgi Network

(2007) Punya Shrivastava-Ranjan et al.   MOLECULAR BIOLOGY OF THE CELL