Cerebrovascular Angiogenic Reprogramming upon LRP1 Repression: Impact on Sphingosine-1-Phosphate-Mediated Signaling in Brain Endothelial Cell Chemotactism

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Role of scavenger receptors in peptide-based delivery of plasmid DNA across a blood–brain barrier model

(2016) Artita Srimanee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lysophospholipid receptors in drug discovery

(2015) Yasuyuki Kihara et al.   EXPERIMENTAL CELL RESEARCH

Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

Metabolic reprogramming in glioblastoma: the influence of cancer metabolism on epigenetics and unanswered questions

(2015) Sameer Agnihotri et al.   NEURO-ONCOLOGY

C/EBPβ and C/EBPδ transcription factors: Basic biology and roles in the CNS

(2015) Marta Pulido-Salgado et al.   PROGRESS IN NEUROBIOLOGY

PAI-1 modulates cell migration in a LRP1-dependent manner via β-catenin and ERK1/2

(2015) Nina Kozlova et al.   THROMBOSIS AND HAEMOSTASIS

Sphingosine 1-phosphate signaling at the blood–brain barrier

(2015) Briana Prager et al.   TRENDS IN MOLECULAR MEDICINE

Signaling Networks that Regulate Cell Migration

(2015) Peter Devreotes et al.   Cold Spring Harbor Perspectives in Biology

Hypoxia Augments Outgrowth Endothelial Cell (OEC) Sprouting and Directed Migration in Response to Sphingosine-1-Phosphate (S1P)

(2015) Priscilla A. Williams et al.   PLoS One

The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development

(2014) C. Nakajima et al.   DEVELOPMENT

Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte

(2014) Yoko Hashimoto et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ensembl 2015

(2014) Fiona Cunningham et al.   NUCLEIC ACIDS RESEARCH

Regulation of LRP-1 expression: Make the point

(2014) H. Emonard et al.   PATHOLOGIE BIOLOGIE

The role of sphingosine kinase isoforms and receptors S1P1, S1P2, S1P3, and S1P5 in primary, secondary, and recurrent glioblastomas

(2014) Karl Quint et al.   TUMOR BIOLOGY

A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy

(2014) J Noack et al.   Cell Death & Disease

Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy

(2014) Masayuki Nagahashi et al.   Biomed Research International

The Warburg effect then and now: From cancer to inflammatory diseases

(2013) Eva M. Palsson-McDermott et al.   BIOESSAYS

Epigallocatechin Gallate Targeting of Membrane Type 1 Matrix Metalloproteinase-mediated Src and Janus Kinase/Signal Transducers and Activators of Transcription 3 Signaling Inhibits Transcription of Colony-stimulating Factors 2 and 3 in Mesenchymal Stromal Cells

(2013) Alain Zgheib et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Inducible Factors and Sphingosine 1-Phosphate Signaling

(2012) Olivier Cuvillier et al.   Anti-Cancer Agents in Medicinal Chemistry

Sphingosine 1-phosphate signalling in cancer

(2012) Nigel J. Pyne et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the Bmp System in Endothelial Cells and in Angiogenesis

(2012) Xinchun Pi et al.   CIRCULATION RESEARCH

Cancer metabolism: current perspectives and future directions

(2012) C Muñoz-Pinedo et al.   Cell Death & Disease

Hypoxia Stimulates Low-Density Lipoprotein Receptor–Related Protein-1 Expression Through Hypoxia-Inducible Factor-1α in Human Vascular Smooth Muscle Cells

(2011) Jose Castellano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function

(2011) Charlotte Selvais et al.   FASEB JOURNAL

Molecular Basis for the Interaction of Low Density Lipoprotein Receptor-related Protein 1 (LRP1) with Integrin αMβ2

(2011) Sripriya Ranganathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Role of FAK in S1P-regulated endothelial permeability

(2011) Patrick Belvitch et al.   MICROVASCULAR RESEARCH

Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro

(2010) Viviana Anelli et al.   FASEB JOURNAL

Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Forms a Signaling Complex with Platelet-derived Growth Factor Receptor-β in Endosomes and Regulates Activation of the MAPK Pathway

(2010) Selen Catania Muratoglu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4

(2010) A. Jen et al.   JOURNAL OF CELL SCIENCE

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Modulation of invasive properties of CD133(+) glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling

(2009) Borhane Annabi et al.   MOLECULAR CARCINOGENESIS

Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

(2009) Reinhard Gabathuler   NEUROBIOLOGY OF DISEASE

Silencing of the MT1-MMP/ G6PT axis suppresses calcium mobilization by sphingosine-1-phosphate in glioblastoma cells

(2008) Simon Fortier et al.   FEBS LETTERS

Pertussis toxin induces angiogenesis in brain microvascular endothelial cells

(2008) Changming Lu et al.   JOURNAL OF NEUROSCIENCE RESEARCH