The role of sphingosine kinase isoforms and receptors S1P1, S1P2, S1P3, and S1P5 in primary, secondary, and recurrent glioblastomas

A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis

(2013) Hazem J. Abuhusain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokine Patterns in Brain Tumour Progression

(2013) Radu Albulescu et al.   MEDIATORS OF INFLAMMATION

Inhibition of sphingosine kinase 1 suppresses proliferation of glioma cells under hypoxia by attenuating activity of extracellular signal-regulated kinase

(2012) H. Zhang et al.   CELL PROLIFERATION

Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma

(2012) A. Estrada-Bernal et al.   NEURO-ONCOLOGY

Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model

(2011) Yoanne Mousseau et al.   BREAST CANCER RESEARCH AND TREATMENT

Targeting inflammation-induced transcription factor activation: an open frontier for glioma therapy

(2011) Ellora Sen   DRUG DISCOVERY TODAY

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro

(2010) Viviana Anelli et al.   FASEB JOURNAL

Cellular Localization of Sphingosine-1-phosphate Receptor 1 Expression in the Human Central Nervous System

(2010) Hirotake Nishimura et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The role of sphingosine kinase-1 in EGFRvIII-regulated growth and survival of glioblastoma cells

(2010) Adriana Estrada-Bernal et al.   JOURNAL OF NEURO-ONCOLOGY

Induction of Donor-Specific Tolerance Using Superagonistic CD28 Antibody in Rat Renal Allografts: Regulatory T-Cell Expansion Before Engraftment May Be Important

(2010) Haruhito Azuma et al.   TRANSPLANTATION

A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells

(2009) Meryem Bektas et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts

(2009) D. Kapitonov et al.   CANCER RESEARCH

Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug

(2009) J. Guillermet-Guibert et al.   MOLECULAR CANCER THERAPEUTICS

Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes

(2008) M. V. Shah et al.   BLOOD

FTY720 Induces Apoptosis in Hepatocellular Carcinoma Cells through Activation of Protein Kinase C   Signaling

(2008) J.-H. Hung et al.   CANCER RESEARCH

Clinical Significance of Sphingosine Kinase-1 Expression in Human Astrocytomas Progression and Overall Patient Survival

(2008) J. Li et al.   CLINICAL CANCER RESEARCH

Phosphatidylinositol 3-Kinase/AKT Pathway Regulates the Endoplasmic Reticulum to Golgi Traffic of Ceramide in Glioma Cells

(2008) Paola Giussani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Central nervous system-directed effects of FTY720 (fingolimod)

(2008) Veronique E. Miron et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FTY720 modulates human oligodendrocyte progenitor process extension and survival

(2007) Veronique E. Miron et al.   ANNALS OF NEUROLOGY