A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici

Establishment of CRISPR/Cas9 in Alternaria alternata

(2017) Maximilian Wenderoth et al.   FUNGAL GENETICS AND BIOLOGY

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

(2016) Tonia Akoumianaki et al.   Cell Host & Microbe

Tet-on, or Tet-off, that is the question: Advanced conditional gene expression in Aspergillus

(2016) Franziska Wanka et al.   FUNGAL GENETICS AND BIOLOGY

Characterization of the product of a nonribosomal peptide synthetase-like (NRPS-like) gene using the doxycycline dependent Tet-on system in Aspergillus terreus

(2016) Wei-Wen Sun et al.   FUNGAL GENETICS AND BIOLOGY

Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases

(2016) Carly Bond et al.   FUNGAL GENETICS AND BIOLOGY

Polyketide Production of Pestaloficiols and Macrodiolide Ficiolides Revealed by Manipulations of Epigenetic Regulators in an Endophytic Fungus

(2016) Guangwei Wu et al.   ORGANIC LETTERS

Biosynthetic Pathway of the Reduced Polyketide Product Citreoviridin in Aspergillus terreus var. aureus Revealed by Heterologous Expression in Aspergillus nidulans

(2016) Tzu-Shyang Lin et al.   ORGANIC LETTERS

Subcellular Compartmentalization and Trafficking of the Biosynthetic Machinery for Fungal Melanin

(2016) Srijana Upadhyay et al.   Cell Reports

Development of Genetic Dereplication Strains in Aspergillus nidulans Results in the Discovery of Aspercryptin

(2015) Yi-Ming Chiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fungal artificial chromosomes for mining of the fungal secondary metabolome

(2015) Jin Woo Bok et al.   BMC GENOMICS

Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products

(2015) Xiuna Wang et al.   BMC GENOMICS

Biosynthesis of non-melanin pigment by a divergent polyketide synthase in Metarhizium robertsii

(2015) Yixiong Chen et al.   FUNGAL GENETICS AND BIOLOGY

Melanin is required for the formation of the multi-cellular conidia in the endophytic fungus Pestalotiopsis microspora

(2015) Xi Yu et al.   MICROBIOLOGICAL RESEARCH

DHN melanin biosynthesis in the plant pathogenic fungusBotrytis cinereais based on two developmentally regulated key enzyme (PKS)-encoding genes

(2015) Julia Schumacher   MOLECULAR MICROBIOLOGY

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

(2015) Peter J. Rutledge et al.   NATURE REVIEWS MICROBIOLOGY

Fungal Melanin: What do We Know About Structure?

(2015) Joshua D. Nosanchuk et al.   Frontiers in Microbiology

Biological roles of fungal carotenoids

(2014) Javier Avalos et al.   CURRENT GENETICS

Functional characterization of a veA-dependent polyketide synthase gene in Aspergillus flavus necessary for the synthesis of asparasone, a sclerotium-specific pigment

(2014) Jeffrey W. Cary et al.   FUNGAL GENETICS AND BIOLOGY

Surface Structure Characterization of Aspergillus fumigatus Conidia Mutated in the Melanin Synthesis Pathway and Their Human Cellular Immune Response

(2014) Jagadeesh Bayry et al.   INFECTION AND IMMUNITY

Generation of Complexity in Fungal Terpene Biosynthesis: Discovery of a Multifunctional Cytochrome P450 in the Fumagillin Pathway

(2014) Hsiao-Ching Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Efficient System for Heterologous Expression of Secondary Metabolite Genes in Aspergillus nidulans

(2013) Yi-Ming Chiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Linkage of Oxidative Stress and Mitochondrial Dysfunctions to Spontaneous Culture Degeneration inAspergillus nidulans

(2013) Lin Li et al.   MOLECULAR & CELLULAR PROTEOMICS

Discovery of Cryptic Polyketide Metabolites from Dermatophytes Using Heterologous Expression in Aspergillus nidulans

(2013) Wen-Bing Yin et al.   ACS Synthetic Biology

Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold

(2013) Zengyi Shao et al.   ACS Synthetic Biology

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

(2013) Erwin Berthier et al.   PLoS Pathogens

Tetrahydroxynaphthalene Reductase: Catalytic Properties of an Enzyme Involved in Reductive Asymmetric Naphthol Dearomatization

(2012) Michael A. Schätzle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Breaking the Silence: Protein Stabilization Uncovers Silenced Biosynthetic Gene Clusters in the Fungus Aspergillus nidulans

(2012) Jennifer Gerke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis of Fusarubins Accounts for Pigmentation of Fusarium fujikuroi Perithecia

(2012) Lena Studt et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Characterization of a Fungal Thioesterase Having Claisen Cyclase and Deacetylase Activities in Melanin Biosynthesis

(2012) Anna L. Vagstad et al.   CHEMISTRY & BIOLOGY

Transcription Factor Amr1 Induces Melanin Biosynthesis and Suppresses Virulence in Alternaria brassicicola

(2012) Yangrae Cho et al.   PLoS Pathogens

Synthesis and assembly of fungal melanin

(2011) Helene C. Eisenman et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Unraveling polyketide synthesis in members of the genus Aspergillus

(2010) Yi-Ming Chiang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Melanin Externalization in Candida albicans Depends on Cell Wall Chitin Structures

(2010) Claire A. Walker et al.   EUKARYOTIC CELL

Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia

(2009) Marc Pihet et al.   BMC MICROBIOLOGY