HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes

(2016)   MOLECULES AND CELLS

OASIS: web-based platform for exploring cancer multi-omics data

(2016) Julio Fernandez-Banet et al.   NATURE METHODS

HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24

(2016) W W Teo et al.   ONCOGENE

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

(2016) Bernard Pereira et al.   Nature Communications

Co-delivery of all-trans-retinoic acid and doxorubicin for cancer therapy with synergistic inhibition of cancer stem cells

(2015) Rong Sun et al.   BIOMATERIALS

HOXA5 Counteracts Stem Cell Traits by Inhibiting Wnt Signaling in Colorectal Cancer

(2015) Paloma Ordóñez-Morán et al.   CANCER CELL

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

(2015) Giovanni Ciriello et al.   CELL

Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/ -catenin signaling

(2015) L. S. Carroll et al.   DEVELOPMENT

Embigin, regulated by HOXC8, plays a suppressive role in breast tumorigenesis

(2015) Fengmei Chao et al.   Oncotarget

DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer

(2015) Kevin C. Johnson et al.   Clinical Epigenetics

HOXC8 promotes breast tumorigenesis by transcriptionally facilitating cadherin-11 expression

(2015) Yong Li et al.   Oncotarget

The survival predictive significance of HOXC6 and HOXC8 in esophageal squamous cell carcinoma

(2014) Ya-Bing Du et al.   JOURNAL OF SURGICAL RESEARCH

MethHC: a database of DNA methylation and gene expression in human cancer

(2014) Wei-Yun Huang et al.   NUCLEIC ACIDS RESEARCH

Exploring TCGA Pan-Cancer Data at the UCSC Cancer Genomics Browser

(2013) Melissa S. Cline et al.   Scientific Reports

Targeting the HOX/PBX dimer in breast cancer

(2012) Richard Morgan et al.   BREAST CANCER RESEARCH AND TREATMENT

Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1

(2012) Oscar H. Ocaña et al.   CANCER CELL

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis

(2012) Marta Faryna et al.   FASEB JOURNAL

DLX4 Upregulates TWIST and Enhances Tumor Migration, Invasion and Metastasis

(2012) Lianmei Zhang et al.   International Journal of Biological Sciences

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics

(2012) M. Lohse et al.   NUCLEIC ACIDS RESEARCH

Expression of HOXC8 is inversely related to the progression and metastasis of pancreatic ductal adenocarcinoma

(2011) H Adwan et al.   BRITISH JOURNAL OF CANCER

Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence

(2011) M. J. Fackler et al.   CANCER RESEARCH

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic control of Hox genes during neurogenesis, development, and disease

(2010) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Ratio of miR-196s to HOXC8 Messenger RNA Correlates with Breast Cancer Cell Migration and Metastasis

(2010) Y. Li et al.   CANCER RESEARCH

Retinoid signaling regulates breast cancer stem cell differentiation

(2010) Christophe Ginestier et al.   CELL CYCLE

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

(2010) Sitharthan Kamalakaran et al.   Molecular Oncology

Methylation profiling with a panel of cancer related genes: Association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer

(2010) Jo Anders Rønneberg et al.   Molecular Oncology

Epigenetic regulations in hematopoietic Hox code

(2010) H He et al.   ONCOGENE

Lsh Mediated RNA Polymerase II Stalling at HoxC6 and HoxC8 Involves DNA Methylation

(2010) Yongguang Tao et al.   PLoS One

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Stepwise DNA Methylation Changes Are Linked to Escape from Defined Proliferation Barriers and Mammary Epithelial Cell Immortalization

(2009) P. Novak et al.   CANCER RESEARCH

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

(2009) M. Yu et al.   GENES & DEVELOPMENT

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

(2009) Erica L. McCoy et al.   JOURNAL OF CLINICAL INVESTIGATION

Agglomerative Epigenetic Aberrations Are a Common Event in Human Breast Cancer

(2008) P. Novak et al.   CANCER RESEARCH

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Cell type-specific DNA methylation patterns in the human breast

(2008) N. Bloushtain-Qimron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Marking Prepares the HumanHOXACluster for Activation During Differentiation of Pluripotent Cells

(2008) Stuart P. Atkinson et al.   STEM CELLS