Pharmacology of predatory and defensive venom peptides in cone snails

A novel μ-conotoxin from worm-hunting Conus tessulatus that selectively inhibit rat TTX-resistant sodium currents

(2017) Manyi Yang et al.   TOXICON

Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa

(2016) Helena Safavi-Hemami et al.   MOLECULAR BIOLOGY AND EVOLUTION

The role of defensive ecological interactions in the evolution of conotoxins

(2016) J. R. Prashanth et al.   MOLECULAR ECOLOGY

Intraspecific variations in Conus purpurascens injected venom using LC/MALDI-TOF-MS and LC-ESI-TripleTOF-MS

(2015) Alena M. Rodriguez et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors

(2015) Sean B. Christensen et al.   BIOCHEMICAL PHARMACOLOGY

Prey-Capture Strategies of Fish-Hunting Cone Snails: Behavior, Neurobiology and Evolution

(2015) Baldomero M. Olivera et al.   BRAIN BEHAVIOR AND EVOLUTION

Comparison of the Venom Peptides and Their Expression in Closely RelatedConusSpecies: Insights into Adaptive Post-speciation Evolution ofConusExogenomes

(2015) Neda Barghi et al.   Genome Biology and Evolution

Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus

(2015) S. W. A. Himaya et al.   JOURNAL OF PROTEOME RESEARCH

Insights into the origins of fish hunting in venomous cone snails from studies ofConus tessulatus

(2015) Joseph W. Aman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specialized insulin is used for chemical warfare by fish-hunting cone snails

(2015) Helena Safavi-Hemami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails

(2015) Ai-Hua Jin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Transcriptome and proteome ofConus planorbisidentify the nicotinic receptors as primary target for the defensive venom

(2015) Ai-Hua Jin et al.   PROTEOMICS

Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors

(2015) Shaoqiong Xu et al.   Scientific Reports

Cone snail venomics: from novel biology to novel therapeutics

(2014) Jutty Rajan Prashanth et al.   Future Medicinal Chemistry

One, four or 100 genera? A new classification of the cone snails

(2014) N. Puillandre et al.   JOURNAL OF MOLLUSCAN STUDIES

Molecular phylogeny and evolution of the cone snails (Gastropoda, Conoidea)

(2014) N. Puillandre et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Intraspecific variations in Conus geographus defence-evoked venom and estimation of the human lethal dose

(2014) Sébastien Dutertre et al.   TOXICON

A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity

(2013) Johanna Bernáldez et al.   Marine Drugs

Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels

(2012) Irina Vetter et al.   BIOCHEMICAL PHARMACOLOGY

Structure of the O-Glycosylated Conopeptide CcTx fromConus consorsVenom

(2012) Henry G. Hocking et al.   CHEMISTRY-A EUROPEAN JOURNAL

Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach

(2012) Aude Violette et al.   Journal of Proteomics

Towards an integrated venomics approach for accelerated conopeptide discovery

(2012) Jutty Rajan Prashanth et al.   TOXICON

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

(2011) Q. Kaas et al.   NUCLEIC ACIDS RESEARCH

Intraspecies variability and conopeptide profiling of the injected venom of Conus ermineus

(2010) Jose A. Rivera-Ortiz et al.   PEPTIDES

Dramatic intraspecimen variations within the injected venom of Conus consors: An unsuspected contribution to venom diversity

(2010) Sébastien Dutertre et al.   TOXICON

Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors

(2009) Layla Azam et al.   ACTA PHARMACOLOGICA SINICA

Identification of a novel M-superfamily conotoxin with the ability to enhance tetrodotoxin sensitive sodium currents

(2009) Lei Wang et al.   ARCHIVES OF TOXICOLOGY

Novel αD-Conopeptides and Their Precursors Identified by cDNA Cloning Define the D-Conotoxin Superfamily†‡

(2009) Marion L. Loughnan et al.   BIOCHEMISTRY

A Novel Conus Snail Polypeptide Causes Excitotoxicity by Blocking Desensitization of AMPA Receptors

(2009) Craig S. Walker et al.   CURRENT BIOLOGY

Tyrosine-rich Conopeptides Affect Voltage-gated K+Channels

(2008) Julita S. Imperial et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus

(2008) Mandë Holford et al.   TOXICON