RNA-sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells

(2017) Pol Gimenez-Xavier et al.   MOLECULAR CANCER THERAPEUTICS

Ferulic acid reverses ABCB1-mediated paclitaxel resistance in MDR cell lines

(2016) Ganesan Muthusamy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells

(2016) J. R. Ribeiro et al.   Journal of Ovarian Research

Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases

(2016) Fei Lu et al.   Biology Open

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

(2015) Jun He et al.   Autophagy

The expanding implications of polyploidy

(2015) Kevin P. Schoenfelder et al.   JOURNAL OF CELL BIOLOGY

Nedaplatin plus docetaxel versus cisplatin plus docetaxel for advanced or relapsed squamous cell carcinoma of the lung (WJOG5208L): a randomised, open-label, phase 3 trial

(2015) Takehito Shukuya et al.   LANCET ONCOLOGY

A phase I study of adjuvant intensity-modulated radiotherapy with concurrent paclitaxel and cisplatin for cervical cancer patients with high risk factors

(2015) Pei Shu et al.   MEDICAL ONCOLOGY

SILAC-based quantitative proteomics identified lysosome as a fast response target to PDT agent Gd-N induced oxidative stress in human ovarian cancer IGROV1 cells

(2015) Dandan Qi et al.   Molecular BioSystems

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance

(2015) P Khongkow et al.   ONCOGENE

RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance

(2015) D. T. Miyamoto et al.   SCIENCE

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

(2015) Stine Ninel Hansen et al.   TUMOR BIOLOGY

Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer

(2015) Yeonjoo Jung et al.   Oncotarget

High Id1 expression, a generally negative prognostic factor, paradoxically predicts a favorable prognosis for adjuvant paclitaxel plus cisplatin therapy in surgically treated lung cancer patients

(2015) Yu-Jen Cheng et al.   Oncotarget

Long progression-free survival with first-line paclitaxel plus platinum is associated with improved response and progression-free survival with second-line docetaxel in advanced non-small-cell lung cancer

(2014) Eleazar Omar Macedo-Pérez et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Ovarian Cancer-associated Mutations Disable Catalytic Activity of CDK12, a Kinase That Promotes Homologous Recombination Repair and Resistance to Cisplatin and Poly(ADP-ribose) Polymerase Inhibitors

(2014) Poorval M. Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXM1 mediates resistance to docetaxel in gastric cancerviaup-regulating Stathmin

(2014) Xiaoxiao Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9

(2013) Zhuo Dong et al.   CANCER LETTERS

Proteomics of Genetically Engineered Mouse Mammary Tumors Identifies Fatty Acid Metabolism Members as Potential Predictive Markers for Cisplatin Resistance

(2013) Marc Warmoes et al.   MOLECULAR & CELLULAR PROTEOMICS

Generation of cancer stem-like cells through the formation of polyploid giant cancer cells

(2013) S Zhang et al.   ONCOGENE

Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance

(2013) N. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance

(2013) S Wansleben et al.   Cell Death & Disease

Dissecting the phenotypes of Plk1 inhibition in cancer cells using novel kinase inhibitory chemical CBB2001

(2012) Rongfeng Lan et al.   LABORATORY INVESTIGATION

Resistance to Paclitaxel in a Cisplatin-Resistant Ovarian Cancer Cell Line Is Mediated by P-Glycoprotein

(2012) Britta Stordal et al.   PLoS One

Analysis of chemotherapy response programs in ovarian cancers by the next-generation sequencing technologies

(2010) Lihua Cheng et al.   GYNECOLOGIC ONCOLOGY

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

(2008) Pierre-Emmanuel Puig et al.   CELL BIOLOGY INTERNATIONAL