Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract

Effects of the multikinase inhibitors Sorafenib and Regorafenib in PTEN deficient neoplasias

(2016) Cristina Mirantes et al.   EUROPEAN JOURNAL OF CANCER

Experimental models for posterior capsule opacification research

(2016) Ian Michael Wormstone et al.   EXPERIMENTAL EYE RESEARCH

RhoA/ROCK Signaling Regulates TGFβ-Induced Epithelial-Mesenchymal Transition of Lens Epithelial Cells through MRTF-A

(2016) Anna Korol et al.   MOLECULAR MEDICINE

Targeting BCL-2 and ABL/LYN in Philadelphia chromosome–positive acute lymphoblastic leukemia

(2016) Jessica T. Leonard et al.   Science Translational Medicine

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

(2016) Jon M. Carthy et al.   Scientific Reports

Control of fibrotic changes through the synergistic effects of anti-fibronectin antibody and an RGDS-tagged form of the same antibody

(2016) Anil Tiwari et al.   Scientific Reports

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

(2016) Rona R. Ramsay et al.   Frontiers in Neuroscience

Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins

(2015) Katherine H. Schreiber et al.   AGING CELL

Synergistic interaction between the fibroblast growth factor and bone morphogenetic protein signaling pathways in lens cells

(2015) Bruce A. Boswell et al.   MOLECULAR BIOLOGY OF THE CELL

Expression of Cytokines, Chmokines and Growth Factors in Patients Undergoing Cataract Surgery with Femtosecond Laser Pretreatment

(2015) Hui Chen et al.   PLoS One

Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells

(2014) Subhasree Basu et al.   Autophagy

Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition

(2014) Rik Derynck et al.   CURRENT OPINION IN CELL BIOLOGY

The cellular and molecular mechanisms of vertebrate lens development

(2014) A. Cvekl et al.   DEVELOPMENT

The roles of αVintegrins in lens EMT and posterior capsular opacification

(2014) Fahmy A. Mamuya et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TGF- : Duality of Function Between Tumor Prevention and Carcinogenesis

(2014) D. R. Principe et al.   JNCI-Journal of the National Cancer Institute

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Threshold Levels of ABL Tyrosine Kinase Inhibitors Retained in Chronic Myeloid Leukemia Cells Determine Their Commitment to Apoptosis

(2013) T. O'Hare et al.   CANCER RESEARCH

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

TGF- -induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

(2012) S. Lamouille et al.   JOURNAL OF CELL SCIENCE

Primary Cultures of Embryonic Chick Lens Cells as a Model System to Study Lens Gap Junctions and Fiber Cell Differentiation

(2012) Linda S. Musil   JOURNAL OF MEMBRANE BIOLOGY

Sustained-Release Celecoxib from Incubated Acrylic Intraocular Lenses Suppresses Lens Epithelial Cell Growth in an Ex Vivo Model of Posterior Capsule Opacity

(2012) Jennifer L. Davis et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Multi-Target Drugs: The Trend of Drug Research and Development

(2012) Jin-Jian Lu et al.   PLoS One

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

(2011) Wayne W. Chan et al.   CANCER CELL

The ABL Switch Control Inhibitor DCC-2036 Is Active against the Chronic Myeloid Leukemia Mutant BCR-ABLT315I and Exhibits a Narrow Resistance Profile

(2011) C. A. Eide et al.   CANCER RESEARCH

Modern Cataract Surgery: Unfinished Business and Unanswered Questions

(2011) David J. Apple et al.   SURVEY OF OPHTHALMOLOGY

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3

(2010) András Masszi et al.   JOURNAL OF CELL BIOLOGY

Regulation of Lens Gap Junctions by Transforming Growth Factor Beta

(2010) Bruce A. Boswell et al.   MOLECULAR BIOLOGY OF THE CELL

Posterior Capsular Opacification

(2009) Niranjan Awasthi   ARCHIVES OF OPHTHALMOLOGY

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

The TGF-β paradox in human cancer: an update

(2009) Maozhen Tian et al.   Future Oncology

Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis

(2009) Judith A. West-Mays et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Essential role of BMPs in FGF-induced secondary lens fiber differentiation

(2008) Bruce A. Boswell et al.   DEVELOPMENTAL BIOLOGY

Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

(2008) Haotian Zhao et al.   DEVELOPMENTAL BIOLOGY

Upregulation and maintenance of gap junctional communication in lens cells

(2008) Bruce A. Boswell et al.   EXPERIMENTAL EYE RESEARCH

Integrins in lens development and disease

(2008) Janice Walker et al.   EXPERIMENTAL EYE RESEARCH

Posterior capsule opacification

(2008) I. Michael Wormstone et al.   EXPERIMENTAL EYE RESEARCH

Posterior capsulorhexis combined with optic buttonholing: an alternative to standard in-the-bag implantation of sharp-edged intraocular lenses? A critical analysis of 1000 consecutive cases

(2008) R. Menapace   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY