Resveratrol modulates GSH system in C6 astroglial cells through heme oxygenase 1 pathway

Signaling mechanisms underlying the glioprotective effects of resveratrol against mitochondrial dysfunction

(2016) Bruna Bellaver et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Redox-based therapeutics in neurodegenerative disease

(2016) G J McBean et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs

(2016) José Iglesias et al.   MOLECULAR NEUROBIOLOGY

Lifespan and healthspan extension by resveratrol

(2015) Khushwant S. Bhullar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The molecular targets of resveratrol

(2015) Sameer S. Kulkarni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroprotective action of resveratrol

(2015) Stéphane Bastianetto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimer's Disease: The NF-κB Connection

(2015) Upinder Kaur et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Glutathione in Cellular Redox Homeostasis: Association with the Excitatory Amino Acid Carrier 1 (EAAC1)

(2015) Koji Aoyama et al.   MOLECULES

Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release

(2015) Rachit Bakshi et al.   NEUROBIOLOGY OF DISEASE

Gap Junction Intercellular Communication Mediates Ammonia-Induced Neurotoxicity

(2015) Larissa Daniele Bobermin et al.   NEUROTOXICITY RESEARCH

Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF

(2015) Roman Fischer et al.   Oxidative Medicine and Cellular Longevity

Astrocyte physiopathology: At the crossroads of intercellular networking, inflammation and cell death

(2015) Daniela Rossi   PROGRESS IN NEUROBIOLOGY

Ammonia impairs glutamatergic communication in astroglial cells: protective role of resveratrol

(2015) Larissa Daniele Bobermin et al.   TOXICOLOGY IN VITRO

The established and emerging roles of astrocytes and microglia in amyotrophic lateral sclerosis and frontotemporal dementia

(2015) Rowan A. Radford et al.   Frontiers in Cellular Neuroscience

Implications of glial nitric oxide in neurodegenerative diseases

(2015) Jose Enrique Yuste et al.   Frontiers in Cellular Neuroscience

Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS

(2015) Bettina Schreiner et al.   Cell Reports

Effect of resveratrol on mitochondrial function: Implications in parkin-associated familiar Parkinson's disease

(2014) Anna Ferretta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroglia in ageing and disease

(2014) Alexei Verkhratsky et al.   CELL AND TISSUE RESEARCH

Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses

(2014) Chhanda Biswas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guanosine protects C6 astroglial cells against azide-induced oxidative damage: a putative role of heme oxygenase 1

(2014) André Quincozes-Santos et al.   JOURNAL OF NEUROCHEMISTRY

Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity

(2014) Gabriel Olmos et al.   MEDIATORS OF INFLAMMATION

CO Induces Nrf2-Dependent Heme Oxygenase-1 Transcription by Cooperating with Sp1 and c-Jun in Rat Brain Astrocytes

(2014) Pei-Ling Chi et al.   MOLECULAR NEUROBIOLOGY

Glutathione-Dependent Detoxification Processes in Astrocytes

(2014) Ralf Dringen et al.   NEUROCHEMICAL RESEARCH

Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats

(2014) Bruna Bellaver et al.   TOXICOLOGY IN VITRO

Neuroprotective effects of resveratrol in Alzheimer disease pathology

(2014) Shraddha D. Rege et al.   Frontiers in Aging Neuroscience

Heme Oxygenase-1 As a Target for Drug Discovery

(2013) Roberto Motterlini et al.   ANTIOXIDANTS & REDOX SIGNALING

Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response

(2013) Shotaro Nakajima et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Nrf2—an update

(2013) Suryakant K. Niture et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol

(2013) Ning Xia et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Characterization of Adult Rat Astrocyte Cultures

(2013) Débora Guerini Souza et al.   PLoS One

Resveratrol Protects C6 Astrocyte Cell Line against Hydrogen Peroxide-Induced Oxidative Stress through Heme Oxygenase 1

(2013) André Quincozes-Santos et al.   PLoS One

Cardiovascular and renal manifestations of glutathione depletion induced by buthionine sulfoximine

(2012) Félix Vargas et al.   AMERICAN JOURNAL OF HYPERTENSION

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Resveratrol Prevents Ammonia Toxicity in Astroglial Cells

(2012) Larissa Daniele Bobermin et al.   PLoS One

Resveratrol modulates astroglial functions: neuroprotective hypothesis

(2011) André Quincozes-Santos et al.   Annals of the New York Academy of Sciences

The role of glutathione in brain tumor drug resistance

(2011) Donald S. Backos et al.   BIOCHEMICAL PHARMACOLOGY

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Regulation of the System x−C cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures

(2011) Todd Michael Seib et al.   GLIA

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

(2011) C. Escartin et al.   JOURNAL OF NEUROSCIENCE

Resveratrol Protects Rats from Aβ-induced Neurotoxicity by the Reduction of iNOS Expression and Lipid Peroxidation

(2011) Tai-Chun Huang et al.   PLoS One

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Heme oxygenase 1: Another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule

(2010) Stéphane Bastianetto et al.   EXPERIMENTAL NEUROLOGY

Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1

(2010) Yoshihito Sakata et al.   EXPERIMENTAL NEUROLOGY

Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases

(2010) Moonhee Lee et al.   FASEB JOURNAL

Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells

(2010) Kumiko Tanabe et al.   Journal of Neuroinflammation

Haloperidol and clozapine decrease S100B release from glial cells

(2010) J. Steiner et al.   NEUROSCIENCE

Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway

(2009) H-A Park et al.   CELL DEATH AND DIFFERENTIATION

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE