Knockdown of PRMT1 suppresses IL-1β-induced cartilage degradation and inflammatory responses in human chondrocytes through Gli1-mediated Hedgehog signaling pathway

Protein arginine methyltransferase 1 modulates innate immune responses through regulation of peroxisome proliferator-activated receptor γ-dependent macrophage differentiation

(2017) Irina Tikhanovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis

(2016) Neng-Yu Lin et al.   ANNALS OF THE RHEUMATIC DISEASES

Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation

(2016) Yan Wang et al.   CANCER RESEARCH

MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2

(2016) Guoliang Zhang et al.   CELLULAR IMMUNOLOGY

PDGF-BB induces PRMT1 expression through ERK1/2 dependent STAT1 activation and regulates remodeling in primary human lung fibroblasts

(2016) Qingzhu Sun et al.   CELLULAR SIGNALLING

Chondroprotective effects of palmatine on osteoarthritis in vivo and in vitro: A possible mechanism of inhibiting the Wnt/β-catenin and Hedgehog signaling pathways

(2016) Xindie Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Role of Protein Arginine Methyltransferases in Inflammatory Responses

(2016) Ji Hye Kim et al.   MEDIATORS OF INFLAMMATION

Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

(2016) William H. Robinson et al.   Nature Reviews Rheumatology

Protein arginine methyltransferase 1 interacts with Gli1 and regulates its transcriptional activity

(2016) Weizheng Zhou et al.   TUMOR BIOLOGY

The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1

(2016) Yanyan Gao et al.   Scientific Reports

Elevated protein arginine methyltransferase 1 expression regulates fibroblast motility in pulmonary fibrosis

(2015) Dariusz Zakrzewicz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation

(2015) Qingzhu Sun et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-602 and MicroRNA-608 Regulate Sonic Hedgehog Expression via Target Sites in the Coding Region in Human Chondrocytes

(2015) Nahid Akhtar et al.   Arthritis & Rheumatology

Indian Hedgehog, a critical modulator in osteoarthritis, could be a potential therapeutic target for attenuating cartilage degeneration disease

(2014) Jingming Zhou et al.   CONNECTIVE TISSUE RESEARCH

Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo

(2014) Min-Jung Park et al.   JOURNAL OF HEPATOLOGY

A current review of molecular mechanisms regarding osteoarthritis and pain

(2013) Andrew S. Lee et al.   GENE

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Matrix Metalloproteases and Tissue Inhibitors of Metalloproteinases in Medial Plica and Pannus-like Tissue Contribute to Knee Osteoarthritis Progression

(2013) Chih-Chang Yang et al.   PLoS One

Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development

(2013) Y. Hosaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Upregulated Protein Arginine Methyltransferase 1 by IL-4 Increases Eotaxin-1 Expression in Airway Epithelial Cells and Participates in Antigen-Induced Pulmonary Inflammation in Rats

(2012) Q. Sun et al.   JOURNAL OF IMMUNOLOGY

Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage

(2012) F. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review

(2011) D. Pereira et al.   OSTEOARTHRITIS AND CARTILAGE

LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

(2010) Ning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE