From hybridomas to a robust microalgal-based production platform: molecular design of a diatom secreting monoclonal antibodies directed against the Marburg virus nucleoprotein

Antibody Production in Plants and Green Algae

(2016) Vidadi Yusibov et al.   Annual Review of Plant Biology

Algal Cell Factories: Approaches, Applications, and Potentials

(2016) Weiqi Fu et al.   Marine Drugs

A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

(2016) D. Corti et al.   SCIENCE

Development of an antibody capture ELISA using inactivated Ebola Zaire Makona virus

(2015) Verena Krähling et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Biochemical Characterization of Human Anti-Hepatitis B Monoclonal Antibody Produced in the Microalgae Phaeodactylum tricornutum

(2015) Gaëtan Vanier et al.   PLoS One

Efficient expression of full-length antibodies in the cytoplasm of engineered bacteria

(2015) Michael-Paul Robinson et al.   Nature Communications

Photosynthetic biomanufacturing in green algae; production of recombinant proteins for industrial, nutritional, and medical uses

(2014) Beth A. Rasala et al.   PHOTOSYNTHESIS RESEARCH

Algal chloroplast produced camelid VH H antitoxins are capable of neutralizing botulinum neurotoxin

(2014) Daniel J. Barrera et al.   PLANT BIOTECHNOLOGY JOURNAL

Global evaluation of biofuel potential from microalgae

(2014) J. W. Moody et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glyco-engineering for biopharmaceutical production in moss bioreactors

(2014) Eva L. Decker et al.   Frontiers in Plant Science

Protein N-glycosylation in eukaryotic microalgae and its impact on the production of nuclear expressed biopharmaceuticals

(2014) Elodie Mathieu-Rivet et al.   Frontiers in Plant Science

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

Production of anti-cancer immunotoxins in algae: Ribosome inactivating proteins as fusion partners

(2013) Miller Tran et al.   BIOTECHNOLOGY AND BIOENGINEERING

Investigation of monoclonal antibody fragmentation artifacts in non-reducing SDS-PAGE

(2013) Zhiqing C. Zhu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Expression of Recombinant Antibodies

(2013) André Frenzel et al.   Frontiers in Immunology

An engineered diatom acting like a plasma cell secreting human IgG antibodies with high efficiency

(2012) Franziska Hempel et al.   Microbial Cell Factories

Exploiting diversity and synthetic biology for the production of algal biofuels

(2012) D. Ryan Georgianna et al.   NATURE

What's fueling the biotech engine—2011 to 2012

(2012) Saurabh Aggarwal   NATURE BIOTECHNOLOGY

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

(2012) G. G. Olinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of unique immunotoxin cancer therapeutics in algal chloroplasts

(2012) M. Tran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures

(2011) Jianfeng Xu et al.   BIOTECHNOLOGY ADVANCES

Mammalian cells as biopharmaceutical production hosts in the age of omics

(2011) Stefanie Dietmair et al.   Biotechnology Journal

Chlamydomonas reinhardtii as a viable platform for the production of recombinant proteins: current status and perspectives

(2011) Sergio Rosales-Mendoza et al.   PLANT CELL REPORTS

Algae as Protein Factories: Expression of a Human Antibody and the Respective Antigen in the Diatom Phaeodactylum tricornutum

(2011) Franziska Hempel et al.   PLoS One

Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

(2011) L. Zeitlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biodiesel from algae: challenges and prospects

(2010) Stuart A Scott et al.   CURRENT OPINION IN BIOTECHNOLOGY

N-Glycans ofPhaeodactylum tricornutumDiatom and Functional Characterization of ItsN-Acetylglucosaminyltransferase I Enzyme

(2010) Bérengère Baïet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Production of antibodies in plants: status after twenty years

(2010) Benoit De Muynck et al.   PLANT BIOTECHNOLOGY JOURNAL

An Outlook on Microalgal Biofuels

(2010) R. H. Wijffels et al.   SCIENCE

Therapeutic antibodies: successes, limitations and hopes for the future

(2009) Patrick Chames et al.   BRITISH JOURNAL OF PHARMACOLOGY

Plant-made vaccine antigens and biopharmaceuticals

(2009) Henry Daniell et al.   TRENDS IN PLANT SCIENCE

Production systems for recombinant antibodies

(2008) Thomas Schirrmann   Frontiers in Bioscience-Landmark