Assessment of Heparanase-Mediated Angiogenesis Using Microvascular Endothelial Cells: Identification of λ-Carrageenan Derivative as a Potent Anti Angiogenic Agent

Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease

(2017) Ton J. Rabelink et al.   Nature Reviews Nephrology

Anti-heparanase activity of ultra-low-molecular-weight heparin produced by physicochemical depolymerization

(2016) Oussama Achour et al.   CARBOHYDRATE POLYMERS

Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases

(2016) Silvia Rivara et al.   Future Medicinal Chemistry

Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase

(2016) Daniele Pala et al.   GLYCOBIOLOGY

The US regulatory and pharmacopeia response to the global heparin contamination crisis

(2016) Anita Y Szajek et al.   NATURE BIOTECHNOLOGY

Modulation of the binding of basic fibroblast growth factor and heparanase activity by purified λ-carrageenan oligosaccharides

(2015) Ting-Ting Niu et al.   CARBOHYDRATE POLYMERS

Structural characterization of human heparanase reveals insights into substrate recognition

(2015) Liang Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural characterization of human heparanase reveals insights into substrate recognition

(2015) Liang Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The potential of heparanase as a therapeutic target in cancer

(2014) Claudio Pisano et al.   BIOCHEMICAL PHARMACOLOGY

Ultrasonic-assisted preparation of a low molecular weight heparin (LMWH) with anticoagulant activity

(2013) Oussama Achour et al.   CARBOHYDRATE POLYMERS

Hypoxia-Regulated Overexpression of Soluble VEGFR2 Controls Angiogenesis and Inhibits Tumor Growth

(2013) G. Collet et al.   MOLECULAR CANCER THERAPEUTICS

Synthetic heparin

(2012) Robert J Linhardt et al.   CURRENT OPINION IN PHARMACOLOGY

SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis

(2011) Joseph P. Ritchie et al.   CLINICAL CANCER RESEARCH

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae

(2011) Guangling Jiao et al.   Marine Drugs

Nitric oxide modulates the expression of endothelial cell adhesion molecules involved in angiogenesis and leukocyte recruitment

(2010) Aude Carreau et al.   EXPERIMENTAL CELL RESEARCH

Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis

(2010) Uri Barash et al.   FEBS Journal

Unraveling the Specificity of Heparanase Utilizing Synthetic Substrates

(2010) Sherket B. Peterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of tumor microvascular structure and permeability: comparison between magnetic resonance imaging and intravital confocal imaging

(2010) Nina Kristine Reitan et al.   JOURNAL OF BIOMEDICAL OPTICS

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy

(2009) K. Dredge et al.   INVESTIGATIONAL NEW DRUGS

Heparanase: busy at the cell surface

(2009) Liat Fux et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heparanase: One Molecule with Multiple Functions in Cancer Progression

(2008) Israel Vlodavsky et al.   CONNECTIVE TISSUE RESEARCH

PI-88: a novel inhibitor of angiogenesis

(2008) Ragini Kudchadkar et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment

(2008) Ghada Abboud-Jarrous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY