Amyloid β-Derived Diffusible Ligands (ADDLs) Induce Abnormal Autophagy Associated with Aβ Aggregation Degree

Administration of Amyloid-β42 Oligomer-Specific Monoclonal Antibody Improved Memory Performance in SAMP8 Mice

(2018) Ying Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Probing and Trapping a Sensitive Conformation: Amyloid-β Fibrils, Oligomers, and Dimers

(2018) Janelle N. Fawver et al.   JOURNAL OF ALZHEIMERS DISEASE

Parkin Null Cortical Neuronal/Glial Cultures are Resistant to Amyloid-β1-42 Toxicity: A Role for Autophagy?

(2018) Rosa M. Solano et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-β Secretion, Generation, and Lysosomal Sequestration in Response to Proteasome Inhibition: Involvement of Autophagy

(2018) Lotta Agholme et al.   JOURNAL OF ALZHEIMERS DISEASE

Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer’s disease neurons

(2017) Prasad Tammineni et al.   eLife

p62 improves AD-like pathology by increasing autophagy

(2016) A Caccamo et al.   MOLECULAR PSYCHIATRY

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

(2014) Michela Guglielmotto et al.   Autophagy

FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice

(2013) Takehiro Nakagaki et al.   Autophagy

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons

(2013) Karen Castillo et al.   Autophagy

Latrepirdine (Dimebon®), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model

(2013) John W. Steele et al.   Autophagy

Calix[6]arene bypasses human pancreatic cancer aggressiveness: Downregulation of receptor tyrosine kinases and induction of cell death by reticulum stress and autophagy

(2013) Karin Juliane Pelizzaro-Rocha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Methionine Inhibits Autophagy and Promotes Growth by Inducing the SAM-Responsive Methylation of PP2A

(2013) Benjamin M. Sutter et al.   CELL

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Autophagy Modulation for Alzheimer’s Disease Therapy

(2013) Xi-Chen Zhu et al.   MOLECULAR NEUROBIOLOGY

Amyloid β Peptides Promote Autophagy-Dependent Differentiation of Mouse Neural Stem Cells

(2013) Maria B. Fonseca et al.   MOLECULAR NEUROBIOLOGY

Vibrio effector protein, VopQ, forms a lysosomal gated channel that disrupts host ion homeostasis and autophagic flux

(2013) A. Sreelatha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

(2013) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Development of a Sensitive Phospho-p70 S6 Kinase ELISA to Quantify mTOR Proliferation Signal Inhibition

(2013) Bertram Hartmann et al.   THERAPEUTIC DRUG MONITORING

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo

(2012) Erin E. Congdon et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease

(2012) Aaron Y. Lai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Crosstalk between the ubiquitin–proteasome system and autophagy in a human cellular model of Alzheimer's disease

(2012) Valentina Cecarini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy impairment: a crossroad between neurodegeneration and tauopathies

(2012) Melissa Nassif et al.   BMC BIOLOGY

Role of mitochondrial homeostasis and dynamics in Alzheimer's disease

(2012) J. Eva Selfridge et al.   NEUROBIOLOGY OF DISEASE

Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells

(2011) Lin Zheng et al.   Autophagy

Presenilin Is Necessary for Efficient Proteolysis through the Autophagy-Lysosome System in a  -Secretase-Independent Manner

(2011) K. M. Neely et al.   JOURNAL OF NEUROSCIENCE

Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics

(2011) Cong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling

(2011) Sung Min Son et al.   NEUROBIOLOGY OF AGING

Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons—Dissociation from Cholesterol Homeostasis

(2011) Jürgen Zschocke et al.   NEUROPSYCHOPHARMACOLOGY

Novel demonstration of amyloid-β oligomers in sporadic inclusion-body myositis muscle fibers

(2010) Anna Nogalska et al.   ACTA NEUROPATHOLOGICA

Autophagy and misfolded proteins in neurodegeneration

(2010) Daniel J. Metcalf et al.   EXPERIMENTAL NEUROLOGY

ADDLs and the signaling web that leads to Alzheimer’s disease

(2010) Grant A. Krafft et al.   NEUROPHARMACOLOGY

Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

(2010) Belen Tizon et al.   PLoS One

Autophagy, a guardian against neurodegeneration

(2010) Moisés García-Arencibia et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Autophagy protects neuron from Aβ-induced cytotoxicity

(2009) Shih-Ya Hung et al.   Autophagy

Using LC3 to monitor autophagy flux in the retinal pigment epithelium

(2009) Ai Ling Wang et al.   Autophagy

In vitro reconstitution of fusion between immature autophagosomes and endosomes

(2009) Joëlle Morvan et al.   Autophagy

Vaccination with soluble Aβ oligomers generates toxicity-neutralizing antibodies

(2003) Mary P. Lambert et al.   JOURNAL OF NEUROCHEMISTRY