Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis inPseudomonasSepsis

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

(2016) Sivapriya Kailasan Vanaja et al.   CELL

The intersection of cell death and inflammasome activation

(2016) James E. Vince et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

(2016) Rajendra Karki et al.   NATURE

NOD-Like Receptors in Infection, Immunity, and Diseases

(2016) Young Keun Kim et al.   YONSEI MEDICAL JOURNAL

Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α

(2016) F Ren et al.   Cell Death & Disease

ER stress inducer tunicamycin suppresses the self-renewal of glioma-initiating cell partly through inhibiting Sox2 translation

(2016) Yang Xing et al.   Oncotarget

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice

(2016) Sisi He et al.   PLoS Pathogens

Atg7 Knockdown Augments Concanavalin A-Induced Acute Hepatitis through an ROS-Mediated p38/MAPK Pathway

(2016) Yan Zhuang et al.   PLoS One

Mitochondrial damage contributes toPseudomonas aeruginosaactivation of the inflammasome and is downregulated by autophagy

(2015) Majid Sakhi Jabir et al.   Autophagy

Pseudomonas aeruginosa Triggers Macrophage Autophagy To Escape Intracellular Killing by Activation of the NLRP3 Inflammasome

(2015) Qiuchan Deng et al.   INFECTION AND IMMUNITY

Annexin A2 Regulates Autophagy inPseudomonas aeruginosaInfection through the Akt1–mTOR–ULK1/2 Signaling Pathway

(2015) Rongpeng Li et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes of the intestinal epithelium

(2015) Mikael E. Sellin et al.   TRENDS IN IMMUNOLOGY

Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice

(2014) Yan Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pseudomonas aeruginosaType-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome

(2014) Emmanuel Faure et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A role for Nod-like receptors in autophagy induced byShigellainfection

(2014) Toshihiko Suzuki et al.   Autophagy

FIP200 is Involved in Murine Pseudomonas Infection by Regulating HMGB1 Intracellular Translocation

(2014) Yi Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during Pseudomonas aeruginosa Infection

(2014) S. Kannan et al.   JOURNAL OF IMMUNOLOGY

Atg7 Enhances Host Defense against Infection via Downregulation of Superoxide but Upregulation of Nitric Oxide

(2014) Xuefeng Li et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-302b augments host defense to bacteria by regulating inflammatory responses via feedback to TLR/IRAK4 circuits

(2014) Xikun Zhou et al.   Nature Communications

Lipid-Based Signaling Modulates DNA Repair Response and Survival againstKlebsiella pneumoniaeInfection in Host Cells and in Mice

(2013) Huang Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum

(2013) Serena Cervantes et al.   Autophagy

Proteome-wide Quantification and Characterization of Oxidation-Sensitive Cysteines in Pathogenic Bacteria

(2013) Xin Deng et al.   Cell Host & Microbe

Lyn regulates inflammatory responses inKlebsiella pneumoniaeinfection via the p38/NF-κB pathway

(2013) Xuefeng Li et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis

(2013) Nuno Figueiredo et al.   IMMUNITY

Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia

(2013) Taylor S. Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Lyn Mitigates Mouse Airway Remodeling by Downregulating the TGF- 3 Isoform in House Dust Mite Models

(2013) G. Li et al.   JOURNAL OF IMMUNOLOGY

Les inflammasomes

(2013) Yvan Jamilloux et al.   M S-MEDECINE SCIENCES

Autophagy Links Inflammasomes to Atherosclerotic Progression

(2012) Babak Razani et al.   Cell Metabolism

Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages

(2012) K. Yuan et al.   JOURNAL OF CELL SCIENCE

NLRC4 Inflammasome-Mediated Production of IL-1  Modulates Mucosal Immunity in the Lung against Gram-Negative Bacterial Infection

(2012) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity

(2012) Bénédicte F. Py et al.   MOLECULAR CELL

Elevated Inflammatory Response in Caveolin-1-deficient Mice withPseudomonas aeruginosaInfection Is Mediated by STAT3 Protein and Nuclear Factor κB (NF-κB)

(2011) Kefei Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens

(2011) Heike D. Lenz et al.   PLANT JOURNAL

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes

(2010) Shubham Shrivastava et al.   HEPATOLOGY

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Broad DNA repair responses in neural injury are associated with activation of the IL-6 pathway in cholesterol-fed rabbits

(2009) Min Wu et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

(2009) K. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy and the Immune Response to TB

(2009) J. Harris et al.   Transboundary and Emerging Diseases

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Pseudomonas aeruginosa activates caspase 1 through Ipaf

(2008) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA