IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity

Adipose tissue macrophages: going off track during obesity

(2016) Lily Boutens et al.   DIABETOLOGIA

Osteopontin affects macrophage polarization promoting endocytic but not inflammatory properties

(2016) Karina Schuch et al.   Obesity

Local proliferation initiates macrophage accumulation in adipose tissue during obesity

(2016) C Zheng et al.   Cell Death & Disease

Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity

(2016) Matteo Tardelli et al.   Molecular Metabolism

A method for long-term live imaging of tissue macrophages in adipose tissue explants

(2015) Martin Gericke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1

(2015) Yulia Haim et al.   Autophagy

Interleukin-6 gene transfer reverses body weight gain and fatty liver in obese mice

(2015) Yongjie Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Granulocyte–macrophage colony-stimulating factor primes interleukin-13 production by macrophages via protease-activated receptor-2

(2015) Manabu Aoki et al.   BLOOD CELLS MOLECULES AND DISEASES

Mechanism of interleukin-13 production by granulocyte-macrophage colony-stimulating factor-dependent macrophages via protease-activated receptor-2

(2015) Rui Yamaguchi et al.   BLOOD CELLS MOLECULES AND DISEASES

Reprogramming of Monocytes by GM-CSF Contributes to Regulatory Immune Functions during Intestinal Inflammation

(2015) Jan Däbritz et al.   JOURNAL OF IMMUNOLOGY

CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages

(2015) Chunxing Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation

(2014) Shinya U. Amano et al.   Cell Metabolism

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Granzyme B Promotes Cytotoxic Lymphocyte Transmigration via Basement Membrane Remodeling

(2014) Monica D. Prakash et al.   IMMUNITY

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation

(2013) Julia Haase et al.   DIABETOLOGIA

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

(2013) Stephen J. Jenkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice

(2013) M. Aouadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action

(2010) F. Thomas Wunderlich et al.   Cell Metabolism

Receptors for NPY and PACAP differ in expression and activity during adipogenesis in the murine 3T3-L1 fibroblast cell line

(2009) Martin T Gericke et al.   BRITISH JOURNAL OF PHARMACOLOGY

Human IL6 enhances leptin action in mice

(2009) M. Sadagurski et al.   DIABETOLOGIA

WHO recognition of the global obesity epidemic

(2009) W P T James   INTERNATIONAL JOURNAL OF OBESITY

MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional Macrophages

(2009) A. Aziz et al.   SCIENCE

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

(2008) V. Bourlier et al.   CIRCULATION

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES

Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice

(2008) I. Murano et al.   JOURNAL OF LIPID RESEARCH