标题
Adipose tissue macrophages: going off track during obesity
作者
关键词
Adipose tissue, Fat, Immune cells, Inflammation, Insulin resistance, Macrophages, Metabolism, Obesity, Review
出版物
DIABETOLOGIA
Volume 59, Issue 5, Pages 879-894
出版商
Springer Nature
发表日期
2016-03-03
DOI
10.1007/s00125-016-3904-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A method for long-term live imaging of tissue macrophages in adipose tissue explants
- (2015) Martin Gericke et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation
- (2015) Xiaoyan Hui et al. Cell Metabolism
- Non-traditional cytokines: How catecholamines and adipokines influence macrophages in immunity, metabolism and the central nervous system
- (2015) Mark A. Barnes et al. CYTOKINE
- Fatty acids from fat cell lipolysis do not activate an inflammatory response but are stored as triacylglycerols in adipose tissue macrophages
- (2015) Sylvie Caspar-Bauguil et al. DIABETOLOGIA
- Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages
- (2015) Ryan G. Snodgrass et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK)
- (2015) Kenny L. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Macrophage recruitment in obese adipose tissue
- (2015) Y. Bai et al. Obesity Reviews
- Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment
- (2015) Andrea A. Hill et al. Molecular Metabolism
- A major role of insulin in promoting obesity-associated adipose tissue inflammation
- (2015) David J. Pedersen et al. Molecular Metabolism
- Chronic Inhibition of PDE5 Limits Pro-Inflammatory Monocyte-Macrophage Polarization in Streptozotocin-Induced Diabetic Mice
- (2015) Mary Anna Venneri et al. PLoS One
- Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes
- (2014) Dan Gao et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages
- (2014) Yasutaka Okabe et al. CELL
- Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat
- (2014) Yifu Qiu et al. CELL
- Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis
- (2014) Rajesh R. Rao et al. CELL
- Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity
- (2014) Yun Sok Lee et al. CELL
- Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity
- (2014) Prabhakara R. Nagareddy et al. Cell Metabolism
- Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages
- (2014) Mario Kratz et al. Cell Metabolism
- Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation
- (2014) Shinya U. Amano et al. Cell Metabolism
- Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
- (2014) Ingrid Wernstedt Asterholm et al. Cell Metabolism
- Macrophage HIF-2 Ameliorates Adipose Tissue Inflammation and Insulin Resistance in Obesity
- (2014) S. S. Choe et al. DIABETES
- Reducing RIP140 Expression in Macrophage Alters ATM Infiltration, Facilitates White Adipose Tissue Browning, and Prevents High-Fat Diet-Induced Insulin Resistance
- (2014) P.-S. Liu et al. DIABETES
- Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation
- (2014) Slava Epelman et al. IMMUNITY
- Understanding macrophage diversity at the ontogenic and transcriptomic levels
- (2014) Emmanuel L. Gautier et al. IMMUNOLOGICAL REVIEWS
- Responses of macrophages to the danger signals released from necrotic cells
- (2014) T. Kimura et al. INTERNATIONAL IMMUNOLOGY
- Alarmin high-mobility group B1 (HMGB1) is regulated in human adipocytes in insulin resistance and influences insulin secretion in β-cells
- (2014) R Guzmán-Ruiz et al. INTERNATIONAL JOURNAL OF OBESITY
- Peripheral Monocytes of Obese Women Display Increased Chemokine Receptor Expression and Migration Capacity
- (2014) P. Krinninger et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Thioredoxin-Interacting Protein Stimulates Its Own Expression via a Positive Feedback Loop
- (2014) Junqin Chen et al. MOLECULAR ENDOCRINOLOGY
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
- (2014) Bhama Ramkhelawon et al. NATURE MEDICINE
- Pro- and anti-inflammatory cytokine gene expression in subcutaneous and visceral fat in severe obesity
- (2014) B. Spoto et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Cultured 3T3L1 adipocytes dispose of excess medium glucose as lactate under abundant oxygen availability
- (2014) David Sabater et al. Scientific Reports
- Human Adipose Tissue Macrophages Are Enhanced but Changed to an Anti-Inflammatory Profile in Obesity
- (2014) Karen Fjeldborg et al. Journal of Immunology Research
- Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells
- (2014) Kanakadurga Singer et al. Molecular Metabolism
- Linoleic acid: Between doubts and certainties
- (2013) Benjamin Choque et al. BIOCHIMIE
- Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation
- (2013) Xiaoyuan Xu et al. Cell Metabolism
- Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration
- (2013) Yun-Hee Lee et al. Cell Metabolism
- Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity
- (2013) Manoj Kumar Gunasekaran et al. CYTOKINE
- The developmental origins of adipose tissue
- (2013) Daniel C. Berry et al. DEVELOPMENT
- Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice
- (2013) S. Fujisaka et al. DIABETOLOGIA
- Start of insulin therapy in patients with type 2 diabetes mellitus promotes the influx of macrophages into subcutaneous adipose tissue
- (2013) H. J. Jansen et al. DIABETOLOGIA
- Adipose Tissue Foam Cells Are Present in Human Obesity
- (2013) Hagit Shapiro et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Insulin Inhibits IL-10-Mediated Regulatory T Cell Function: Implications for Obesity
- (2013) J. M. Han et al. JOURNAL OF IMMUNOLOGY
- Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis
- (2013) Antonio Giordano et al. JOURNAL OF LIPID RESEARCH
- Adipocyte triglyceride turnover and lipolysis in lean and overweight subjects
- (2013) Mikael Rydén et al. JOURNAL OF LIPID RESEARCH
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Tissue-resident macrophages
- (2013) Luke C Davies et al. NATURE IMMUNOLOGY
- Hypoxia and Adipose Tissue Function and Dysfunction in Obesity
- (2013) Paul Trayhurn PHYSIOLOGICAL REVIEWS
- B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile
- (2013) J. DeFuria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chronic adipose tissue inflammation: all immune cells on the stage
- (2013) Gökhan Cildir et al. TRENDS IN MOLECULAR MEDICINE
- Mechanisms of Inflammatory Responses in Obese Adipose Tissue
- (2012) Shengyi Sun et al. Annual Review of Nutrition
- Stearic Acid Accumulation in Macrophages Induces Toll-Like Receptor 4/2-Independent Inflammation Leading to Endoplasmic Reticulum Stress–Mediated Apoptosis
- (2012) Emily K. Anderson et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- In situ production of innate immune cells in murine white adipose tissue
- (2012) S. Poglio et al. BLOOD
- CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status
- (2012) H. Kitade et al. DIABETES
- Dendritic Cells Promote Macrophage Infiltration and Comprise a Substantial Proportion of Obesity-Associated Increases in CD11c+ Cells in Adipose Tissue and Liver
- (2012) M. Stefanovic-Racic et al. DIABETES
- Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity
- (2012) E. Arner et al. DIABETES
- Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production
- (2012) Lydia Lynch et al. IMMUNITY
- Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
- (2012) Saswata Talukdar et al. NATURE MEDICINE
- Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
- (2012) Durba Pal et al. NATURE MEDICINE
- The cellular and signaling networks linking the immune system and metabolism in disease
- (2012) Olivia Osborn et al. NATURE MEDICINE
- Relation of depot-specific adipose inflammation to insulin resistance in human obesity
- (2012) S J Bigornia et al. Nutrition & Diabetes
- Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes
- (2011) A. Krings et al. BONE
- Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation
- (2011) Gijs H. Goossens et al. CIRCULATION
- Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance
- (2011) Y. S. Lee et al. DIABETES
- Increased Macrophage Migration Into Adipose Tissue in Obese Mice
- (2011) D. Y. Oh et al. DIABETES
- Diabetes Adversely Affects Macrophages During Atherosclerotic Plaque Regression in Mice
- (2011) S. Parathath et al. DIABETES
- High-Fat Diet-Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation
- (2011) D. Feng et al. DIABETES
- Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells
- (2011) R. W. O’Rourke et al. DIABETOLOGIA
- The Inflammasome and Caspase-1 Activation: A New Mechanism Underlying Increased Inflammatory Activity in Human Visceral Adipose Tissue
- (2011) Tim B. Koenen et al. ENDOCRINOLOGY
- Targeted Deletion of Adipocytes by Apoptosis Leads to Adipose Tissue Recruitment of Alternatively Activated M2 Macrophages
- (2011) Pamela Fischer-Posovszky et al. ENDOCRINOLOGY
- Innate and adaptive immune responses to cell death
- (2011) Kenneth L. Rock et al. IMMUNOLOGICAL REVIEWS
- Adipose tissue macrophages inhibit adipogenesis of mesenchymal precursor cells via wnt-5a in humans
- (2011) R Bilkovski et al. INTERNATIONAL JOURNAL OF OBESITY
- Regulation of Lipolysis in Small and Large Fat Cells of the Same Subject
- (2011) Jurga Laurencikiene et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Dynamics of human adipose lipid turnover in health and metabolic disease
- (2011) Peter Arner et al. NATURE
- Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
- (2011) Khoa D. Nguyen et al. NATURE
- B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
- (2011) Daniel A Winer et al. NATURE MEDICINE
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Modulation of Macrophage Efferocytosis in Inflammation
- (2011) Darlynn Korns et al. Frontiers in Immunology
- Saturated Fatty Acids and Inflammation: Who Pays the Toll?
- (2010) Alan Chait et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity
- (2010) Rinke Stienstra et al. Cell Metabolism
- The Impact of Macrophage Insulin Resistance on Advanced Atherosclerotic Plaque Progression
- (2010) Ira Tabas et al. CIRCULATION RESEARCH
- Activin A Plays a Critical Role in Proliferation and Differentiation of Human Adipose Progenitors
- (2010) L.-E. Zaragosi et al. DIABETES
- Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
- (2010) J. M. Wentworth et al. DIABETES
- Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss
- (2010) A. Divoux et al. DIABETES
- Differential activation and antagonistic function of HIF- isoforms in macrophages are essential for NO homeostasis
- (2010) N. Takeda et al. GENES & DEVELOPMENT
- Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression
- (2010) M Zeyda et al. INTERNATIONAL JOURNAL OF OBESITY
- Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants
- (2010) J Ølholm et al. INTERNATIONAL JOURNAL OF OBESITY
- Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice
- (2010) Pingping Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
- (2010) Aliki Kosteli et al. JOURNAL OF CLINICAL INVESTIGATION
- Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance
- (2010) Jan Mauer et al. PLoS Genetics
- Differences in lipogenesis and lipolysis in obese and non-obese adult human adipocytes
- (2009) MARIANA CIFUENTES et al. BIOLOGICAL RESEARCH
- Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
- (2009) H.-Y. Fang et al. BLOOD
- Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-γ in inflammation in human adipose tissue
- (2009) R W O'Rourke et al. INTERNATIONAL JOURNAL OF OBESITY
- Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis
- (2009) Naim Alkhouri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Hypoxia-Inducible Factor 1 Induces Fibrosis and Insulin Resistance in White Adipose Tissue
- (2009) N. Halberg et al. MOLECULAR AND CELLULAR BIOLOGY
- Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
- (2009) Jian Liu et al. NATURE MEDICINE
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- (2009) Markus Feuerer et al. NATURE MEDICINE
- Normalization of obesity-associated insulin resistance through immunotherapy
- (2009) Shawn Winer et al. NATURE MEDICINE
- Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
- (2009) S. S. Iyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Inflammatory Response to Cell Death
- (2008) Kenneth L. Rock et al. Annual Review of Pathology-Mechanisms of Disease
- T-lymphocyte Infiltration in Visceral Adipose Tissue
- (2008) Ulrich Kintscher et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages
- (2008) V. Bourlier et al. CIRCULATION
- Adipose Tissue Macrophages, Low Grade Inflammation and Insulin Resistance in Human Obesity
- (2008) Leonie Heilbronn et al. CURRENT PHARMACEUTICAL DESIGN
- Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals
- (2008) G. Boden et al. DIABETES
- Reduced Adipose Tissue Oxygenation in Human Obesity: Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
- (2008) M. Pasarica et al. DIABETES
- Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
- (2008) C. N. Lumeng et al. DIABETES
- S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2
- (2008) Jin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evidence ofin SituProliferation of Adult Adipose Tissue-Derived Progenitor Cells: Influence of Fat Mass Microenvironment and Growth
- (2008) Marie Maumus et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
- (2008) I. Murano et al. JOURNAL OF LIPID RESEARCH
- The antiadipogenic effect of macrophage-conditioned medium depends on ERK1/2 activation
- (2008) Vanessa A. Constant et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Dynamics of fat cell turnover in humans
- (2008) Kirsty L. Spalding et al. NATURE
- Mechanisms of macrophage activation in obesity-induced insulin resistance
- (2008) Justin I Odegaard et al. Nature clinical practice. Endocrinology & metabolism
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started