Recent advances in vesicular stomatitis virus-based oncolytic virotherapy: a 5-year update

Oncolytic Maraba Virus MG1 as a Treatment for Sarcoma

(2017) Fabrice Le Boeuf et al.   INTERNATIONAL JOURNAL OF CANCER

Ruxolitinib and Polycation Combination Treatment Overcomes Multiple Mechanisms of Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus

(2017) Sébastien A. Felt et al.   JOURNAL OF VIROLOGY

Chikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain

(2017) Anthony N. van den Pol et al.   JOURNAL OF VIROLOGY

Inhibitory Receptors Induced by VSV Viroimmunotherapy Are Not Necessarily Targets for Improving Treatment Efficacy

(2017) Kevin G. Shim et al.   MOLECULAR THERAPY

Oncolytic VSV Primes Differential Responses to Immuno-oncology Therapy

(2017) Nicholas M. Durham et al.   MOLECULAR THERAPY

Oncolytic Virotherapy: A Contest between Apples and Oranges

(2017) Stephen J. Russell et al.   MOLECULAR THERAPY

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

(2017) David Olagnier et al.   MOLECULAR THERAPY

Curcumin promotes the oncoltyic capacity of vesicular stomatitis virus for the treatment of prostate cancers

(2017) Dylan J. Fehl et al.   VIRUS RESEARCH

NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine

(2017) Almohanad A. Alkayyal et al.   Cancer Immunology Research

Oncolytic Recombinant Vesicular Stomatitis Virus (VSV) Is Nonpathogenic and Nontransmissible in Pigs, a Natural Host of VSV

(2017) Lauro Velazquez-Salinas et al.   Human Gene Therapy Clinical Development

Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene Therapy

(2017) Christian Bressy et al.   Molecular Therapy-Oncolytics

Enhancing the Oncolytic Activity of CD133-Targeted Measles Virus: Receptor Extension or Chimerism with Vesicular Stomatitis Virus Are Most Effective

(2017) Dina Kleinlützum et al.   Frontiers in Oncology

Hepatitis C virus core protein enhances hepatocellular carcinoma cells to be susceptible to oncolytic vesicular stomatitis virus through down-regulation of HDAC4

(2016) Jeong Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A mathematical approach to virus therapy of glioblastomas

(2016) Victor Lopez de Rioja et al.   Biology Direct

Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy

(2016) E Ilett et al.   GENE THERAPY

Murine Tumor Models for Oncolytic Rhabdo-Virotherapy

(2016) Theresa Falls et al.   ILAR JOURNAL

Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses

(2016) Amber Miller et al.   MOLECULAR THERAPY

Robust Oncolytic Virotherapy Induces Tumor Lysis Syndrome and Associated Toxicities in the MPC-11 Plasmacytoma Model

(2016) Lianwen Zhang et al.   MOLECULAR THERAPY

A PTENtial cause for the selectivity of oncolytic viruses?

(2016) Brian R Champion et al.   NATURE IMMUNOLOGY

Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model

(2016) Christine C. Dobson et al.   Oncotarget

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

(2016) Eric Hastie et al.   Oncotarget

Constrained evolvability of interferon suppression in an RNA virus

(2016) Raquel Garijo et al.   Scientific Reports

Safety Studies in Tumor and Non-Tumor-Bearing Mice in Support of Clinical Trials Using Oncolytic VSV-IFNβ-NIS

(2016) Lianwen Zhang et al.   Human Gene Therapy Clinical Development

Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies

(2016) Laura Evgin et al.   Molecular Therapy-Oncolytics

N-Myc expression enhances the oncolytic effects of vesicular stomatitis virus in human neuroblastoma cells

(2016) Juan C Corredor et al.   Molecular Therapy-Oncolytics

Application of interferon modulators to overcome partial resistance of human ovarian cancers to VSV-GP oncolytic viral therapy

(2016) Catherine Dold et al.   Molecular Therapy-Oncolytics

Oncolytic vesicular stomatitis virus expressing interferon-σ has enhanced therapeutic activity

(2016) Marie-Claude Bourgeois-Daigneault et al.   Molecular Therapy-Oncolytics

Into the clinic: Talimogene laherparepvec (T-VEC), a first-in-class intratumoral oncolytic viral therapy

(2016) Hasan Rehman et al.   Journal for ImmunoTherapy of Cancer

Oncolytic Viruses: Therapeutics With an Identity Crisis

(2016) Caroline J. Breitbach et al.   EBioMedicine

Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia

(2015) W. Shen et al.   BLOOD

STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma

(2015) S Marozin et al.   CANCER GENE THERAPY

The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma

(2015) Kathleen M. Mahoney et al.   CLINICAL THERAPEUTICS

Livin modulates the apoptotic effects of vesicular stomatotitis virus in lung adenocarcinoma

(2015) GUI-HONG LIU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Definitive Management of Oligometastatic Melanoma in a Murine Model Using Combined Ablative Radiation Therapy and Viral Immunotherapy

(2015) Miran Blanchard et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Retargeting Oncolytic Vesicular Stomatitis Virus to Human T-Cell Lymphotropic Virus Type 1-Associated Adult T-Cell Leukemia

(2015) Dillon Betancourt et al.   JOURNAL OF VIROLOGY

Interferon Beta and Interferon Alpha 2a Differentially Protect Head and Neck Cancer Cells from Vesicular Stomatitis Virus-Induced Oncolysis

(2015) Marlena M. Westcott et al.   JOURNAL OF VIROLOGY

Changes in Susceptibility to Oncolytic Vesicular Stomatitis Virus during Progression of Prostate Cancer

(2015) Nanmeng Yu et al.   JOURNAL OF VIROLOGY

Lassa-Vesicular Stomatitis Chimeric Virus Safely Destroys Brain Tumors

(2015) Guido Wollmann et al.   JOURNAL OF VIROLOGY

Adapted ECHO-7 virus Rigvir immunotherapy (oncolytic virotherapy) prolongs survival in melanoma patients after surgical excision of the tumour in a retrospective study

(2015) Simona Doniņa et al.   MELANOMA RESEARCH

PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Model

(2015) Kim A Muñoz-Álvarez et al.   MOLECULAR THERAPY

Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling

(2015) Julia V. Cockle et al.   NEURO-ONCOLOGY

Vesicular stomatitis virus is a potent agent for the treatment of malignant ascites

(2015) YI ZHOU et al.   ONCOLOGY REPORTS

Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1

(2015) Marcela Cataldi et al.   VIROLOGY

Attenuation of vesicular stomatitis virus infection of brain using antiviral drugs and an adeno-associated virus-interferon vector

(2015) Guido Wollmann et al.   VIROLOGY

An unexpected inhibition of antiviral signaling by virus-encoded tumor suppressor p53 in pancreatic cancer cells

(2015) Eric Hastie et al.   VIROLOGY

Induction of apoptosis in pancreatic cancer cells by vesicular stomatitis virus

(2015) Sébastien A. Felt et al.   VIROLOGY

Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing

(2015) Rozanne Arulanandam et al.   Nature Communications

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

(2015) Manish R. Patel et al.   Oncotarget

Oncolytic potency of HER-2 retargeted VSV-FH hybrid viruses: the role of receptor ligand affinity

(2015) Camilo Ayala Breton et al.   Molecular Therapy-Oncolytics

Evidence for differential viral oncolytic efficacy in an in vitro model of epithelial ovarian cancer metastasis

(2015) Jessica G Tong et al.   Molecular Therapy-Oncolytics

Re-engineering Vesicular Stomatitis Virus to Abrogate Neurotoxicity, Circumvent Humoral Immunity, and Enhance Oncolytic Potency

(2014) A. Muik et al.   CANCER RESEARCH

Suppression of autophagic genes sensitizes CUG2-overexpressing A549 human lung cancer cells to oncolytic vesicular stomatitis virus-induced apoptosis

(2014) WARAPORN MALILAS et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Faster Replication and Higher Expression Levels of Viral Glycoproteins Give the Vesicular Stomatitis Virus/Measles Virus Hybrid VSV-FH a Growth Advantage over Measles Virus

(2014) C. Ayala-Breton et al.   JOURNAL OF VIROLOGY

Vesiculovirus Neutralization by Natural IgM and Complement

(2014) M. Z. Tesfay et al.   JOURNAL OF VIROLOGY

Type III Interferon Attenuates a Vesicular Stomatitis Virus-Based Vaccine Vector

(2014) R. C. Guayasamin et al.   JOURNAL OF VIROLOGY

Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy

(2014) Michelle Cronin et al.   MOLECULAR THERAPY

The Strength of the T Cell Response Against a Surrogate Tumor Antigen Induced by Oncolytic VSV Therapy Does Not Correlate With Tumor Control

(2014) Valérie Janelle et al.   MOLECULAR THERAPY

Maraba MG1 Virus Enhances Natural Killer Cell Function via Conventional Dendritic Cells to Reduce Postoperative Metastatic Disease

(2014) Jiqing Zhang et al.   MOLECULAR THERAPY

Oncogenic Ras inhibits IRF1 to promote viral oncolysis

(2014) Y Komatsu et al.   ONCOGENE

Experimental Evolution of an Oncolytic Vesicular Stomatitis Virus with Increased Selectivity for p53-Deficient Cells

(2014) Raquel Garijo et al.   PLoS One

Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back

(2014) Hesham Abdelbary et al.   TheScientificWorldJOURNAL

MUC1: a multifaceted oncoprotein with a key role in cancer progression

(2014) Sritama Nath et al.   TRENDS IN MOLECULAR MEDICINE

Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

(2014) Darija Muharemagic et al.   Molecular Therapy-Nucleic Acids

Reporter gene imaging identifies intratumoral infection voids as a critical barrier to systemic oncolytic virus efficacy

(2014) Amber Miller et al.   Molecular Therapy-Oncolytics

Cancer upregulated gene 2, a novel oncogene, confers resistance to oncolytic vesicular stomatitis virus through STAT1-OASL2 signaling

(2013) W Malilas et al.   CANCER GENE THERAPY

Meningeal myeloma deposits adversely impact the therapeutic index of an oncolytic VSV

(2013) D N Yarde et al.   CANCER GENE THERAPY

Overcoming cancer cell resistance to VSV oncolysis with JAK1/2 inhibitors

(2013) D Escobar-Zarate et al.   CANCER GENE THERAPY

Myeloid-Derived Suppressor Cells as a Vehicle for Tumor-Specific Oncolytic Viral Therapy

(2013) S. Eisenstein et al.   CANCER RESEARCH

Oncolytic vesicular stomatitis virus and bortezomib are antagonistic against myeloma cells in vitro but have additive anti-myeloma activity in vivo

(2013) Danielle N. Yarde et al.   EXPERIMENTAL HEMATOLOGY

Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors

(2013) B-Y Hwang et al.   GENE THERAPY

Oncolytic measles and vesicular stomatitis virotherapy for endometrial cancer

(2013) Yu-Ping Liu et al.   GYNECOLOGIC ONCOLOGY

Preclinical safety and activity of recombinant VSV-IFN-β in an immunocompetent model of squamous cell carcinoma of the head and neck

(2013) Vittal V. S. Kurisetty et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation

(2013) WARAPORN MALILAS et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Molecular determinants of susceptibility to oncolytic vesicular stomatitis virus in pancreatic adenocarcinoma

(2013) Aaron U. Blackham et al.   JOURNAL OF SURGICAL RESEARCH

PEGylation of Vesicular Stomatitis Virus Extends Virus Persistence in Blood Circulation of Passively Immunized Mice

(2013) M. Z. Tesfay et al.   JOURNAL OF VIROLOGY

Characteristics of Oncolytic Vesicular Stomatitis Virus Displaying Tumor-Targeting Ligands

(2013) A. Ammayappan et al.   JOURNAL OF VIROLOGY

Neuroattenuation of Vesicular Stomatitis Virus through Picornaviral Internal Ribosome Entry Sites

(2013) A. Ammayappan et al.   JOURNAL OF VIROLOGY

Vesicular Stomatitis Virus Variants Selectively Infect and Kill Human Melanomas but Not Normal Melanocytes

(2013) G. Wollmann et al.   JOURNAL OF VIROLOGY

Histone Deacetylase Inhibitors Potentiate Vesicular Stomatitis Virus Oncolysis in Prostate Cancer Cells by Modulating NF- B-Dependent Autophagy

(2013) L. Shulak et al.   JOURNAL OF VIROLOGY

Oncolytic Vesicular Stomatitis Virus in an Immunocompetent Model of MUC1-Positive or MUC1-Null Pancreatic Ductal Adenocarcinoma

(2013) E. Hastie et al.   JOURNAL OF VIROLOGY

Ablation of Nectin4 Binding Compromises CD46 Usage by a Hybrid Vesicular Stomatitis Virus/Measles Virus

(2013) Y.-P. Liu et al.   JOURNAL OF VIROLOGY

Antifibrotic Properties of Transarterial Oncolytic VSV Therapy for Hepatocellular Carcinoma in Rats With Thioacetamide-Induced Liver Fibrosis

(2013) Jennifer Altomonte et al.   MOLECULAR THERAPY

Triptolide-Mediated Inhibition of Interferon Signaling Enhances Vesicular Stomatitis Virus-Based Oncolysis

(2013) Fethia Ben Yebdri et al.   MOLECULAR THERAPY

Amalgamating Oncolytic Viruses to Enhance Their Safety, Consolidate Their Killing Mechanisms, and Accelerate Their Spread

(2013) Camilo Ayala-Breton et al.   MOLECULAR THERAPY

Suppression of Antiviral Innate Immunity by Sunitinib Enhances Oncolytic Virotherapy

(2013) Babal K Jha et al.   MOLECULAR THERAPY

BCL-2 Inhibitors Sensitize Therapy-resistant Chronic Lymphocytic Leukemia Cells to VSV Oncolysis

(2013) Sara Samuel et al.   MOLECULAR THERAPY

Maraba Virus as a Potent Oncolytic Vaccine Vector

(2013) Jonathan G Pol et al.   MOLECULAR THERAPY

Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics

(2013) Lisa F Gamwell et al.   Orphanet Journal of Rare Diseases

Oncolytic vesicular stomatitis virus as a treatment for neuroendocrine tumors

(2013) Reese W. Randle et al.   SURGERY

Understanding and altering cell tropism of vesicular stomatitis virus

(2013) Eric Hastie et al.   VIRUS RESEARCH

Model-based rational design of an oncolytic virus with improved therapeutic potential

(2013) Fabrice Le Bœuf et al.   Nature Communications

Non-replicating rhabdovirus-derived particles (NRRPs) eradicate acute leukemia by direct cytolysis and induction of antitumor immunity

(2013) C Batenchuk et al.   Blood Cancer Journal

Retargeting Vesicular Stomatitis Virus Glycoprotein Pseudotyped Lentiviral Vectors with Enhanced Stability by In Situ Synthesized Polymer Shell

(2013) Min Liang et al.   Human Gene Therapy Methods

Safety Studies on Intravenous Administration of Oncolytic Recombinant Vesicular Stomatitis Virus in Purpose-Bred Beagle Dogs

(2013) Amy K. LeBlanc et al.   Human Gene Therapy Clinical Development

Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8+T-cell responses to anticancer vaccines

(2013) Byram W Bridle et al.   OncoImmunology

Enhanced vesicular stomatitis virus (VSVΔ51) targeting of head and neck cancer in combination with radiation therapy or ZD6126 vascular disrupting agent

(2012) Nehad M Alajez et al.   Cancer Cell International

Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β

(2012) S Naik et al.   CANCER GENE THERAPY

Systemic Combination Virotherapy for Melanoma with Tumor Antigen-Expressing Vesicular Stomatitis Virus and Adoptive T-cell Transfer

(2012) D. M. Rommelfanger et al.   CANCER RESEARCH

The potential of recombinant vesicular stomatitis virus-mediated virotherapy against metastatic colon cancer

(2012) MINORU YAMAKI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer

(2012) E. Hastie et al.   JOURNAL OF GENERAL VIROLOGY

Inhibition of Type I Interferon-Mediated Antiviral Action in Human Glioma Cells by the IKK Inhibitors BMS-345541 and TPCA-1

(2012) Ziyun Du et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Semireplication-competent vesicular stomatitis virus as a novel platform for oncolytic virotherapy

(2012) Alexander Muik et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Anti-Fab Aptamers for Shielding Virus from Neutralizing Antibodies

(2012) Darija Muharemagic et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Vesicular Stomatitis Virus as an Oncolytic Agent against Pancreatic Ductal Adenocarcinoma

(2012) A. M. Murphy et al.   JOURNAL OF VIROLOGY

Highly Attenuated Recombinant Vesicular Stomatitis Virus VSV-12'GFP Displays Immunogenic and Oncolytic Activity

(2012) A. N. van den Pol et al.   JOURNAL OF VIROLOGY

Curative one-shot systemic virotherapy in murine myeloma

(2012) S Naik et al.   LEUKEMIA

The Efficacy Versus Toxicity Profile of Combination Virotherapy and TLR Immunotherapy Highlights the Danger of Administering TLR Agonists to Oncolytic Virus-treated Mice

(2012) Diana M Rommelfanger et al.   MOLECULAR THERAPY

Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma

(2012) Jose Pulido et al.   NATURE BIOTECHNOLOGY

Acute Reactogenicity after Intramuscular Immunization with Recombinant Vesicular Stomatitis Virus Is Linked to Production of IL-1β

(2012) Kathleen Athearn et al.   PLoS One

Variation in susceptibility of human malignant melanomas to oncolytic vesicular stomatitis virus

(2012) Aaron U. Blackham et al.   SURGERY

Resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus: Role of type I interferon signaling

(2012) Megan Moerdyk-Schauwecker et al.   VIROLOGY

Electrochemical Sensing of Aptamer-Facilitated Virus Immunoshielding

(2011) Mahmoud Labib et al.   ANALYTICAL CHEMISTRY

Dynamics of melanoma tumor therapy with vesicular stomatitis virus: explaining the variability in outcomes using mathematical modeling

(2011) D M Rommelfanger et al.   GENE THERAPY

Retargeting Vesicular Stomatitis Virus Using Measles Virus Envelope Glycoproteins

(2011) Camilo Ayala-Breton et al.   HUMAN GENE THERAPY

Sensitivity of cervical carcinoma cells to vesicular stomatitis virus-induced oncolysis: Potential role of human papilloma virus infection

(2011) Fabrice Le Boeuf et al.   INTERNATIONAL JOURNAL OF CANCER

Interferon: Current Status and Future Prospects in Cancer Therapy

(2011) Ben X. Wang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Vesicular Stomatitis Virus Expressing Tumor Suppressor p53 Is a Highly Attenuated, Potent Oncolytic Agent

(2011) J. F. Heiber et al.   JOURNAL OF VIROLOGY

Pseudotyping Vesicular Stomatitis Virus with Lymphocytic Choriomeningitis Virus Glycoproteins Enhances Infectivity for Glioma Cells and Minimizes Neurotropism

(2011) A. Muik et al.   JOURNAL OF VIROLOGY

Type III IFN Interleukin-28 Mediates the Antitumor Efficacy of Oncolytic Virus VSV in Immune-Competent Mouse Models of Cancer

(2010) Phonphimon Wongthida et al.   CANCER RESEARCH

Identification of Genetically Modified Maraba Virus as an Oncolytic Rhabdovirus

(2010) Jan Brun et al.   MOLECULAR THERAPY

Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing

(2010) Fabrice Le Boeuf et al.   MOLECULAR THERAPY

VSV Oncolysis in Combination With the BCL-2 Inhibitor Obatoclax Overcomes Apoptosis Resistance in Chronic Lymphocytic Leukemia

(2010) Sara Samuel et al.   MOLECULAR THERAPY

VSV virotherapy improves chemotherapy by triggering apoptosis due to proteasomal degradation of Mcl-1

(2009) P Schache et al.   GENE THERAPY

Safety Studies on Intrahepatic or Intratumoral Injection of Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Rodents and Nonhuman Primates

(2009) Nathan Jenks et al.   HUMAN GENE THERAPY

Some Attenuated Variants of Vesicular Stomatitis Virus Show Enhanced Oncolytic Activity against Human Glioblastoma Cells relative to Normal Brain Cells

(2009) G. Wollmann et al.   JOURNAL OF VIROLOGY

Synergistic antitumor effects of transarterial viroembolization for multifocal hepatocellular carcinoma in rats

(2008) Jennifer Altomonte et al.   HEPATOLOGY

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA