Predicting the targeting of tail-anchored proteins to subcellular compartments in mammalian cells

The VDAC2–BAK axis regulates peroxisomal membrane permeability

(2017) Ken-ichiro Hosoi et al.   JOURNAL OF CELL BIOLOGY

Development of a prediction system for tail-anchored proteins

(2016) Shunsuke Shigemitsu et al.   BMC BIOINFORMATICS

Tryptophan‐rich basic protein (WRB) mediates insertion of the tail‐anchored protein otoferlin and is required for hair cell exocytosis and hearing

(2016) Christian Vogl et al.   EMBO JOURNAL

ACBD5 deficiency causes a defect in peroxisomal very long-chain fatty acid metabolism

(2016) Sacha Ferdinandusse et al.   JOURNAL OF MEDICAL GENETICS

Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy

(2016) Johannes Koch et al.   JOURNAL OF MEDICAL GENETICS

Multiple selection filters ensure accurate tail-anchored membrane protein targeting

(2016) Meera Rao et al.   eLife

Peroxisome-mitochondria interplay and disease

(2015) Michael Schrader et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Structure of the Get3 targeting factor in complex with its membrane protein cargo

(2015) A. Mateja et al.   SCIENCE

Conserved targeting information in mammalian and fungal peroxisomal tail-anchored proteins

(2015) Judith Buentzel et al.   Scientific Reports

The Gdap1 knockout mouse mechanistically links redox control to Charcot–Marie–Tooth disease

(2014) Axel Niemann et al.   BRAIN

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins

(2014) Y.-C. Chen et al.   EMBO JOURNAL

Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy

(2014) Taras Y. Nazarko et al.   JOURNAL OF CELL BIOLOGY

The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins

(2014) V. Okreglak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bag6 complex contains a minimal tail-anchor–targeting module and a mock BAG domain

(2014) Jee-Young Mock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrophobic handoff for direct delivery of peroxisome tail-anchored proteins

(2014) Yinxiao Chen et al.   Nature Communications

A gatekeeper helix determines the substrate specificity of Sjögren–Larsson Syndrome enzyme fatty aldehyde dehydrogenase

(2014) Markus A. Keller et al.   Nature Communications

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission

(2013) Nina Huber et al.   EMBO REPORTS

Topogenesis and Homeostasis of Fatty Acyl-CoA Reductase 1

(2013) Masanori Honsho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathway

(2013) Yuichi Yagita et al.   JOURNAL OF CELL BIOLOGY

The Association of BAG6 with SGTA and Tail-Anchored Proteins

(2013) Pawel Leznicki et al.   PLoS One

Autozygome-guided exome sequencing in retinal dystrophy patients reveals pathogenetic mutations and novel candidate disease genes

(2012) L. Abu-Safieh et al.   GENOME RESEARCH

Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology

(2012) Kenta Onoue et al.   JOURNAL OF CELL SCIENCE

Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes

(2012) Hanan E Shamseldin et al.   JOURNAL OF MEDICAL GENETICS

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

(2012) Katrin Krumpe et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleosome Positioning: Multiple Mechanisms toward a Unifying Goal

(2012) Arnob Dutta et al.   MOLECULAR CELL

SGTA antagonizes BAG6-mediated protein triage

(2012) P. Leznicki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LIBSVM

(2012) Chih-Chung Chang et al.   ACM Transactions on Intelligent Systems and Technology

Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease

(2011) Marc Fransen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane

(2011) F. Vilardi et al.   JOURNAL OF CELL SCIENCE

R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals

(2011) Ian R. Kelsall et al.   JOURNAL OF NEUROCHEMISTRY

Protein targeting and degradation are coupled for elimination of mislocalized proteins

(2011) Tara Hessa et al.   NATURE

A mutation in PEX19 causes a severe clinical phenotype in a patient with peroxisomal biogenesis disorder

(2010) Sarar Mohamed et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Targeting pathways of C-tail-anchored proteins

(2010) Nica Borgese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic Reticulum

(2010) Fei Wang et al.   MOLECULAR CELL

A ribosome-associating factor chaperones tail-anchored membrane proteins

(2010) Malaiyalam Mariappan et al.   NATURE

Evolutionary origins of metabolic compartmentalization in eukaryotes

(2010) W. Martin   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Subcellular Distribution of Tail-Anchored Proteins in Arabidopsis

(2009) Verena Kriechbaumer et al.   TRAFFIC

The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane

(2008) Maya Schuldiner et al.   CELL

Targeting of hFis1 to Peroxisomes Is Mediated by Pex19p

(2008) Hannah K. Delille et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Precursor-specific Role for Hsp40/Hsc70 during Tail-anchored Protein Integration at the Endoplasmic Reticulum

(2008) Catherine Rabu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import components

(2008) C. Kemper et al.   JOURNAL OF CELL SCIENCE

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL