ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2–MRCKα balance

Myosin Light Chain Kinase (MLCK) Regulates Cell Migration in a Myosin Regulatory Light Chain Phosphorylation-independent Mechanism

(2014) Chen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer

(2014) Mathieu Unbekandt et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Talin and kindlin: the one-two punch in integrin activation

(2014) Feng Ye et al.   Frontiers of Medicine

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

CCM1–ICAP-1 complex controls β1 integrin–dependent endothelial contractility and fibronectin remodeling

(2013) Eva Faurobert et al.   JOURNAL OF CELL BIOLOGY

Monoubiquitination of Filamin B Regulates Vascular Endothelial Growth Factor-Mediated Trafficking of Histone Deacetylase 7

(2013) Y.-T. Su et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation

(2013) Weizhi Liu et al.   MOLECULAR CELL

Formin mDia1 senses and generates mechanical forces on actin filaments

(2013) Antoine Jégou et al.   Nature Communications

Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration

(2012) Antje Schaefer et al.   BIOCHEMICAL JOURNAL

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

(2012) Matthew Raab et al.   JOURNAL OF CELL BIOLOGY

The E3 Ubiquitin-Ligase HACE1 Catalyzes the Ubiquitylation of Active Rac1

(2011) Stéphanie Torrino et al.   DEVELOPMENTAL CELL

Pivotal Role of the C2 Domain of the Smurf1 Ubiquitin Ligase in Substrate Selection

(2011) Kefeng Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoblast mineralization requires β1 integrin/ICAP-1–dependent fibronectin deposition

(2011) Molly Brunner et al.   JOURNAL OF CELL BIOLOGY

A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels

(2011) Qingzong Tseng et al.   LAB ON A CHIP

Stretchy Proteins on Stretchy Substrates: The Important Elements of Integrin-Mediated Rigidity Sensing

(2010) Simon W. Moore et al.   DEVELOPMENTAL CELL

Non-canonical Wnt Signaling Induces Ubiquitination and Degradation of Syndecan4

(2010) Loreto Carvallo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles

(2009) C. Gally et al.   DEVELOPMENT

Cerebral Cavernous Malformation 2 Protein Promotes Smad Ubiquitin Regulatory Factor 1-mediated RhoA Degradation in Endothelial Cells

(2009) Lisa E. S. Crose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration

(2009) Cai Huang et al.   NATURE CELL BIOLOGY

Kindlin-2 controls bidirectional signaling of integrins

(2008) E. Montanez et al.   GENES & DEVELOPMENT

Cell adaptive response to extracellular matrix density is controlled by ICAP-1–dependent β1-integrin affinity

(2008) Angélique Millon-Frémillon et al.   JOURNAL OF CELL BIOLOGY

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

(2008) Kefeng Lu et al.   NATURE CELL BIOLOGY