Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

Tryptophan availability for kynurenine pathway metabolism across the life span: Control mechanisms and focus on aging, exercise, diet and nutritional supplements

(2017) Abdulla A-B. Badawy   NEUROPHARMACOLOGY

The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct

(2016) Serra Ucer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Central kynurenine pathway shift with age in women

(2016) Josien de Bie et al.   JOURNAL OF NEUROCHEMISTRY

Interactions between inflammatory mediators and corticosteroids regulate transcription of genes within the Kynurenine Pathway in the mouse hippocampus

(2016) Alexandra K. Brooks et al.   Journal of Neuroinflammation

The impact of low-protein high-carbohydrate diets on aging and lifespan

(2015) David G. Le Couteur et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Determinants of Muscle and Bone Aging

(2015) Elizabeth Curtis et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oxidation of the aromatic amino acids tryptophan and tyrosine disrupts their anabolic effects on bone marrow mesenchymal stem cells

(2015) Mona El Refaey et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

(2014) Leandro Z. Agudelo et al.   CELL

Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

(2014) Morgan E. Levine et al.   Cell Metabolism

Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study

(2014) E. M. Apalset et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

(2014) Richard Metz et al.   INTERNATIONAL IMMUNOLOGY

Kynurenines with Neuroactive and Redox Properties: Relevance to Aging and Brain Diseases

(2014) Jazmin Reyes Ocampo et al.   Oxidative Medicine and Cellular Longevity

The Kynurenine Pathway of Tryptophan Degradation is Activated During Osteoblastogenesis

(2014) Christopher Vidal et al.   STEM CELLS

Basic Biology of Skeletal Aging: Role of Stress Response Pathways

(2013) M. Almeida et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Mitochondrial metabolism of reactive oxygen species

(2013) Paola Venditti et al.   MITOCHONDRION

Tryptophan metabolism: entering the field of aging and age-related pathologies

(2013) Annemieke T. van der Goot et al.   TRENDS IN MOLECULAR MEDICINE

Histone deacetylase 3 is required for maintenance of bone mass during aging

(2012) Meghan E. McGee-Lawrence et al.   BONE

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes

(2012) Seithikurippu R. Pandi-Perumal et al.   NEUROTOXICITY RESEARCH

Sodium-dependent vitamin C transporter SVCT2: Expression and function in bone marrow stromal cells and in osteogenesis

(2012) Sadanand Fulzele et al.   Stem Cell Research

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats

(2011) Nady Braidy et al.   FEBS Journal

Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)

(2011) Juliana Croitoru-Lamoury et al.   PLoS One

Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells

(2011) Saara Marttila et al.   Immunity & Ageing

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis

(2009) Gabriel Criado et al.   ARTHRITIS AND RHEUMATISM

Mitochondrial function and redox control in the aging eye: Role of MsrA and other repair systems in cataract and macular degenerations

(2008) Lisa A. Brennan et al.   EXPERIMENTAL EYE RESEARCH

Age-Related Changes in the Osteogenic Differentiation Potential of Mouse Bone Marrow Stromal Cells

(2008) Weixi Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH