Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction

Neuropeptide VGF Promotes Maturation of Hippocampal Dendrites That Is Reduced by Single Nucleotide Polymorphisms

(2017) Joseph Behnke et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cerebellar granule cells encode the expectation of reward

(2017) Mark J. Wagner et al.   NATURE

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation

(2017) Stephani A. Davis et al.   NEUROBIOLOGY OF DISEASE

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease

(2017) Dasiel O. Borroto-Escuela et al.   Frontiers in Cellular Neuroscience

TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia

(2016) Bryan D. James et al.   BRAIN

Systemic inflammation induces anxiety disorder through CXCL12/CXCR4 pathway

(2016) L. Yang et al.   BRAIN BEHAVIOR AND IMMUNITY

A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway

(2016) Jung Min Song et al.   JOURNAL OF ALZHEIMERS DISEASE

TrkA mediates retrograde semaphorin 3A signaling through plexin A4 to regulate dendritic branching

(2016) Naoya Yamashita et al.   JOURNAL OF CELL SCIENCE

Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation

(2016) Stuart Maudsley et al.   METHODS

Age-related expression of Neurexin1 and Neuroligin3 is correlated with presynaptic density in the cerebral cortex and hippocampus of male mice

(2015) Dhiraj Kumar et al.   AGE

Homozygous SLC6A17 Mutations Cause Autosomal-Recessive Intellectual Disability with Progressive Tremor, Speech Impairment, and Behavioral Problems

(2015) Zafar Iqbal et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus

(2015) Phu V. Tran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Neural correlates of taste and pleasantness evaluation in the metabolic syndrome

(2015) Erin Green et al.   BRAIN RESEARCH

Mutations inSLC6A17cause autosomal-recessive intellectual disability

(2015) S. Waltl   CLINICAL GENETICS

Does Nutrient Sensing Determine How We “See” Food?

(2015) Sophie C. Hamr et al.   Current Diabetes Reports

Cerebral perfusion and glucose metabolism in Alzheimer’s disease and frontotemporal dementia: two sides of the same coin?

(2015) Sander C. J. Verfaillie et al.   EUROPEAN RADIOLOGY

L-Dopa improves learning and maintenance of new nouns in healthy adults

(2015) Copland David et al.   Frontiers in Human Neuroscience

Developmental expression of the neuroligins and neurexins in fragile X mice

(2015) Jonathan K.Y. Lai et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Aberrant Wnt signaling pathway in medial temporal lobe structures of Alzheimer’s disease

(2015) Jesper Riise et al.   JOURNAL OF NEURAL TRANSMISSION

The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex

(2015) D. Nie et al.   JOURNAL OF NEUROSCIENCE

Altered Sensory Experience Exacerbates Stable Dendritic Spine and Synapse Loss in a Mouse Model of Huntington's Disease

(2015) R. P. Murmu et al.   JOURNAL OF NEUROSCIENCE

Effects of Metabolic Syndrome on Language Functions in Aging

(2015) Dalia Cahana-Amitay et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

The metabolic syndrome in a memory clinic population: Relation with clinical profile and prognosis

(2015) Lieza G. Exalto et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

HINT1 is involved in the behavioral abnormalities induced by social isolation rearing

(2015) Yong-hui Dang et al.   NEUROSCIENCE LETTERS

Synaptic Therapy in Alzheimer’s Disease: A CREB-centric Approach

(2015) Andrew F. Teich et al.   Neurotherapeutics

GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses

(2015) Y Hotokezaka et al.   Cell Death & Disease

Ancient Transposable Elements Transformed the Uterine Regulatory Landscape and Transcriptome during the Evolution of Mammalian Pregnancy

(2015) Vincent J. Lynch et al.   Cell Reports

Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder

(2015) Caitlin M. Daimon et al.   Frontiers in Physiology

Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains

(2015) Jonathan Janssens et al.   Acta Neuropathologica Communications

A de novo 1.4-Mb deletion at 21q22.11 in a boy with developmental delay

(2014) Ryoko Fukai et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Autism-Related Neuroligin-3 Mutation Alters Social Behavior and Spatial Learning

(2014) Thomas C. Jaramillo et al.   Autism Research

Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease

(2014) Cassia R. Overk et al.   BIOCHEMICAL PHARMACOLOGY

Neuroprotective effects of PEP-1-carbonyl reductase 1 against oxidative-stress-induced ischemic neuronal cell damage

(2014) Young Nam Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Three-dimensional analysis of abnormal ultrastructural alteration in mitochondria of hippocampus of APP/PSEN1 transgenic mouse

(2014) Ki Ju Choi et al.   JOURNAL OF BIOSCIENCES

Tau-Mediated NMDA Receptor Impairment Underlies Dysfunction of a Selectively Vulnerable Network in a Mouse Model of Frontotemporal Dementia

(2014) Brian A. Warmus et al.   JOURNAL OF NEUROSCIENCE

Adipokine pathways are altered in hippocampus of an experimental mouse model of Alzheimer’s disease

(2014) I. Pedrós et al.   Journal of Nutrition Health & Aging

Sporadic Creutzfeldt–Jakob disease with mesiotemporal hypermetabolism

(2014) Philipp Euskirchen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease

(2014) Dai Yuki et al.   Scientific Reports

Quantifying the Eating Abnormalities in Frontotemporal Dementia

(2014) Rebekah M. Ahmed et al.   JAMA Neurology

Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients

(2014) Rui Wang et al.   Frontiers in Physiology

Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice

(2013) Nan Lin et al.   BEHAVIOURAL BRAIN RESEARCH

Taste receptors of the gut: emerging roles in health and disease

(2013) Inge Depoortere   GUT

Age-dependent role for Ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrus

(2013) Michael J. Darcy et al.   HIPPOCAMPUS

Low-Level Laser Therapy Rescues Dendrite Atrophy via Upregulating BDNF Expression: Implications for Alzheimer's Disease

(2013) C. Meng et al.   JOURNAL OF NEUROSCIENCE

Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex

(2013) G. A. Rodriguez et al.   LEARNING & MEMORY

Minireview: Nutrient Sensing by G Protein-Coupled Receptors

(2013) Eric M. Wauson et al.   MOLECULAR ENDOCRINOLOGY

Deregulation of calcium homeostasis mediates secreted α–synuclein-induced neurotoxicity

(2013) Katerina Melachroinou et al.   NEUROBIOLOGY OF AGING

Anterior brain glucose hypometabolism predates dementia in progranulin mutation carriers

(2013) C. Jacova et al.   NEUROLOGY

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment

(2013) Scott E. Counts et al.   NEUROPHARMACOLOGY

VennPlex–A Novel Venn Diagram Program for Comparing and Visualizing Datasets with Differentially Regulated Datapoints

(2013) Huan Cai et al.   PLoS One

Textrous!: Extracting Semantic Textual Meaning from Gene Sets

(2013) Hongyu Chen et al.   PLoS One

Long-Term Artificial Sweetener Acesulfame Potassium Treatment Alters Neurometabolic Functions in C57BL/6J Mice

(2013) Wei-na Cong et al.   PLoS One

Olfactory Deficits in Frontotemporal Dementia as Measured by the Alberta Smell Test

(2013) Daniel J. Heyanka et al.   Applied Neuropsychology-Adult

Effective use of latent semantic indexing and computational linguistics in biological and biomedical applications

(2013) Hongyu Chen et al.   Frontiers in Physiology

O-GlcNAc modification affects the ATM-mediated DNA damage response

(2012) Yuri Miura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Anticonvulsant activity of artificial sweeteners: A structural link between sweet-taste receptor T1R3 and brain glutamate receptors

(2012) Alan Talevi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Frontotemporal Lobar Degeneration

(2012) Rachel E. Seltman et al.   CNS DRUGS

Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders

(2012) Luigi Boccuto et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Epinephrine and glucose modulate training-related CREB phosphorylation in old rats: Relationships to age-related memory impairments

(2012) Ken A. Morris et al.   EXPERIMENTAL GERONTOLOGY

Euglycemic Agent-mediated Hypothalamic Transcriptomic Manipulation in the N171–82Q Model of Huntington Disease Is Related to Their Physiological Efficacy

(2012) Bronwen Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo neurochemical imaging of olfactory dysfunction in Parkinson’s disease

(2012) Nicolaas I. Bohnen et al.   JOURNAL OF NEURAL TRANSMISSION

Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNA repair gene XPA

(2012) Gregor Tomasevic et al.   JOURNAL OF NEUROSURGERY

Discovery- and target-based protein quantification using iTRAQ and pulsed Q collision induced dissociation (PQD)

(2012) Wells W. Wu et al.   Journal of Proteomics

The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and Autophagy

(2012) Eric M. Wauson et al.   MOLECULAR CELL

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Cognitive impairment in major depression and the mGlu2 receptor as a therapeutic target

(2012) Celia Goeldner et al.   NEUROPHARMACOLOGY

Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease

(2012) Wei-na Cong et al.   PLoS One

Studying Signal Transduction in Single Dendritic Spines

(2012) R. Yasuda   Cold Spring Harbor Perspectives in Biology

T1R3: A human calcium taste receptor

(2012) Michael G. Tordoff et al.   Scientific Reports

Inferring novel gene-disease associations using Medical Subject Heading Over-representation Profiles

(2012) Warren A Cheung et al.   Genome Medicine

Group 1 Metabotropic Glutamate Receptor Function and Its Regulation of Learning and Memory in the Aging Brain

(2012) Caroline Ménard et al.   Frontiers in Pharmacology

Functional morphological imaging of autism spectrum disorders: Current position and theories proposed

(2012) M.-A. Lauvin et al.   Diagnostic and Interventional Imaging

Taste receptor signalling - from tongues to lungs

(2011) S. C. Kinnamon   Acta Physiologica

Increased anxiety-related behaviour in Hint1 knockout mice

(2011) Jeeva Varadarajulu et al.   BEHAVIOURAL BRAIN RESEARCH

Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus

(2011) Oliver von Bohlen und Halbach   CELL AND TISSUE RESEARCH

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

(2011) P Richards et al.   CELL DEATH AND DIFFERENTIATION

PSD-95-like membrane associated guanylate kinases (PSD-MAGUKs) and synaptic plasticity

(2011) Weifeng Xu   CURRENT OPINION IN NEUROBIOLOGY

Peptidyl-prolyl cis–trans isomerase Pin1 in ageing, cancer and Alzheimer disease

(2011) Tae Ho Lee et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Reduced Spine Density in Specific Regions of CA1 Pyramidal Neurons in Two Transgenic Mouse Models of Alzheimer's Disease

(2011) C. Perez-Cruz et al.   JOURNAL OF NEUROSCIENCE

Age-Related Changes in Mouse Taste Bud Morphology, Hormone Expression, and Taste Responsivity

(2011) Yu-Kyong Shin et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology

(2011) Ke Wu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Functional topography of the cerebellum for motor and cognitive tasks: An fMRI study

(2011) Catherine J. Stoodley et al.   NEUROIMAGE

Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity

(2011) Wayne Chadwick et al.   PLoS One

Eating and hypothalamus changes in behavioral-variant frontotemporal dementia

(2010) Olivier Piguet et al.   ANNALS OF NEUROLOGY

Increased Levels of Anxiety-related Behaviors in a Tsc2 Dominant Negative Transgenic Mouse Model of Tuberous Sclerosis

(2010) Dan Ehninger et al.   BEHAVIOR GENETICS

Signaling through BMPR-IA Regulates Quiescence and Long-Term Activity of Neural Stem Cells in the Adult Hippocampus

(2010) Helena Mira et al.   Cell Stem Cell

Vasoactive Intestinal Peptide-Null Mice Demonstrate Enhanced Sweet Taste Preference, Dysglycemia, and Reduced Taste Bud Leptin Receptor Expression

(2010) B. Martin et al.   DIABETES

Calcium-dependent mitochondrial function and dysfunction in neurons

(2010) Natalia B. Pivovarova et al.   FEBS Journal

C-type natriuretic peptide modulates bidirectional plasticity in hippocampal area CA1 in vitro

(2010) J.M. Decker et al.   NEUROSCIENCE

Ghrelin Is Produced in Taste Cells and Ghrelin Receptor Null Mice Show Reduced Taste Responsivity to Salty (NaCl) and Sour (Citric Acid) Tastants

(2010) Yu-Kyong Shin et al.   PLoS One

Minimal Peroxide Exposure of Neuronal Cells Induces Multifaceted Adaptive Responses

(2010) Wayne Chadwick et al.   PLoS One

Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice

(2010) Tobias Bittner et al.   PLoS One

Cerebellum and Nonmotor Function

(2009) Peter L. Strick et al.   Annual Review of Neuroscience

Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

(2009) Alexis M. Stranahan et al.   HIPPOCAMPUS

Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease

(2009) A. Auffret et al.   JOURNAL OF NEUROSCIENCE

Age-related memory impairments due to reduced blood glucose responses to epinephrine

(2009) Ken A. Morris et al.   NEUROBIOLOGY OF AGING

Neprilysin Deficiency-Dependent Impairment of Cognitive Functions in a Mouse Model of Amyloidosis

(2009) M. Hasan Mohajeri et al.   NEUROCHEMICAL RESEARCH

Synaptic AMPA Receptor Plasticity and Behavior

(2009) Helmut W. Kessels et al.   NEURON

Sweet Taste Receptor Expressed in Pancreatic β-Cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion

(2009) Yuko Nakagawa et al.   PLoS One

Hormones in the naso-oropharynx: endocrine modulation of taste and smell

(2009) Bronwen Martin et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Interaction of USF1/USF2 and α-Pal/Nrf1 to Fmr-1 promoter increases in mouse brain during aging

(2008) S. Prasad et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The calcium-sensing receptor in taste tissue

(2008) Ana San Gabriel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Growth hormone signaling and hippocampal neurogenesis: Insights from genetic models

(2008) Mark I. Ransome et al.   HIPPOCAMPUS

Modulation of taste sensitivity by GLP-1 signaling

(2008) Yu-Kyong Shin et al.   JOURNAL OF NEUROCHEMISTRY

Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia

(2008) S G Potkin et al.   MOLECULAR PSYCHIATRY

Control of mental activities by internal models in the cerebellum

(2008) Masao Ito   NATURE REVIEWS NEUROSCIENCE

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

(2008) Elizabeth K Davis et al.   Neural Development

Involvement of T1R3 in calcium-magnesium taste

(2008) Michael G. Tordoff et al.   PHYSIOLOGICAL GENOMICS

iTRAQ Analysis of Complex Proteome Alterations in 3xTgAD Alzheimer's Mice: Understanding the Interface between Physiology and Disease

(2008) Bronwen Martin et al.   PLoS One

Stereologic estimates of total spinophilin-immunoreactive spine number in area 9 and the CA1 field: Relationship with the progression of Alzheimer's disease

(2007) Afia Akram et al.   NEUROBIOLOGY OF AGING