Efficient farnesylation of an extended C-terminal C(x)3Xsequence motif expands the scope of the prenylated proteome

Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms

(2017) H Y Lau et al.   ONCOGENE

Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells

(2016) Charuta C. Palsuledesai et al.   ACS Chemical Biology

Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase

(2016) Benjamin C. Jennings et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Protein prenylation: unique fats make their mark on biology

(2016) Mei Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein lipid modifications-More than just a greasy ballast

(2016) Andreas Hentschel et al.   PROTEOMICS

Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue

(2016) Kiall F. Suazo et al.   Scientific Reports

A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes

(2016) Emily R Hildebrandt et al.   eLife

Simultaneous Site-Specific Dual Protein Labeling Using Protein Prenyltransferases

(2015) Yi Zhang et al.   BIOCONJUGATE CHEMISTRY

Pharmacological Inhibition of Protein Lipidation

(2015) Lakshmi Ganesan et al.   JOURNAL OF MEMBRANE BIOLOGY

Rapid Analysis of Protein Farnesyltransferase Substrate Specificity Using Peptide Libraries and Isoprenoid Diphosphate Analogues

(2014) Yen-Chih Wang et al.   ACS Chemical Biology

Quantitative Determination of Cellular Farnesyltransferase Activity: Towards Defining the Minimum Substrate Reactivity for Biologically Relevant Protein Farnesylation

(2014) Susan C. Flynn et al.   CHEMBIOCHEM

Targeted Reengineering of Protein Geranylgeranyltransferase Type I Selectivity Functionally Implicates Active-Site Residues in Protein-Substrate Recognition

(2013) Soumyashree A. Gangopadhyay et al.   BIOCHEMISTRY

Covalent lipid modifications of proteins

(2013) Marilyn D. Resh   CURRENT BIOLOGY

Restricted Substrate Specificity for the Geranylgeranyltransferase-I Enzyme in Cryptococcus neoformans: Implications for Virulence

(2013) Kyla Selvig et al.   EUKARYOTIC CELL

Simultaneous Dual Protein Labeling Using a Triorthogonal Reagent

(2013) Mohammad Rashidian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Farnesyl Diphosphate Analogues with Aryl Moieties Are Efficient Alternate Substrates for Protein Farnesyltransferase

(2012) Thangaiah Subramanian et al.   BIOCHEMISTRY

Recent advances in protein prenyltransferases: substrate identification, regulation, and disease interventions

(2012) Elaina A Zverina et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Expansion of Protein Farnesyltransferase Specificity Using “Tunable” Active Site Interactions

(2012) James L. Hougland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemoenzymatic Reversible Immobilization and Labeling of Proteins without Prior Purification

(2012) Mohammad Rashidian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Roles of Ras1 Membrane Localization during Candida albicans Hyphal Growth and Farnesol Response

(2011) Amy E. Piispanen et al.   EUKARYOTIC CELL

Structures ofCryptococcus neoformansProtein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens

(2011) Michael A. Hast et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anchoring of bacterial effectors to host membranes through host-mediated lipidation by prenylation: a common paradigm

(2011) Tasneem Al-Quadan et al.   TRENDS IN MICROBIOLOGY

Identification of a Novel Class of Farnesylation Targets by Structure-Based Modeling of Binding Specificity

(2011) Nir London et al.   PLoS Computational Biology

Post-translational myristoylation: Fat matters in cellular life and death

(2010) Dale D.O. Martin et al.   BIOCHIMIE

Evaluation of Alkyne-Modified Isoprenoids as Chemical Reporters of Protein Prenylation

(2010) Amanda J. DeGraw et al.   Chemical Biology & Drug Design

Selective labeling of polypeptides using protein farnesyltransferase via rapid oxime ligation

(2010) Mohammad Rashidian et al.   CHEMICAL COMMUNICATIONS

Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization ofLegionella pneumophilaEffector Proteins

(2010) Stanimir S. Ivanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Very Bright Green Fluorescent Proteins from the Pontellid Copepod Pontella mimocerami

(2010) Marguerite E. Hunt et al.   PLoS One

Context-Dependent Substrate Recognition by Protein Farnesyltransferase†

(2009) James L. Hougland et al.   BIOCHEMISTRY

Identification of Novel Peptide Substrates for Protein Farnesyltransferase Reveals Two Substrate Classes with Distinct Sequence Selectivities

(2009) James L. Hougland et al.   JOURNAL OF MOLECULAR BIOLOGY

Proteolytic processing of certain CaaX motifs can occur in the absence of the Rce1p and Ste24p CaaX proteases

(2009) Ranjith K. Krishnankutty et al.   YEAST

Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation

(2008) Zhong Guo et al.   EMBO JOURNAL

Rho Family GTPase Modification and Dependence on CAAXMotif-signaled Posttranslational Modification

(2008) Patrick J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries

(2008) A. E. Firth et al.   NUCLEIC ACIDS RESEARCH