ERK signalling as a regulator of cell motility

L-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway

(2016) Maiti J. Lommel et al.   FASEB JOURNAL

ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips

(2016) Susumu Tanimura et al.   JOURNAL OF CELL BIOLOGY

Regulating Rho GTPases and their regulators

(2016) Richard G. Hodge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oncogenic BRAF-Mediated Melanoma Cell Invasion

(2016) Hezhe Lu et al.   Cell Reports

MCRIP1, an ERK Substrate, Mediates ERK-Induced Gene Silencing during Epithelial-Mesenchymal Transition by Regulating the Co-Repressor CtBP

(2015) Kenji Ichikawa et al.   MOLECULAR CELL

Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2

(2015) Yue Zhou et al.   Nature Communications

Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex

(2014) Grzegorz Gawlak et al.   FASEB JOURNAL

Epidermal Growth Factor Activates the Rho GTPase-activating Protein (GAP) Deleted in Liver Cancer 1 via Focal Adhesion Kinase and Protein Phosphatase 2A

(2014) Archna Ravi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3

(2014) J. A. Galan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new mechanism of RhoA ubiquitination and degradation: Roles of SCF FBXL19 E3 ligase and Erk2

(2013) Jianxin Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphorylation of Rac1 T108 by Extracellular Signal-Regulated Kinase in Response to Epidermal Growth Factor: a Novel Mechanism To Regulate Rac1 Function

(2013) Junfeng Tong et al.   MOLECULAR AND CELLULAR BIOLOGY

ERK1/2 Regulate Exocytosis through Direct Phosphorylation of the Exocyst Component Exo70

(2012) Jinqi Ren et al.   DEVELOPMENTAL CELL

Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis

(2012) Jackie Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness

(2011) J. Hong et al.   CANCER RESEARCH

SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation

(2011) Susumu Tanimura et al.   GENES TO CELLS

ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex

(2011) Michelle C. Mendoza et al.   MOLECULAR CELL

An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis

(2011) R Lara et al.   ONCOGENE

EphA receptor signaling—Complexity and emerging themes

(2011) Hui Miao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia

(2010) M. Oser et al.   JOURNAL OF CELL SCIENCE

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

(2010) Sejeong Shin et al.   MOLECULAR CELL

Decoding signalling networks by mass spectrometry-based proteomics

(2010) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A nucleator arms race: cellular control of actin assembly

(2010) Kenneth G. Campellone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cortactin Phosphorylated by ERK1/2 Localizes to Sites of Dynamic Actin Regulation and Is Required for Carcinoma Lamellipodia Persistence

(2010) Laura C. Kelley et al.   PLoS One

Leveraging the membrane – cytoskeleton interface with myosin-1

(2010) Russell E. McConnell et al.   TRENDS IN CELL BIOLOGY

Filamins in cell signaling, transcription and organ development

(2010) Alex-Xianghua Zhou et al.   TRENDS IN CELL BIOLOGY

Extracellular Signal-Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression

(2009) H. Chen et al.   CANCER RESEARCH

The exocyst complex in polarized exocytosis

(2009) Bing He et al.   CURRENT OPINION IN CELL BIOLOGY

Differential VASP phosphorylation controls remodeling of the actin cytoskeleton

(2009) P. M. Benz et al.   JOURNAL OF CELL SCIENCE

PLC-γ1 and Rac1 Coregulate EGF-Induced Cytoskeleton Remodeling and Cell Migration

(2009) Siwei Li et al.   MOLECULAR ENDOCRINOLOGY

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport

(2009) Hidetaka Kosako et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility

(2009) M. D. Larrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA

(2008) Shuh-hei Fujishiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

(2008) David Michaelson et al.   JOURNAL OF CELL BIOLOGY

Filopodia: molecular architecture and cellular functions

(2008) Pieta K. Mattila et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The RSK family of kinases: emerging roles in cellular signalling

(2008) Rana Anjum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY