Neurons Derived from Induced Pluripotent Stem Cells of Patients with Down Syndrome Reproduce Early Stages of Alzheimer’s Disease Type Pathology in vitro

Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration

(2015) Aoife Murray et al.   STEM CELLS

N-butylidenephthalide Attenuates Alzheimer's Disease-Like Cytopathy in Down Syndrome Induced Pluripotent Stem Cell-Derived Neurons

(2015) Chia-Yu Chang et al.   Scientific Reports

Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease: Figure 1

(2015) Joel E. Beevers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Genetic Heterogeneity of Induced Pluripotent Stem Cells: Results from 24 Clones Derived from a Single C57BL/6 Mouse

(2015) Cheng Li et al.   PLoS One

RCAN1 Increases Aβ Generation by Promoting N-glycosylation via Oligosaccharyltransferase

(2014) Tan Wang et al.   Current Alzheimer Research

The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

(2014) Christina R. Muratore et al.   HUMAN MOLECULAR GENETICS

Aberrant Expression of RCAN1 in Alzheimer’s Pathogenesis: A New Molecular Mechanism and a Novel Drug Target

(2014) Yili Wu et al.   MOLECULAR NEUROBIOLOGY

Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors

(2014) Andrew A. Sproul et al.   PLoS One

Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors Is Displaced by Drug Candidates That Improve Cognitive Deficits

(2014) Nicholas J. Izzo et al.   PLoS One

Sox2, a key factor in the regulation of pluripotency and neural differentiation

(2014) Shuchen Zhang   World Journal of Stem Cells

Valproic acid enhances Oct4 promoter activity through PI3K/Akt/mTOR pathway activated nuclear receptors

(2013) Han Fang Teng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Modeling Huntington's disease with induced pluripotent stem cells

(2013) Julia A. Kaye et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Apoptosis in Down’s syndrome: lessons from studies of human and mouse models

(2012) Noemí Rueda et al.   APOPTOSIS

Alzheimer's disease and Down's syndrome: Treating two paths to dementia

(2012) Marc E. Weksler et al.   AUTOIMMUNITY REVIEWS

Background Mutations in Parental Cells Account for Most of the Genetic Heterogeneity of Induced Pluripotent Stem Cells

(2012) Margaret A. Young et al.   Cell Stem Cell

The Role of TMP21 in Trafficking and Amyloid-? Precursor Protein (APP) Processing in Alzheimer's Disease

(2012) Kelley Bromley-Brits et al.   Current Alzheimer Research

A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome

(2012) Y. Shi et al.   Science Translational Medicine

Modeling familial Alzheimer's disease with induced pluripotent stem cells

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease

(2011) Alvaro Rada-Iglesias et al.   Genome Medicine

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells

(2009) Chunliang Li et al.   HUMAN MOLECULAR GENETICS

Beta-Amyloid Deposition and the Aging Brain

(2009) Karen M. Rodrigue et al.   NEUROPSYCHOLOGY REVIEW