Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

(2013) Takayuki Kondo et al.   Cell Stem Cell

The MAPT H1 haplotype is associated with tangle-predominant dementia

(2012) Ismael Santa-Maria et al.   ACTA NEUROPATHOLOGICA

Effect of Complement CR1 on Brain Amyloid Burden During Aging and Its Modification by APOE Genotype

(2012) Madhav Thambisetty et al.   BIOLOGICAL PSYCHIATRY

Amyloid neurotoxicity is attenuated by metallothionein: dual mechanisms at work

(2012) Jong-Heon Kim et al.   JOURNAL OF NEUROCHEMISTRY

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

(2012) Eric M Reiman et al.   LANCET NEUROLOGY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood A  clearance in a mouse model of  -amyloidosis

(2012) J. M. Castellano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SMAD7 Directly Converts Human Embryonic Stem Cells to Telencephalic Fate by a Default Mechanism

(2012) Mohammad Zeeshan Ozair et al.   STEM CELLS

Neuroprotective effects of creatine

(2011) M. Flint Beal   AMINO ACIDS

Dissociation between the Processivity and Total Activity of γ-Secretase: Implications for the Mechanism of Alzheimer's Disease-Causing Presenilin Mutations

(2011) Omar Quintero-Monzon et al.   BIOCHEMISTRY

RETRACTED: Directed Conversion of Alzheimer's Disease Patient Skin Fibroblasts into Functional Neurons

(2011) Liang Qiang et al.   CELL

Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines

(2011) Christoph Bock et al.   CELL

γ-Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease: Disappointments and Hopes

(2011) Bruno P. Imbimbo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Modeling familial Alzheimer's disease with induced pluripotent stem cells

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial function

(2010) Sanghoon Kwon et al.   BMC BIOLOGY

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

Autosomal reciprocal translocations and 13/14 translocations: A population study

(2010) J. Nielsen et al.   CLINICAL GENETICS

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Presenilin transgenic mice as models of Alzheimer’s disease

(2009) Gregory A. Elder et al.   Brain Structure & Function

Cbl negatively regulates JNK activation and cell death

(2009) Andrew A Sproul et al.   CELL RESEARCH

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

Alcadein Cleavages by Amyloid β-Precursor Protein (APP) α- and γ-Secretases Generate Small Peptides, p3-Alcs, Indicating Alzheimer Disease-related γ-Secretase Dysfunction

(2009) Saori Hata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interruption of  -Catenin Signaling Reduces Neurogenesis in Alzheimer's Disease

(2009) P. He et al.   JOURNAL OF NEUROSCIENCE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

(2009) Tomoko Kuwabara et al.   NATURE NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Twenty-first century brain banking: practical prerequisites and lessons from the past: the experience of New York Brain Bank, Taub Institute, Columbia University

(2008) Jean Paul G. Vonsattel et al.   CELL AND TISSUE BANKING

Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology

(2008) Winnie S. Liang et al.   NEUROBIOLOGY OF AGING

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

(2008) Winnie S. Liang et al.   PHYSIOLOGICAL GENOMICS

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES