Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration

Mobile DNA elements in the generation of diversity and complexity in the brain

(2014) Jennifer A. Erwin et al.   NATURE REVIEWS NEUROSCIENCE

Adaptive Downregulation of Mitochondrial Function in Down Syndrome

(2013) Pablo Helguera et al.   Cell Metabolism

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

Usp16 contributes to somatic stem-cell defects in Down’s syndrome

(2013) Maddalena Adorno et al.   NATURE

Translating dosage compensation to trisomy 21

(2013) Jun Jiang et al.   NATURE

Deficits in human trisomy 21 iPSCs and neurons

(2013) J. P. Weick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells

(2012) Li B. Li et al.   Cell Stem Cell

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

(2012) Yichen Shi et al.   Nature Protocols

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

(2012) S. T. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

(2012) G. A. MacLean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome

(2012) Y. Shi et al.   Science Translational Medicine

Integration-Free Induced Pluripotent Stem Cells Model Genetic and Neural Developmental Features of Down Syndrome Etiology

(2012) James A. Briggs et al.   STEM CELLS

A Call for Standardized Naming and Reporting of Human ESC and iPSC Lines

(2011) Mai X. Luong et al.   Cell Stem Cell

Copy number variation and selection during reprogramming to pluripotency

(2011) Samer M. Hussein et al.   NATURE

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

(2011) H. Ban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome

(2010) S De Vita et al.   ONCOGENE

Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

(2009) Frédéric Delom et al.   Proteome Science

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

(2008) Claudia Canzonetta et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology

(2008) Anne M. Cataldo et al.   AMERICAN JOURNAL OF PATHOLOGY

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Quantitative Proteomics Characterization of a Mouse Embryonic Stem Cell Model of Down Syndrome

(2008) Yuqin Wang et al.   MOLECULAR & CELLULAR PROTEOMICS