Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics
出版年份 2017 全文链接
标题
Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics
作者
关键词
-
出版物
IUBMB LIFE
Volume 69, Issue 12, Pages 929-937
出版商
Wiley
发表日期
2017-12-01
DOI
10.1002/iub.1696
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- DNA damage responses and stress resistance: Concepts from bacterial SOS to metazoan immunity
- (2017) Ashley B. Williams et al. MECHANISMS OF AGEING AND DEVELOPMENT
- DNA repair targeted therapy: The past or future of cancer treatment?
- (2016) Navnath S. Gavande et al. PHARMACOLOGY & THERAPEUTICS
- Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
- (2016) Katherine Sullivan et al. PLoS One
- Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers
- (2015) Gurushankar Chandramouly et al. CHEMISTRY & BIOLOGY
- New insights into the mechanism of DNA mismatch repair
- (2015) Gloria X. Reyes et al. CHROMOSOMA
- Tumor neoantigens: building a framework for personalized cancer immunotherapy
- (2015) Matthew M. Gubin et al. JOURNAL OF CLINICAL INVESTIGATION
- Veliparib in combination with whole brain radiation therapy in patients with brain metastases: results of a phase 1 study
- (2015) Minesh P. Mehta et al. JOURNAL OF NEURO-ONCOLOGY
- Oxidatively induced DNA damage and its repair in cancer
- (2015) Miral Dizdaroglu MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Dicer Promotes Transcription Termination at Sites of Replication Stress to Maintain Genome Stability
- (2014) Stephane E. Castel et al. CELL
- Base excision repair: A critical player in many games
- (2014) Susan S. Wallace DNA REPAIR
- A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts
- (2014) Fei Huang et al. PLoS One
- A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation
- (2013) Ruth Plummer et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Break-induced replication: functions and molecular mechanism
- (2013) Anna Malkova et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- DNA-dependent Protein Kinase Regulates DNA End Resection in Concert with Mre11-Rad50-Nbs1 (MRN) and Ataxia Telangiectasia-mutated (ATM)
- (2013) Yi Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination
- (2013) S. Bhattacharjee et al. Open Biology
- An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression
- (2012) Mrinal Srivastava et al. CELL
- Mating-Type Genes and MAT Switching in Saccharomyces cerevisiae
- (2012) J. E. Haber GENETICS
- The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair
- (2012) Saikat Nandi et al. NUCLEIC ACIDS RESEARCH
- The Fission Yeast FANCM Ortholog Directs Non-Crossover Recombination During Meiosis
- (2012) A. Lorenz et al. SCIENCE
- Double-Strand Break End Resection and Repair Pathway Choice
- (2011) Lorraine S. Symington et al. Annual Review of Genetics
- Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines
- (2011) A Peasland et al. BRITISH JOURNAL OF CANCER
- DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells
- (2011) Zhiyong Mao et al. CELL CYCLE
- Regulation of endonuclease activity in human nucleotide excision repair
- (2011) Adebanke F. Fagbemi et al. DNA REPAIR
- The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
- (2011) Thomas Helleday Molecular Oncology
- How does DNA break during chromosomal translocations?
- (2011) M. Nambiar et al. NUCLEIC ACIDS RESEARCH
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Regulation of Homologous Recombination in Eukaryotes
- (2010) Wolf-Dietrich Heyer et al. Annual Review of Genetics
- Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2Checkpoint and Inhibition of Homologous Recombinational DNA Repair
- (2010) Meredith A. Morgan et al. CANCER RESEARCH
- Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses inBRCACarrier Ovarian Cancer Correlating With Platinum-Free Interval
- (2010) Peter C. Fong et al. JOURNAL OF CLINICAL ONCOLOGY
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate
- (2010) C. E. Strom et al. NUCLEIC ACIDS RESEARCH
- Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
- (2009) S. E. Golding et al. MOLECULAR CANCER THERAPEUTICS
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant
- (2009) Alexander Lorenz et al. NUCLEIC ACIDS RESEARCH
- Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
- (2009) M. L. Sos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transient Inhibition of ATM Kinase Is Sufficient to Enhance Cellular Sensitivity to Ionizing Radiation
- (2008) M. D. Rainey et al. CANCER RESEARCH
- RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination
- (2008) Louise J. Barber et al. CELL
- Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors
- (2008) R. Plummer et al. CLINICAL CANCER RESEARCH
- The Srs2 Helicase Activity Is Stimulated by Rad51 Filaments on dsDNA: Implications for Crossover Incidence during Mitotic Recombination
- (2008) Pauline Dupaigne et al. MOLECULAR CELL
- The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair
- (2008) Weili Sun et al. MOLECULAR CELL
- Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
- (2008) Eleni P. Mimitou et al. NATURE
- Identification of Holliday junction resolvases from humans and yeast
- (2008) Stephen C. Y. Ip et al. NATURE
- Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures
- (2008) Zhucheng Chen et al. NATURE
- A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
- (2008) Aude Dupré et al. Nature Chemical Biology
- Transcription-coupled DNA repair: two decades of progress and surprises
- (2008) Philip C. Hanawalt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication
- (2008) Akiko Hori et al. NUCLEIC ACIDS RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now