A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts
出版年份 2014 全文链接
标题
A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts
作者
关键词
-
出版物
PLoS One
Volume 9, Issue 6, Pages e100993
出版商
Public Library of Science (PLoS)
发表日期
2014-06-28
DOI
10.1371/journal.pone.0100993
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- DNA Repair by Homologous Recombination, But Not by Nonhomologous End Joining, Is Elevated in Breast Cancer Cells
- (2015) Zhiyong Mao et al. NEOPLASIA
- Rad51 replication fork recruitment is required for DNA damage tolerance
- (2013) Román González-Prieto et al. EMBO JOURNAL
- Targeting Aberrant DNA Double-Strand Break Repair in Triple-Negative Breast Cancer with Alpha-Particle Emitter Radiolabeled Anti-EGFR Antibody
- (2013) H. Song et al. MOLECULAR CANCER THERAPEUTICS
- ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks
- (2013) Sabrina Köcher et al. RADIOTHERAPY AND ONCOLOGY
- Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth
- (2012) M. A. Abengozar et al. BLOOD
- RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma
- (2012) Pierre Tennstedt et al. INTERNATIONAL JOURNAL OF CANCER
- An Optimized RAD51 Inhibitor That Disrupts Homologous Recombination without Requiring Michael Acceptor Reactivity
- (2012) Brian Budke et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibition of Homologous Recombination in Human Cells by Targeting RAD51 Recombinase
- (2012) Fei Huang et al. JOURNAL OF MEDICINAL CHEMISTRY
- The DNA damage response and cancer therapy
- (2012) Christopher J. Lord et al. NATURE
- RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells
- (2012) Brian Budke et al. NUCLEIC ACIDS RESEARCH
- Identification of Specific Inhibitors of Human RAD51 Recombinase Using High-Throughput Screening
- (2011) Fei Huang et al. ACS Chemical Biology
- Double-Strand Break End Resection and Repair Pathway Choice
- (2011) Lorraine S. Symington et al. Annual Review of Genetics
- The combination of chemotherapy with HVJ-E containing Rad51 siRNA elicited diverse anti-tumor effects and synergistically suppressed melanoma
- (2011) E Kiyohara et al. GENE THERAPY
- Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51
- (2011) Motoki Takaku et al. GENES TO CELLS
- Ku70 and Rad51 vary in their importance for the repair of doxorubicin- versus etoposide-induced DNA damage
- (2010) Ilona Schonn et al. APOPTOSIS
- Homologous recombination in cancer development, treatment and development of drug resistance
- (2010) T. Helleday CARCINOGENESIS
- Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
- (2010) Mary Ellen Moynahan et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA double-strand break repair activities in mammary epithelial cells--influence of endogenous p53 variants
- (2009) M. Keimling et al. CARCINOGENESIS
- Targeting the DNA damage response for cancer therapy
- (2009) Simon N. Powell et al. DNA REPAIR
- Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity
- (2009) A. Choudhury et al. MOLECULAR CANCER THERAPEUTICS
- DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange
- (2009) Takako Ishida et al. NUCLEIC ACIDS RESEARCH
- Mechanism of Eukaryotic Homologous Recombination
- (2008) Joseph San Filippo et al. Annual Review of Biochemistry
- The consequences of Rad51 overexpression for normal and tumor cells
- (2008) Hannah L. Klein DNA REPAIR
- Rad51 overexpression rescues radiation resistance in BRCA2-defective cancer cells
- (2008) Erika T. Brown et al. MOLECULAR CARCINOGENESIS
- Cytochrome P450 and Chemical Toxicology
- (2007) F. Peter Guengerich CHEMICAL RESEARCH IN TOXICOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started