PPARγ and RXR Ligands Disrupt the Inflammatory Cross-talk in the Hypoxic Breast Cancer Stem Cells Niche

The cross-talk between NF-κB and HIF-1: further evidence for a significant liaison: Figure 1

(2015) Agnes Görlach et al.   BIOCHEMICAL JOURNAL

Apolipoprotein Concentrations Are Elevated in Malignant Ovarian Cyst Fluids Suggesting That Lipoprotein Metabolism Is Dysregulated in Epithelial Ovarian Cancer

(2013) Iwona Podzielinski et al.   CANCER INVESTIGATION

Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling

(2013) Qishan Chen et al.   MEDIATORS OF INFLAMMATION

Expression and clinical significance of apolipoprotein E in pancreatic ductal adenocarcinoma

(2013) Jiong Chen et al.   MEDICAL ONCOLOGY

Peroxisome Proliferator Activated Receptor-α/Hypoxia Inducible Factor-1α Interplay Sustains Carbonic Anhydrase IX and Apoliprotein E Expression in Breast Cancer Stem Cells

(2013) Alessio Papi et al.   PLoS One

Nuclear Control of the Inflammatory Response in Mammals by Peroxisome Proliferator-Activated Receptors

(2013) Stéphane Mandard et al.   PPAR Research

The Role of Peroxisome Proliferator-Activated Receptor-γ in Breast Cancer

(2012) Ioly Kotta-Loizou et al.   Anti-Cancer Agents in Medicinal Chemistry

Contrasting Hypoxic Effects on Breast Cancer Stem Cell Hierarchy Is Dependent on ER-  Status

(2012) H. Harrison et al.   CANCER RESEARCH

New strategies for targeting the hypoxic tumour microenvironment in breast cancer

(2012) Carol Ward et al.   CANCER TREATMENT REVIEWS

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells

(2012) A Papi et al.   CELL DEATH AND DIFFERENTIATION

Molecular Mechanisms Regulating Matrix Metalloproteinases

(2012) Christina Piperi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Slug Controls Stem/Progenitor Cell Growth Dynamics during Mammary Gland Morphogenesis

(2012) Mayssa Nassour et al.   PLoS One

Inflamm-aging of the stem cell niche: Breast cancer as a paradigmatic example

(2011) Massimiliano Bonafè et al.   BIOESSAYS

Peroxisome proliferator-activated receptors and cancer: challenges and opportunities

(2011) Jihan Youssef et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

(2011) Y. Lou et al.   CANCER RESEARCH

Roles of Metalloproteases in Metastatic Niche

(2011) N. Rucci et al.   CURRENT MOLECULAR MEDICINE

Exosome signaling in mammary gland development and cancer

(2011) An Hendrix et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

(2011) Hasan Korkaya et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6

(2011) Ken Saito et al.   NUCLEIC ACIDS RESEARCH

Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells

(2011) Jenny A. Rudnick et al.   PLoS One

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

RXRγ and PPARγ ligands in combination to inhibit proliferation and invasiveness in colon cancer cells

(2010) Alessio Papi et al.   CANCER LETTERS

Retinoid signaling regulates breast cancer stem cell differentiation

(2010) Christophe Ginestier et al.   CELL CYCLE

Intracellular and Extracellular MicroRNAs in Breast Cancer

(2010) C. Corcoran et al.   CLINICAL CHEMISTRY

TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype

(2010) Gianluca Storci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting Breast Cancer Stem Cells

(2010) Suling Liu et al.   JOURNAL OF CLINICAL ONCOLOGY

Hypoxia-Induced Mitogenic Factor (HIMF/FIZZ1/RELM ) Increases Lung Inflammation and Activates Pulmonary Microvascular Endothelial Cells via an IL-4-Dependent Mechanism

(2010) K. Yamaji-Kegan et al.   JOURNAL OF IMMUNOLOGY

miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor   Expression

(2010) E. K. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

Combined Low Doses of PPARγ and RXR Ligands Trigger an Intrinsic Apoptotic Pathway in Human Breast Cancer Cells

(2009) Daniela Bonofiglio et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNAs: Novel regulators in the hallmarks of human cancer

(2009) Kai Ruan et al.   CANCER LETTERS

Therapeutic Potential of "Rexinoids" in Cancer Prevention and Treatment

(2009) T. Tanaka et al.   CANCER RESEARCH

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARγ and RXRγ ligands act synergistically as potent antineoplastic agentsin vitroandin vivoglioma models

(2009) Alessio Papi et al.   JOURNAL OF NEUROCHEMISTRY

Fibroblasts Isolated from Common Sites of Breast Cancer Metastasis Enhance Cancer Cell Growth Rates and Invasiveness in an Interleukin-6–Dependent Manner

(2008) Adam W. Studebaker et al.   CANCER RESEARCH

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION

Fibroblast migration is mediated by CD44-dependent TGF  activation

(2008) P. S. Acharya et al.   JOURNAL OF CELL SCIENCE

Cyclooxygenase-2/carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells

(2008) Pasquale Sansone et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes

(2008) Javier Conde-Vancells et al.   JOURNAL OF PROTEOME RESEARCH

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE