Granzyme K-deficient mice show no evidence of impaired antiviral immunity

Orphan granzymes find a home

(2015) Niels Bovenschen et al.   IMMUNOLOGICAL REVIEWS

Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state

(2015) Felipe Andrade   IMMUNOLOGICAL REVIEWS

Analysis of the evolution of granule associated serine proteases of immune defence (GASPIDs) suggests a revised nomenclature

(2014) Jamshaid Ahmad et al.   BIOLOGICAL CHEMISTRY

Granzyme B Promotes Cytotoxic Lymphocyte Transmigration via Basement Membrane Remodeling

(2014) Monica D. Prakash et al.   IMMUNITY

The Perforin Pore Facilitates the Delivery of Cationic Cargos

(2014) Sarah E. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Holistic View on the Extended Substrate Specificities of Orthologous Granzymes

(2014) Kim Plasman et al.   JOURNAL OF PROTEOME RESEARCH

Substrate Specificities of the Granzyme Tryptases A and K

(2014) Kim Plasman et al.   JOURNAL OF PROTEOME RESEARCH

Granzyme K synergistically potentiates LPS-induced cytokine responses in human monocytes

(2014) A. C. Wensink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blessing or curse? Proteomics in granzyme research

(2014) Lars T. Joeckel et al.   Proteomics Clinical Applications

Are all granzymes cytotoxic in vivo?

(2013) Lars T. Joeckel et al.   BIOLOGICAL CHEMISTRY

Interleukin-1R Signaling Is Essential for Induction of Proapoptotic CD8 T Cells, Viral Clearance, and Pathology during Lymphocytic Choriomeningitis Virus Infection in Mice

(2012) Lars T. Joeckel et al.   JOURNAL OF VIROLOGY

Granzyme B in injury, inflammation, and repair

(2012) Paul R. Hiebert et al.   TRENDS IN MOLECULAR MEDICINE

Mouse granzyme K has pro-inflammatory potential

(2011) L T Joeckel et al.   CELL DEATH AND DIFFERENTIATION

Granzyme K Activates Protease-Activated Receptor-1

(2011) Dawn M. Cooper et al.   PLoS One

Valosin-Containing Protein Cleavage by Granzyme K Accelerates an Endoplasmic Reticulum Stress Leading to Caspase-Independent Cytotoxicity of Target Tumor Cells

(2010) Y. Guo et al.   JOURNAL OF IMMUNOLOGY

A Role for Granzyme M in TLR4-Driven Inflammation and Endotoxicosis

(2010) D. A. Anthony et al.   JOURNAL OF IMMUNOLOGY

Ignition of p53 Bomb Sensitizes Tumor Cells to Granzyme K-Mediated Cytolysis

(2009) G. Hua et al.   JOURNAL OF IMMUNOLOGY

Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response

(2008) Sunil S. Metkar et al.   IMMUNITY

Granzyme K Displays Highly Restricted Substrate Specificity That Only Partially Overlaps with Granzyme A

(2008) Niels Bovenschen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity

(2008) Yuming Guo et al.   MOLECULAR IMMUNOLOGY

Non-apoptotic functions of granzymes

(2008) V. Romero et al.   TISSUE ANTIGENS