Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans
出版年份 2017 全文链接
标题
Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 26, Issue 15, Pages 2864-2873
出版商
Oxford University Press (OUP)
发表日期
2017-04-27
DOI
10.1093/hmg/ddx167
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS
- (2015) Benedetta Parodi et al. ACTA NEUROPATHOLOGICA
- Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight
- (2015) Aashiq Hussain Bhat et al. BIOMEDICINE & PHARMACOTHERAPY
- The emerging role of Nrf2 in mitochondrial function
- (2015) Albena T. Dinkova-Kostova et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro
- (2015) Melanie S. Brennan et al. PLoS One
- Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate’s protective effect in EAE
- (2014) Hui Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Nrf2 augments skeletal muscle regeneration after ischaemia-reperfusion injury
- (2014) Othman Al-Sawaf et al. JOURNAL OF PATHOLOGY
- High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects
- (2014) Sunil Sahdeo et al. MITOCHONDRION
- Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats
- (2014) Aline Couturier et al. BMC Pharmacology & Toxicology
- Role of Nrf2 in Oxidative Stress and Toxicity
- (2013) Qiang Ma Annual Review of Pharmacology and Toxicology
- Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain
- (2013) Inmaculada García-Ruiz et al. BMC BIOLOGY
- Efficient mitochondrial biogenesis drives incomplete penetrance in Leber’s hereditary optic neuropathy
- (2013) Carla Giordano et al. BRAIN
- Clinical features of MS associated with Leber hereditary optic neuropathy mtDNA mutations
- (2013) G. Pfeffer et al. NEUROLOGY
- Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice
- (2013) Yu-Kun Jennifer Zhang et al. PLoS One
- Mitochondrial Dysfunction in Neuromuscular Disorders
- (2013) Christos D. Katsetos et al. Seminars in Pediatric Neurology
- Defects in mitochondrial localization and ATP synthesis in the mdx mouse model of Duchenne muscular dystrophy are not alleviated by PDE5 inhibition
- (2012) J. M. Percival et al. HUMAN MOLECULAR GENETICS
- Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters
- (2012) De-Hyung Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis
- (2012) Robert J. Fox et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
- (2011) Ralf A. Linker et al. BRAIN
- Mitochondrial dysfunction in ALS
- (2011) Mauro Cozzolino et al. PROGRESS IN NEUROBIOLOGY
- Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes
- (2010) Xiaoyu Li et al. BIOCHEMICAL PHARMACOLOGY
- Is multiple sclerosis a mitochondrial disease?
- (2009) Peizhong Mao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease
- (2008) Marcus J. Calkins et al. ANTIOXIDANTS & REDOX SIGNALING
- The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist
- (2008) Hua Tang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype
- (2008) Tina Wenz et al. Cell Metabolism
- Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
- (2008) Claude A. Piantadosi et al. CIRCULATION RESEARCH
- Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
- (2008) C.J. Harvey et al. FREE RADICAL BIOLOGY AND MEDICINE
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity
- (2008) T. Yamamoto et al. MOLECULAR AND CELLULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now